6233-83-6
中文名稱
醋酸縮宮素
英文名稱
Oxytocin, monoacetate (salt)
CAS
6233-83-6
分子式
C2H4O2
分子量
60.052
MOL 文件
6233-83-6.mol
更新日期
2024/12/15 15:04:05
6233-83-6 結(jié)構(gòu)式
基本信息
中文別名
醋酸縮宮素羥可待酮鑒別
羥可待酮鑒別 USP標(biāo)準(zhǔn)品
英文別名
Pitocin AcetateSynpitan Acetate
Uteracon Acetate
Orasthin Acetate
Perlacton Acetate
Syntocinon Acetate
50-56-6 (free base)
Oxytocin Monoacetate
α-Hypophamine acetate
Oxytocin Identification
所屬類別
分析化學(xué)：藥典標(biāo)準(zhǔn)品和雜質(zhì)標(biāo)準(zhǔn)品物理化學(xué)性質(zhì)
儲存條件-20°C儲存
溶解度DMSO:44.0(Max Conc. mg/mL);41.23(Max Conc. mM)
Water:50.0(Max Conc. mg/mL);46.85(Max Conc. mM)
Water:50.0(Max Conc. mg/mL);46.85(Max Conc. mM)
形態(tài)結(jié)晶固體
顏色White to off-white
InChIKeyDSZOEVVLZMNAEH-SIVBSZNNNA-N
常見問題列表
生物活性
Oxytocin acetate 是一種多效的下丘腦肽 (hypothalamic peptide)，有助于分娩、哺乳和親社會行為。Oxytocin acetate 可以作為一種壓力應(yīng)對分子，具有抗炎、抗氧化劑和保護(hù)作用，特別是在面對逆境或創(chuàng)傷時。體內(nèi)研究
During the LMA task, rat core body temperature are modestly decreased.?Oxytocin acetate (subcutaneous?injection; 0.1?mg/kg-0.3 mg/kg; single dose) produces significantly greater hypothermia (at 0.3 mg/kg) than either saline or the two lower doses of oxytocin. Oxytocin at 0.3?mg/kg produces a significantly greater decrease in temperature than vehicle between 15-60?min post injection, whereas 0.1?mg/kg slightly decreases temperature at the 30?min time point only.Oxytocin acetate (0.1?mg/kg) engages in significantly more body sniffing and ano-genital sniffing compared with saline controls. It also increases the total time spent in social interaction (71.6±4.3?s), compared to those receiving vehicle (56.9±4.1?s).
| Animal Model: | Fifty-six male Lister-hooded rats (150–200?g) |
| Dosage: | 0.1?mg/kg-0.3 mg/kg |
| Administration: | Subcutaneous?injection; 0.1?mg/kg-0.3 mg/kg; single dose |
| Result: | Produced significantly greater hypothermia (at 0.3 mg/kg) than the saline group. |