Identification | Back Directory | [Name]
Oxytocin, monoacetate (salt) | [CAS]
6233-83-6 | [Synonyms]
Pitocin Acetate Synpitan Acetate Uteracon Acetate Orasthin Acetate Perlacton Acetate Syntocinon Acetate 50-56-6 (free base) Oxytocin Monoacetate α-Hypophamine acetate Oxytocin Identification Oxytocic hormone acetate Oxytocin, monoacetate (salt) Oxytocin acetate (50-56-6 free base) Oxytocin Identification (15 mg) (COLD SHIPMENT REQUIRED) Α-HYPOPHAMINE ACETATE;OXYTOCIC HORMONE ACETATE;50-56-6 (FREE BASE) | [EINECS(EC#)]
228-347-5 | [Molecular Formula]
C2H4O2 | [MOL File]
6233-83-6.mol | [Molecular Weight]
60.052 |
Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:44.0(Max Conc. mg/mL);41.23(Max Conc. mM) Water:50.0(Max Conc. mg/mL);46.85(Max Conc. mM) | [form ]
A crystalline solid | [color ]
White to off-white | [InChIKey]
DSZOEVVLZMNAEH-SIVBSZNNNA-N |
Hazard Information | Back Directory | [Description]
Oxytocin acetate is an analog of oxytocin, a hormone that stimulates the uterus during labor. It is synthesized by chemically conjugation oxytocin with acetic acid. The stability of this molecule has been proven to be higher than that of oxytocin. This drug demonstrates a stronger binding affinity for the oxytocin receptor, which may be attributed to its increased molecular weight. Additionally, oxytocin acetate has been observed to increase levels of growth factors and fatty acids in tissues when administered intramuscularly, while also stimulating neurotransmission. It exhibits a shorter onset latency and a longer duration of action compared to other analogs. Apart from its medical applications, oxytocin acetate can also serve as a disinfectant in cosmetic use and as an amide-forming agent in organic synthesis reactions.
| [Chemical Properties]
White Solid | [Uses]
The principal uterus-contracting and lactation-stimulating hormone of the posterior pituitary gland. | [Mechanism of action]
The actions of oxytocin are mediated by a single G protein-coupled receptor distributed in many peripheral tissues and specific brain areas. Oxytocin secreted into the circulation stimulates uterine contractions during labor and stimulates milk ejection during lactation.
| [References]
[1] MOSTAFA GHASEMISARABBADIEH; Benjamín R S; Sveinbj?rn Gizurarson. The effect of trehalose, antioxidants, and acetate buffer concentration on oxytocin stability[J]. Journal of Peptide Science, 2021. DOI:10.1002/psc.3324. |
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