Torin 1
- $28 - $4500
- Product name: Torin 1
- CAS: 1222998-36-8
- MF: C35H28F3N5O2
- MW: 607.62
- EINECS:
- MDL Number:MFCD18782653
- Synonyms:1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h]-1,6-naphthyridin-2(1H)-one;1-[4-(4-PROPANOYLPIPERAZIN-1-YL)-3-(TRIFLUOROMETHYL)PHENYL]-9-QUINOLIN-3-YLBENZO[H][1,6]NAPHTHYRIDIN-2-ONE;Torin 1;Benzo[h]-1,6-naphthyridin-2(1H)-one, 1-[4-[4-(1-oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-;1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h]-1,6-naphthyridin-2(1H)-one Torin 1;Torin 1 1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h]-1,6-naphthyridin-2(1H)-one;1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one;Torin 1, >=98%
35 prices
Selected condition:
Brand
- AK Scientific
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 1unit
- 5mg
- 10mg
- 25mg
- 50
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- ManufacturerAK Scientific
- Product numberY0294
- Product descriptionTorin1
- Packaging50mg
- Price$640
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0294
- Product descriptionTorin1
- Packaging10mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8312
- Product descriptionTorin1
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8312
- Product descriptionTorin1
- Packaging5mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8312
- Product descriptionTorin1
- Packaging25mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60098
- Product descriptionTorin1 ≥98%
- Packaging10mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1833
- Product descriptionTorin1 98%
- Packaging5mg
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546140
- Product descriptionTorin 1 >98%
- Packaging5mg
- Price$190.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546140
- Product descriptionTorin 1 >98%
- Packaging25mg
- Price$521.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146133
- Product descriptionTorin1 >98%
- Packaging100mg
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146133
- Product descriptionTorin1 >98%
- Packaging250mg
- Price$1356.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146133
- Product descriptionTorin1 >98%
- Packaging1g
- Price$2691.1
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFT103463
- Product descriptionTorin 1
- Packaging10mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFT103463
- Product descriptionTorin 1
- Packaging50mg
- Price$437.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10997
- Product descriptionTorin 1 ≥95%
- Packaging10mg
- Price$146
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10997
- Product descriptionTorin 1 ≥95%
- Packaging25mg
- Price$330
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | Y0294 | Torin1 | 50mg | $640 | 2021-12-16 | Buy |
AK Scientific | Y0294 | Torin1 | 10mg | $218 | 2021-12-16 | Buy |
ApexBio Technology | A8312 | Torin1 | 1unit | $28 | 2021-12-16 | Buy |
ApexBio Technology | A8312 | Torin1 | 5mg | $70 | 2021-12-16 | Buy |
ApexBio Technology | A8312 | Torin1 | 25mg | $270 | 2021-12-16 | Buy |
Arctom | CFN60098 | Torin1 ≥98% | 10mg | $218 | 2021-12-16 | Buy |
Axon Medchem | Axon1833 | Torin1 98% | 5mg | $99 | 2021-12-16 | Buy |
Biorbyt Ltd | orb546140 | Torin 1 >98% | 5mg | $190.4 | 2021-12-16 | Buy |
Biorbyt Ltd | orb546140 | Torin 1 >98% | 25mg | $521.9 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146133 | Torin1 >98% | 100mg | $765 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146133 | Torin1 >98% | 250mg | $1356.6 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146133 | Torin1 >98% | 1g | $2691.1 | 2021-12-16 | Buy |
Biosynth Carbosynth | FT103463 | Torin 1 | 10mg | $125 | 2021-12-16 | Buy |
Biosynth Carbosynth | FT103463 | Torin 1 | 50mg | $437.5 | 2021-12-16 | Buy |
Cayman Chemical | 10997 | Torin 1 ≥95% | 10mg | $146 | 2024-03-01 | Buy |
Cayman Chemical | 10997 | Torin 1 ≥95% | 25mg | $330 | 2024-03-01 | Buy |
Properties
Melting point :>223°C (dec.)
Boiling point :817.2±65.0 °C(Predicted)
Density :1.362
storage temp. :+2C to +8C
solubility :Soluble in DMSO (up to 8 mg/ml).
form :Yellowish-white powder
pka :4.19±0.20(Predicted)
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Boiling point :817.2±65.0 °C(Predicted)
Density :1.362
storage temp. :+2C to +8C
solubility :Soluble in DMSO (up to 8 mg/ml).
form :Yellowish-white powder
pka :4.19±0.20(Predicted)
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Safety Information
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Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Torin 1 is a potent and selective inhibitor of mTOR (IC50 = 2 and 10 nM for mTORC1 and mTORC2, respectively). It shows over 100-fold selectivity for mTOR over PI3Kα and other PI3K-like kinases, including ATM, DNA-PK, and hVps34, as well as 450 other protein kinases. Torin 1, is efficacious at a dose of 20 mg/kg in inhibiting downstream effectors of mTOR in mice.Related product price
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