Acalabrutinib
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- $32 - $1744
- Product name: Acalabrutinib
- CAS: 1420477-60-6
- MF: C26H23N7O2
- MW: 465.51
- EINECS:814-272-0
- MDL Number:MFCD29472294
- Synonyms:acalabrutinib;Benzamide, 4-[8-amino-3-[(2S)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl-;ACP196,Acalabrutinib;4-[8-Amino-3-[(2S)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinylbenzamide;(S)-4-(8-amino-3-(1-but-2-ynoylpyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide;Acalabrutinib (ACP-196);EOS-60753;ACP-196; ACP196; ACP 196
32 prices
Selected condition：
Brand
- Abosyn
- Activate Scientific
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
- Usbiological
Package
- 1mg
- 2mg
- 2.5mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1g
- 5G
- ManufacturerAbosyn
- Product number10-3526
- Product description(S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide 95%-98%
- Packaging2mg
- Price$870
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS59887
- Product descriptionAcalabrutinib 95% ee
- Packaging5G
- Price$1744
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS59887
- Product descriptionAcalabrutinib 95% ee
- Packaging1g
- Price$655
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS59887
- Product descriptionAcalabrutinib 95% ee
- Packaging250mg
- Price$314
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS59887
- Product descriptionAcalabrutinib 95% ee
- Packaging100mg
- Price$154
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS59887
- Product descriptionAcalabrutinib 95% ee
- Packaging25mg
- Price$94
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX3870
- Product descriptionAcalabrutinib
- Packaging1mg
- Price$46
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX3870
- Product descriptionAcalabrutinib
- Packaging5mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX3870
- Product descriptionAcalabrutinib
- Packaging10mg
- Price$94
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0027385
- Product description(S)-4-(8-AMINO-3-(1-(BUT-2-YNOYL)PYRROLIDIN-2-YL)IMIDAZO[1,5-A]PYRAZIN-1-YL)-N-(PYRIDIN-2-YL)BENZAMIDE 95.00%
- Packaging5MG
- Price$497.56
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6185
- Product descriptionACP-196
- Packaging5mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6185
- Product descriptionACP-196
- Packaging25mg
- Price$278
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6185
- Product descriptionACP-196
- Packaging100mg
- Price$698
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA138815
- Product descriptionAcalabrutinib
- Packaging10mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA138815
- Product descriptionAcalabrutinib
- Packaging25mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA138815
- Product descriptionAcalabrutinib
- Packaging50mg
- Price$200
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Abosyn | 10-3526 | (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide 95%-98% | 2mg | $870 | 2021-12-16 | Buy |
| Activate Scientific | AS59887 | Acalabrutinib 95% ee | 5G | $1744 | 2021-12-16 | Buy |
| Activate Scientific | AS59887 | Acalabrutinib 95% ee | 1g | $655 | 2021-12-16 | Buy |
| Activate Scientific | AS59887 | Acalabrutinib 95% ee | 250mg | $314 | 2021-12-16 | Buy |
| Activate Scientific | AS59887 | Acalabrutinib 95% ee | 100mg | $154 | 2021-12-16 | Buy |
| Activate Scientific | AS59887 | Acalabrutinib 95% ee | 25mg | $94 | 2021-12-16 | Buy |
| AK Scientific | X3870 | Acalabrutinib | 1mg | $46 | 2021-12-16 | Buy |
| AK Scientific | X3870 | Acalabrutinib | 5mg | $75 | 2021-12-16 | Buy |
| AK Scientific | X3870 | Acalabrutinib | 10mg | $94 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0027385 | (S)-4-(8-AMINO-3-(1-(BUT-2-YNOYL)PYRROLIDIN-2-YL)IMIDAZO[1,5-A]PYRAZIN-1-YL)-N-(PYRIDIN-2-YL)BENZAMIDE 95.00% | 5MG | $497.56 | 2021-12-16 | Buy |
| ApexBio Technology | B6185 | ACP-196 | 5mg | $75 | 2021-12-16 | Buy |
| ApexBio Technology | B6185 | ACP-196 | 25mg | $278 | 2021-12-16 | Buy |
| ApexBio Technology | B6185 | ACP-196 | 100mg | $698 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA138815 | Acalabrutinib | 10mg | $80 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA138815 | Acalabrutinib | 25mg | $150 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA138815 | Acalabrutinib | 50mg | $200 | 2021-12-16 | Buy |
Properties
Melting point :>133°C (dec.)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Soluble in DMSO (up to at least 25 mg/ml)
pka :11.47±0.70(Predicted)
form :solid
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :WDENQIQQYWYTPO-IBGZPJMESA-N
SMILES :C(NC1=NC=CC=C1)(=O)C1=CC=C(C2=C3N(C([C@@H]4CCCN4C(=O)C#CC)=N2)C=CN=C3N)C=C1
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Soluble in DMSO (up to at least 25 mg/ml)
pka :11.47±0.70(Predicted)
form :solid
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :WDENQIQQYWYTPO-IBGZPJMESA-N
SMILES :C(NC1=NC=CC=C1)(=O)C1=CC=C(C2=C3N(C([C@@H]4CCCN4C(=O)C#CC)=N2)C=CN=C3N)C=C1
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Acalabrutinib (ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor with an IC50 of 3 nM, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity over ibrutinib with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, respectively) and no activity against EGFR.More related product prices
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Suppliers and manufacturers
Capot Chemical Co.,Ltd.
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
