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Lisinopril Dihydrate

Lisinopril Dihydrate Struktur
83915-83-7
CAS-Nr.
83915-83-7
Englisch Name:
Lisinopril Dihydrate
Synonyma:
Lisinopril;Zestfil;renacor;isinopriL;Lisinopril API;(S) Lisinopril;L-154826:MK-521;LISINOPRIL HYDRATE;Lisinopril99%Assay;MK-521 (dihydrate)
CBNumber:
CB3113756
Summenformel:
C21H33N3O6
Molgewicht:
423.51
MOL-Datei:
83915-83-7.mol

Lisinopril Dihydrate Eigenschaften

Schmelzpunkt:
148 °C
alpha 
25405 -120° (c = 1 in 0.25M pH 6.4 zinc acetate); 25436 -96° (c = 1 in 0.25M pH 6.4 zinc acetate)
Brechungsindex
-45 ° (C=1, 0.25mol/L Zinc Acetate Buffer)
storage temp. 
2-8°C
L?slichkeit
H2O: ≥10 mg/mL
pka
2.5, 4.0, 6.7, 10.1(at 25℃)
Aggregatzustand
solid
Farbe
white
Wasserl?slichkeit
H2O: ≥10mg/mL
DMSO: ~6.5mg/mL (with heating and sonicating)
Merck 
14,5516
Stabilit?t:
Hygroscopic
CAS Datenbank
83915-83-7(CAS DataBase Reference)
EPA chemische Informationen
L-Proline, N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-, hydrate (1:2) (83915-83-7)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi,Xn
R-S?tze: 20/21/22
S-S?tze: 22-24/25-36
WGK Germany  3
RTECS-Nr. TW3589990
HazardClass  IRRITANT
HS Code  2933995300
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H373 Kann die Organe sch?digen bei l?ngerer oder wiederholter Exposition. Spezifische Zielorgan-Toxizit?t (wiederholte Exposition) Kategorie 2 Warnung P260, P314, P501
Sicherheit
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P260 Dampf/Aerosol/Nebel nicht einatmen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P308+P313 BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P405 Unter Verschluss aufbewahren.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Lisinopril Dihydrate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Beschreibung

Lisinopril is an angiotensin converting enzyme inhibitor structurally related to enalaprilat. It is reportedly useful in the management of hypertension and congestive heart failure.

Chemische Eigenschaften

White to Off-White Crystalline Powder

Allgemeine Beschreibung

Lisinopril, 1-[N2-[S-1-carboxy-3-phenylpropyl]-L-lysyl]-L-proline dihydrate (Prinivil, Zestril), is alysine derivative of enalaprilat, the active metabolite ofenalapril. Like all ACE inhibitors, it is an active site-directedinhibitor of the enzyme, with the zinc ion used in an effectivebinding interaction at a stoichiometric ratio of 1:1. The pharmacologicaleffects of lisinopril are similar to those of captopriland enalapril.

Clinical Use

Many new ACE inhibitors became available for the treatmentof hypertension following the clinical effectivenessof enalapril. Enalapril is a non–thiol-containing ACE inhibitordevoid of the side effects of rash and loss of thesense of taste characteristic of the thiol-containing compoundcaptopril. With the exception of the phosphoruscontainingfosinopril, these antihypertensive agents havea 2-, like the prototypical drug captopril,are used in the treatment of mild-to-moderate hypertension,either alone or in conjunction with diuretics orcalcium channel blockers.

Lisinopril Dihydrate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Lisinopril Dihydrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 386)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hangzhou ICH Biofarm Co., Ltd
+86-0571-28186870; +undefined8613073685410
sales@ichemie.com China 1010 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 20267 58
Hangzhou Hyper Chemicals Limited
+86-0086-57187702781 +8613675893055
info@hyper-chem.com China 295 58
hebei hongtan Biotechnology Co., Ltd
+86-86-1913198-3935 +8617331935328
sales03@chemcn.cn China 970 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649
sarah@tnjone.com China 1143 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497
sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3009 60
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
bruce@xrdchem.cn CHINA 566 55
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29879 58

83915-83-7()Verwandte Suche:


  • Lisinopril Related Compound A (15 mg) ((S)-2-{(3S,8aS)-3-(4-aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl}-4-phenylbutanoic acid)
  • (S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate
  • LIQUID PRED (prednisone),Lisinopril
  • Lisinopril API
  • Lisinopril (Zestril)
  • Lisinopril for system suitability A
  • Lisinopril for peak identification
  • N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline,hydrate (1:2)
  • Lisinopril for system suitability
  • LISINOPRIL-D5 HYDRATE
  • LISINOPRIL HYDRATE
  • (ds)-1-[n2-(1-carboxy-3-phenylpropyl)-l-prolinedihydrate
  • (s)-1-(n(sup2)-(1-carboxy-3-phenylpropyl)-l-lysyl)-l-prolinedihydrate
  • (S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate, MK-521
  • L-154826:MK-521
  • Zestfil
  • (S) -1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]-L-praline dihydrate
  • (2S)-1-[(2S)-6-Amino-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid dihydrate
  • (S)-(-)-1-[N-(1-Carboxy-3-phenylpropyl)-L-lysinyl]-L-proline dihydrate
  • Lisinopril,(S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate, MK-521
  • Lisinopril (300 mg)
  • 1-(n(sup2)-(1-carboxy-3-phenylpropyl)-l-lysyl)-,dihydrate,(s)-l-prolin
  • renacor
  • N-[2-[4-[[[(Cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]5-methylpyrazinecarboxamide dihydrate
  • Lisinopril dihydrate USP24,25 EP2000(III)
  • (S) Lisinopril
  • (S)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]L-proline, Dihydrate, MK-521, Acerbon, Alapril, Carace, Coric, Novatec, Prinil, Prinivil, Tensopril, Vivatec, Zestril
  • (2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenyl-propyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
  • Lisinopril99%Assay
  • LisinoprilC21H31H305*2H20
  • 1-[Nalpha-[(S)-1-Carboxy-3-phenylpropyl]-L-lysyl]-L-proline
  • (S)-1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate
  • LISINOPRIL DEHYDRATE
  • (S)-1-{(S)-6-Amino-2-[((S)-1-carboxy-3-phenyl)propylamino]hexanoyl}pyrrolidine-2-carboxylic acid dihydrate
  • LISINOPRIL DIHYDRATE
  • (2S)-1-[(2S)-6-Amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino] hexanoyl] pyrrole-2-carboxylic acid dihydrate
  • Lisinopril 83915-83-7
  • LISINOPRI (DIHYDRATE) (LMK-521 (DIHYDRATE))
  • (S)-Lisinopril Dihydrate
  • LisinoprilDihydrate>
  • Lisinopril for peak identification CRS
  • Lisinopril dihydrate CRS
  • Lisinopril for system suitability A CRS
  • MK-521 (dihydrate)
  • isinopriL
  • Lisinopril Dihydrate USP/EP/BP
  • Lisinopril hydrate (MK-521)
  • Lisinopril DihydrateQ: What is Lisinopril Dihydrate Q: What is the CAS Number of Lisinopril Dihydrate Q: What is the storage condition of Lisinopril Dihydrate
  • "Lisinopril for system suitability (Y0001235)"Q: What is "Lisinopril for system suitability (Y0001235)" Q: What is the CAS Number of "Lisinopril for system suitability (Y0001235)"
  • Lisinopril (1368609)
  • Lisinopril
  • Lisinopril diydrate
  • Lisinopril Dihydrate (S)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]-L-proline Dihydrate
  • Lisinopril Dihydrate, ≥ 98.0%
  • Renopril dihydrate
  • Lisinopril dihydrate in methanol
  • Lisinopril dihydrate, ACE inhibitor
  • Lisinopril dihydrate, 10 mM in DMSO
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