2-Piperidinessigs?ure-alpha-phenyl-methylester-hydrochlorid
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- CAS-Nr.
- 298-59-9
- Bezeichnung:
- 2-Piperidinessigs?ure-alpha-phenyl-methylester-hydrochlorid
- Englisch Name:
- Methylphenidate hydrochloride
- Synonyma:
- METHYLPHENIDATE HCL;Concerta;methylphenidate hydrochloride methanol*solution;Equasym;Metadate;Centedin;Centedrin;Centedrine;NSC 169868;Ciba 4311b
- CBNumber:
- CB0188559
- Summenformel:
- C14H20ClNO2
- Molgewicht:
- 269.77
- MOL-Datei:
- 298-59-9.mol
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2-Piperidinessigs?ure-alpha-phenyl-methylester-hydrochlorid Eigenschaften
- Schmelzpunkt:
- 196-198?C
- Flammpunkt:
- 9℃
- storage temp.
- Store at RT
- L?slichkeit
- Freely soluble in water, soluble in ethanol (96 per cent), slightly soluble in methylene chloride.
- Aggregatzustand
- Powder
- pka
- 8.9(at 25℃)
- Wasserl?slichkeit
- Soluble to 50 mM in water and to 100 mM in ethanol
- BCS Class
- 2
- Stabilit?t:
- Stable. Combustible. Incompatible with strong oxidizing agents, alkalies, barbiturates.
- InChI
- InChI=1S/C14H19NO2.ClH/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12;/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3;1H
- InChIKey
- JUMYIBMBTDDLNG-UHFFFAOYSA-N
- SMILES
- C(C(=O)OC)(C1NCCCC1)C1C=CC=CC=1.Cl
- CAS Datenbank
- 298-59-9(CAS DataBase Reference)
- EPA chemische Informationen
- Methylphenidate hydrochloride (298-59-9)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H334 |
Kann bei Einatmen Allergie, asthmaartige Symptome oder Atembeschwerden verursachen. |
Sensibilisierung der Atemwege |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS08.jpg" width="20" height="20" /> |
P261, P285, P304+P341, P342+P311,P501 |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P284 |
Atemschutz tragen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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2-Piperidinessigs?ure-alpha-phenyl-methylester-hydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R42:Sensibilisierung durch Einatmen m?glich.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
white crystalline powder
Verwenden
Controlled substance (stimulant). CNS stimulant. Four isomers of Methylphenidate are known to exist. One pair of threo isomers and one pair of erythro are distinguished, from which only d-threo-Methyl
phenidate exhibits the pharmacologically usually desired effects.
Allgemeine Beschreibung
Odorless white crystalline powder. Metallic taste. Solutions are acid to litmus. Absence of general acid/base catalysis.
Air & Water Reaktionen
Water soluble.
Reaktivit?t anzeigen
Methylphenidate hydrochloride is incompatible with alkalis and solutions of barbiturates . Undergoes typical ester hydrolysis in aqueous solutions at 176°F.
Brandgefahr
Flash point data for Methylphenidate hydrochloride are not available; however, Methylphenidate hydrochloride is probably combustible.
Biologische Aktivit?t
Psychomotor stimulant. Inhibitor of dopamine and noradrenalin transporters that increases the extracellular concentration of dopamine and noradrenalin. Increases locomotor activity in vivo .
2-Piperidinessigs?ure-alpha-phenyl-methylester-hydrochlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
298-59-9(2-Piperidinessigs?ure-alpha-phenyl-methylester-hydrochlorid)Verwandte Suche:
- METHYLPHENIDATE HYDROCHLORIDE
- RITALIN HYDROCHLORIDE
- 2-piperidineaceticacid,alpha-phenyl-,methylester,hydrochloride
- meridilhydrochloride
- 2-Piperidineaceticacid, a-phenyl-, Methyl ester,hydrochloride (1:1)
- Methylphenidate hydrochloride solution
- Ritalin (Methylphenidate Hcl)
- methylalpha-phenyl-2-piperidineacetatehydrochloride
- METHYLPHENIDATE HYDROCHLORIDE--DEA*SCHED
- METHYLPHENIDATE HYDROCHLORIDE(RITALIN HYDROCHLORIDE)
- threo-methyl α-phenyl-α-(2-piperidyl)acetate hydrochloride
- METHYLPHENIDATEHYDROCHLORIDE,USP
- 2-Piperidineacetic acid, a-phenyl-, methyl ester, hydrochloride (6CI, 8CI, 9CI)
- Centedrin
- Centedrine
- Metadate CD
- Methyl a-phenyl-2-piperidineacetate hydrochloride
- NSC 169868
- Ritalin hydrochloride, threo-Methyl α-phenyl-α-(2-piperidyl)acetate hydrochloride
- a-Phenyl-2-piperidineacetic Acid Methyl Ester Hydrochloride
- Ciba 4311b
- Equasym
- Metadate
- Methyl Phenidylacetate Hydrochloride
- Methylphenidan Hydrochloride
- Methyl phenyl(piperidin-2-yl)acetate hydrochloride
- Centedin
- Methylphenidate hydrochloride (ritalin)
- Metilfenidat hydrochloride
- Methylphenidate Hydrochloride (4:1 mixture of DL-erythro and DL-threo)
- Threo-methylphenidate hydrochloride
- Threo-methylα-Phenyl-2-piperidineacetatehydrochloride
- Methylphenidate HCl, 1.0 mg/mL as free base
- Methylphenidate HCl (Racemic mixture)
- Methylphenidate Hydrochloride (CII), USP
- Methylphenidate Hydrochloride CII (125 mg)
- Methylphenidate-d9 HCl
- METHYL 2-PHENYL-2-(PIPERIDIN-2-YL)ACETATE HCL
- JUMYIBMBTDDLNG-UHFFFAOYSA-N
- Methylphenidate(Ritalin)
- Ritalin Impurity 10
- Methyl (2RS)-phenyl[(2RS)-piperidin-2-yl]acetate hydrochloride
- Methylphenidate hydrochloride USP/EP/BP
- Methylphenidate HydrochlorideQ: What is
Methylphenidate Hydrochloride Q: What is the CAS Number of
Methylphenidate Hydrochloride Q: What is the storage condition of
Methylphenidate Hydrochloride Q: What are the applications of
Methylphenidate Hydrochloride
- Methyl (2RS)-phenyl[(2SR)-piperidin-2-yl]acetate Hydrochloride
- METHYLPHENIDATE HCL
- methylphenidate hydrochloride methanol*solution
- Concerta
- Amylmetacresol Impurity 12
- 298-59-9
- C14H19NO2HCl
- C14H19NO2ClH
- Heterocyclic Compounds
- Aromatics
- Intermediates & Fine Chemicals
- Pharmaceuticals
- ASACOL
- 298-59-9
