| Identification | Back Directory | [Name]
(R)-H8-BINAP | [CAS]
139139-86-9 | [Synonyms]
(R)-H8-BINAP
(R)-H8-BINAP >=94%
(R)-(+)-2,2'-Bis(diphenylphospino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl
(R)-(+)-2,2'-Bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl
(R)-(+)-2,2'-Bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl(R)-H8-BINAP
(R)-(+)-2,2μ-Bis(diphenylphospino)-5,5μ,6,6μ,7,7μ,8,8μ-octahydro-1,1μ-binaphthyl, [(1R)-5,5μ,6,6μ,7,7μ,8,8μ-octahydro-[1,1μ-binaphthalene]-2,2μ-diyl]bis[diphenylphosphine] | [Molecular Formula]
C44H40P2 | [MDL Number]
MFCD01630795 | [MOL File]
139139-86-9.mol | [Molecular Weight]
630.748 |
| Chemical Properties | Back Directory | [Melting point ]
207-208°C | [Boiling point ]
745.6±60.0 °C(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [form ]
Powder | [color ]
off-white | [optical activity]
[α]20/D +74°, c = 0.5 in toluene | [CAS DataBase Reference]
139139-86-9 |
| Questions And Answer | Back Directory | [Reaction]
- Biaryl bisphosphine ligand. The H8-BINAP ligand, as the ruthenium complex, catalyzes hydrogenation of unsaturated carboxylic acids to a higher ee than does BINAP.
- The ruthenium catalyzed hydrogenation of aryl propenoic acid to produce the drug Ibuprofen.
- Rhodium catalyzed asymmetric regioselective 1,4-addition of arylboronic acids to 3-substituted maleimides.
- Ligand for palladium-catalyzed enantioselective hydrogenation of substituted indoles.
- Rhodium-catalyzed enantioselective cyclization of γ-alkynylaldehydes with acyl phosphonates.
- Enantioselective synthesis of axially chiral 1-arylisoquinolines by Rh-catalyzed [2+2+2] cycloaddition.
- Enantioselective synthesis of 2,3-disubstituted indolines through Bronsted acid/Pd-complex-promoted tandem reactions.
- Dehydration triggered asymmetric hydrogenation of 3-(α-hydroxyalkyl)indoles
- Iridium-catalyzed [2+2+2] cycloaddition of α,ω-diynes with arylisocyanates
- Asymmetric hydrogenation of 3-(toluenesulfonamidoalkyl)-indoles
- Asymmetric Rh(I)-catalyzed intramolecular [3+2] cycloaddition of 1-yne-vinylcyclopropanes for bicyclo[3.3.0] compounds with a chiral quaternary carbon stereocenter.
- Enantioselective intermolecular [2+2+2] cycloadditions of ene-allenes with allenoates.
- Rh-catalyzed one-pot intermolecular [2+2+2] trimerization/asymmetric intramolecular [4+2] cycloaddition of two aryl ethynyl ethers and 5-alkynals.
- Rh-catalyzed regio-, diastereo-, and enantioselective [2+2+2] cycloaddition of 1,6-enynes with acrylamides.
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| Hazard Information | Back Directory | [Uses]
Catalytic ligand used for:
- Enantioselective synthesis of dihydrobenzofurans and dihydronaphthofurans via olefin isomerization/enantioselective intramolecular Alder-ene reaction of enynes catalyzed by Rh
- Preparation of axially chiral biaryl compounds by gold-catalyzed stereoselective intramolecular hydroarylation
- Preparation of chiral 3-alkyl-substituted indolines by tandem condensation-asymmetric hydrogenation of indoles with aldehydes, catalyzed by Bronsted acids and palladium BINAP complexes
- Stereoselective preparation of hydrindanes and decalins containing up to four contiguous stereocenters via rhodium-catalyzed [2+2+2] cycloaddition of ene-allenes with allenes
- Rhodium-catalyzed asymmetric formal olefination or cycloaddition of 1,3-dicarbonyl compounds with 1,6-diynes or 1,6-enynes
- Stereoselective preparation of 2,3-substituted indolines via Pd-catalyzed hydrogenation of (α-hydroxyalkyl)indoles
| [General Description]
The product is a diphenylphosphinobenzoic acid (DPPBA) based ligand for the palladium-catalyzed asymmetric allylic alkylation with a high degree of enantioselectivity. |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
China Langchem Inc.
|
| Tel: |
0086-21-58956006 |
| Website: |
m.is0513.com/ShowSupplierProductsList19141/0.htm |
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