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ChemicalBook >> CAS DataBase List >> PELITINIB

PELITINIB

PELITINIB price.
  • $40 - $4626
  • Product name: PELITINIB
  • CAS: 257933-82-7
  • MF: C24H23ClFN5O2
  • MW: 467.92
  • EINECS:803-625-4
  • MDL Number:MFCD09837868
  • Synonyms:PELITINIB;2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-, (2E)-;(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide;WAY-EKB 569;(2E)-N-{4-[(3-chloro-4-fluorophenyl)aMino]-3-cyano-7-ethoxyquinolin-6-yl}-4-(diMethylaMino)but-2-enaMide;(E)-N-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide;(2e)-n-(4-((3-chloro-4-fluorophenyl)aMino)-3-cyano-7-ethoxy-6-quinolinyl)-4-(diMethylaMino)-2-butenaMide pelitinib;N-[4-(3-Chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)-2(E)-but·Namide
39 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 25mg
  • 250mg
  • 1000mg
  • 1g
  • 5
  • 25
  • 1mg
  • 5mg
  • 10mg
  • 50MG
  • 100mg
  • 10mM(in 1mL DMSO)
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1141-M001
  • Product descriptionPelitinib ≥95%
  • Packaging1mg
  • Price$86
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX7489
  • Product descriptionPelitinib
  • Packaging100mg
  • Price$267
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA111899
  • Product description(E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide 98+%
  • Packaging5mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA111899
  • Product description(E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide 98+%
  • Packaging10mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA111899
  • Product description(E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide 98+%
  • Packaging100mg
  • Price$282
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0002397
  • Product descriptionPELITINIB 95.00%
  • Packaging5MG
  • Price$233.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0002397
  • Product descriptionPELITINIB 95.00%
  • Packaging50MG
  • Price$2243.59
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1835
  • Product descriptionPelitinib(EKB-569)
  • Packaging10mM(in 1mL DMSO)
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1835
  • Product descriptionPelitinib(EKB-569)
  • Packaging100mg
  • Price$640
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS434625
  • Product description(E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide ≥98%
  • Packaging100mg
  • Price$357
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181080
  • Product descriptionPelitinib (EKB-569; WAY-EKB 569) >98%
  • Packaging100mg
  • Price$542.3
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181080
  • Product descriptionPelitinib (EKB-569; WAY-EKB 569) >98%
  • Packaging250mg
  • Price$986
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181080
  • Product descriptionPelitinib (EKB-569; WAY-EKB 569) >98%
  • Packaging1000mg
  • Price$1802
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFP32643
  • Product descriptionPelitinib
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFP32643
  • Product descriptionPelitinib
  • Packaging50mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15627
  • Product descriptionPelitinib ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1141-M001 Pelitinib ≥95% 1mg $86 2021-12-16 Buy
AK Scientific X7489 Pelitinib 100mg $267 2021-12-16 Buy
Ambeed A111899 (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide 98+% 5mg $40 2021-12-16 Buy
Ambeed A111899 (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide 98+% 10mg $59 2021-12-16 Buy
Ambeed A111899 (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide 98+% 100mg $282 2021-12-16 Buy
American Custom Chemicals Corporation KIN0002397 PELITINIB 95.00% 5MG $233.2 2021-12-16 Buy
American Custom Chemicals Corporation KIN0002397 PELITINIB 95.00% 50MG $2243.59 2021-12-16 Buy
ApexBio Technology A1835 Pelitinib(EKB-569) 10mM(in 1mL DMSO) $105 2021-12-16 Buy
ApexBio Technology A1835 Pelitinib(EKB-569) 100mg $640 2021-12-16 Buy
Arctom AS434625 (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide ≥98% 100mg $357 2021-12-16 Buy
Biorbyt Ltd orb181080 Pelitinib (EKB-569; WAY-EKB 569) >98% 100mg $542.3 2021-12-16 Buy
Biorbyt Ltd orb181080 Pelitinib (EKB-569; WAY-EKB 569) >98% 250mg $986 2021-12-16 Buy
Biorbyt Ltd orb181080 Pelitinib (EKB-569; WAY-EKB 569) >98% 1000mg $1802 2021-12-16 Buy
Biosynth Carbosynth FP32643 Pelitinib 10mg $65 2021-12-16 Buy
Biosynth Carbosynth FP32643 Pelitinib 50mg $150 2021-12-16 Buy
Cayman Chemical 15627 Pelitinib ≥98% 1mg $44 2024-03-01 Buy

Properties

Melting point :173-178°C
Boiling point :655.5±55.0 °C(Predicted)
Density :1.34
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :powder
pka :12.23±0.43(Predicted)
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Pelitinib is a cyanoquinoline that irreversibly inhibits the EGFR receptor tyrosine kinase (IC50 = 39 nM). It inhibits HER2 with a much weaker potency (IC50 = 1.2 μM). By disrupting Akt and MAPK pathways, pelitinib can induce apoptosis and suppress the growth of tumor cell lines, displaying particularly strong efficacy against hepatocellular carcinoma cells (IC50s = ~2 μM).

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