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ChemicalBook >> CAS DataBase List >> 2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone

2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone

2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone price.
  • $44 - $2395.3
  • Product name: 2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone
  • CAS: 371242-69-2
  • MF: C22H19N7O
  • MW: 397.43
  • EINECS:
  • MDL Number:MFCD09970845
  • Synonyms:2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone;IC-87114;IC-87114 (IC87114);4(3H)-Quinazolinone, 2-[(6-aMino-9H-purin-9-yl)Methyl]-5-Methyl-3-(2-Methylphenyl)-;IC87114 (PI3-K delta inhibitor);2-((6-AMINO-9H-PURIN-9-YL)METHYL)-5-METHYL-3-O-TOLYLQUINAZOLIN-4(3H)-ONE;2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone IC-87114;IC-87114 (PIK-293)
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  • Adipogen Life Sciences
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
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  • 5mg
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  • 50mg
  • 100mg
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  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1045-M005
  • Product descriptionIC87114 ≥95%
  • Packaging5mg
  • Price$97
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1045-M100
  • Product descriptionIC87114 ≥95%
  • Packaging100mg
  • Price$1075
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1045
  • Product descriptionIC87114
  • Packaging1mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2065
  • Product descriptionIC-87114
  • Packaging5mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60152
  • Product descriptionIC-87114 ≥98%
  • Packaging10mg
  • Price$188
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2168
  • Product descriptionIC87114 98%
  • Packaging5mg
  • Price$93.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2168
  • Product descriptionIC87114 98%
  • Packaging25mg
  • Price$324.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181021
  • Product descriptionIC-87114 >98%
  • Packaging100mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181021
  • Product descriptionIC-87114 >98%
  • Packaging250mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181021
  • Product descriptionIC-87114 >98%
  • Packaging1000mg
  • Price$2395.3
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA43322
  • Product descriptionIC 87114
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA43322
  • Product descriptionIC 87114
  • Packaging50mg
  • Price$297.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11589
  • Product descriptionIC-87114 ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11589
  • Product descriptionIC-87114 ≥98%
  • Packaging5mg
  • Price$97
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11589
  • Product descriptionIC-87114 ≥98%
  • Packaging10mg
  • Price$172
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11589
  • Product descriptionIC-87114 ≥98%
  • Packaging50mg
  • Price$745
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1045-M005 IC87114 ≥95% 5mg $97 2021-12-16 Buy
Adipogen Life Sciences SYN-1045-M100 IC87114 ≥95% 100mg $1075 2021-12-16 Buy
AK Scientific SYN1045 IC87114 1mg $80 2021-12-16 Buy
ApexBio Technology A2065 IC-87114 5mg $59 2021-12-16 Buy
Arctom CFN60152 IC-87114 ≥98% 10mg $188 2021-12-16 Buy
Axon Medchem Axon2168 IC87114 98% 5mg $93.5 2021-12-16 Buy
Axon Medchem Axon2168 IC87114 98% 25mg $324.5 2021-12-16 Buy
Biorbyt Ltd orb181021 IC-87114 >98% 100mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb181021 IC-87114 >98% 250mg $1208.7 2021-12-16 Buy
Biorbyt Ltd orb181021 IC-87114 >98% 1000mg $2395.3 2021-12-16 Buy
Biosynth Carbosynth FA43322 IC 87114 10mg $85 2021-12-16 Buy
Biosynth Carbosynth FA43322 IC 87114 50mg $297.5 2021-12-16 Buy
Cayman Chemical 11589 IC-87114 ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 11589 IC-87114 ≥98% 5mg $97 2024-03-01 Buy
Cayman Chemical 11589 IC-87114 ≥98% 10mg $172 2024-03-01 Buy
Cayman Chemical 11589 IC-87114 ≥98% 50mg $745 2024-03-01 Buy

Properties

Boiling point :673.7±65.0 °C(Predicted)
Density :1.43
storage temp. :Store at -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥6.62 mg/mL in DMF
form :White powder solid.
pka :3.90±0.10(Predicted)
color :White to gray
CAS DataBase Reference :371242-69-2

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

IC-87114 is a selective PI3Kδ inhibitor with IC50 of 0.5 μM in a cell-free assay, 58-fold more selective for PI3Kδ than PI3Kγ, and over 100-fold more selective than PI3Kα/β.