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ChemicalBook >> CAS DataBase List >> N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE

N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE

N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE price.
  • $49 - $1900
  • Product name: N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE
  • CAS: 853625-60-2
  • MF: C24H20N4O4S
  • MW: 460.51
  • EINECS:
  • MDL Number:MFCD10687099
  • Synonyms:N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE;SECINH3;N-(4-(5-(benzo[d][1,3]dioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl)phenyl)-2-(phenylthio)acetamide;3]dioxol-5-yl)-3-methoxy-1H-1;4-triazol-1-yl)phenyl)-2-(phenylthio)acetamide;N-(4-(5-(benzo[d][1;CS-2379;Acetamide, N-[4-[5-(1,3-benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)-
15 prices
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Brand
  • AK Scientific
  • Ambeed
  • Cayman Chemical
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 5mg
  • 5
  • 1mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number3811CE
  • Product descriptionSecinH3
  • Packaging5mg
  • Price$257
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA923399
  • Product descriptionSecinH3 98+%
  • Packaging5mg
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA923399
  • Product descriptionSecinH3 98+%
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA923399
  • Product descriptionSecinH3 98+%
  • Packaging25mg
  • Price$124
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA923399
  • Product descriptionSecinH3 98+%
  • Packaging50mg
  • Price$162
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009570
  • Product descriptionSecinH3 ≥98%
  • Packaging1mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009570
  • Product descriptionSecinH3 ≥98%
  • Packaging5mg
  • Price$143
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009570
  • Product descriptionSecinH3 ≥98%
  • Packaging10mg
  • Price$238
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009570
  • Product descriptionSecinH3 ≥98%
  • Packaging25mg
  • Price$475
  • Updated2024-03-01
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8424
  • Product descriptionSecinH3 >98%
  • Packaging100mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8424
  • Product descriptionSecinH3 >98%
  • Packaging250mg
  • Price$1000
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8424
  • Product descriptionSecinH3 >98%
  • Packaging1g
  • Price$1900
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number565725-M
  • Product descriptionSecinH3 - CAS 853625-60-2 - Calbiochem A cell-permeable triazolo compound that acts as a Sec7 domain-binding, selective antagonist against cytohesin family small GEFs.
  • Packaging5MG
  • Price$282
  • Updated2023-06-20
  • Buy
  • ManufacturerTocris
  • Product number2849
  • Product descriptionSecinH3 ≥98%(HPLC)
  • Packaging5
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberS241013
  • Product descriptionSecinH3
  • Packaging50mg
  • Price$960
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3811CE SecinH3 5mg $257 2021-12-16 Buy
Ambeed A923399 SecinH3 98+% 5mg $73 2021-12-16 Buy
Ambeed A923399 SecinH3 98+% 10mg $95 2021-12-16 Buy
Ambeed A923399 SecinH3 98+% 25mg $124 2021-12-16 Buy
Ambeed A923399 SecinH3 98+% 50mg $162 2021-12-16 Buy
Cayman Chemical 10009570 SecinH3 ≥98% 1mg $49 2024-03-01 Buy
Cayman Chemical 10009570 SecinH3 ≥98% 5mg $143 2024-03-01 Buy
Cayman Chemical 10009570 SecinH3 ≥98% 10mg $238 2024-03-01 Buy
Cayman Chemical 10009570 SecinH3 ≥98% 25mg $475 2024-03-01 Buy
DC Chemicals DC8424 SecinH3 >98% 100mg $600 2021-12-16 Buy
DC Chemicals DC8424 SecinH3 >98% 250mg $1000 2021-12-16 Buy
DC Chemicals DC8424 SecinH3 >98% 1g $1900 2021-12-16 Buy
Sigma-Aldrich 565725-M SecinH3 - CAS 853625-60-2 - Calbiochem A cell-permeable triazolo compound that acts as a Sec7 domain-binding, selective antagonist against cytohesin family small GEFs. 5MG $282 2023-06-20 Buy
Tocris 2849 SecinH3 ≥98%(HPLC) 5 $99 2021-12-16 Buy
TRC S241013 SecinH3 50mg $960 2021-12-16 Buy

Properties

storage temp. :Inert atmosphere,2-8°C
solubility :DMF: 30 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 25 mg/ml; Ethanol: 0.3 mg/ml
form :White powder solid.
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

SecinH3 is a cell-permeable triazolo compound that acts as a Sec7 domain-binding (Kd ≤250 nM for Sec7 from human cytohesins 1-3), selective antagonist against cytohesin family small nucleotide exchange factors, or GEFs (IC50 ≤5.6 μM in ARF1 GDP/GTP exchange assays using human cytohesin 3, as well as murine and Drosophila homologues). SecinH3 inhibits large GEFs only at much higher concentrations (IC50 ≥65 μM in GDP/GTP exchange assays using hEFA6-S7 and yGea2-S7) and exhibits little activity against a panel of 10 commonly studied kinases or hSosII. SecinH3 was shown to effectively inhibit insulin signaling both in HepG2 cells in vitro and in Drosophila and mice in vivo. SecinH3 is an inhibitor of cytohesin-1, cytohesin-2 and GRP1.

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