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ChemicalBook >> CAS DataBase List >> Panobinostat

Panobinostat

Panobinostat price.
  • $28 - $4735.5
  • Product name: Panobinostat
  • CAS: 404950-80-7
  • MF: C21H23N3O2
  • MW: 349.43
  • EINECS:803-814-1
  • MDL Number:MFCD09833242
  • Synonyms:(E)-N-HYDROXY-3-(4-{[2-(2-METHYL-1H-INDOL-3-YL)-ETHYLAMINO]-METHYL}-PHENYL)-ACRYLAMIDE;N-Hydroxy-3-[4-[2-(2-methyl-1H-indol-3-yl)ethylaminomethyl]phenyl]-2(E)-propenamide;LBH-589/Panobinostat;LBH-589;PANOBINOSTAT;2-Propenamide, N-hydroxy-3-(4-(((2-(2-methyl-1H-indol-3-yl)ethyl)amino)methyl)phenyl)-, (2E)-;NVP-LBH589;Panobinostat (LBH589)
34 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
  • Usbiological
Package
  • 1unit
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500MG
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product numberSYN5746
  • Product descriptionLBH-589
  • Packaging10mg
  • Price$142
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0045863
  • Product descriptionLBH-589 95.00%
  • Packaging500MG
  • Price$4735.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8178
  • Product descriptionPanobinostat(LBH589)
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8178
  • Product descriptionPanobinostat(LBH589)
  • Packaging10mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8178
  • Product descriptionPanobinostat(LBH589)
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8178
  • Product descriptionPanobinostat(LBH589)
  • Packaging50mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8178
  • Product descriptionPanobinostat(LBH589)
  • Packaging200mg
  • Price$270
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8178
  • Product descriptionPanobinostat(LBH589)
  • Packaging500mg
  • Price$440
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60033
  • Product descriptionPanobinostat(LBH589)
  • Packaging10mg
  • Price$118
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1548
  • Product descriptionLBH589-NVP-LBH589|Panobinostat 98%
  • Packaging10mg
  • Price$104.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546003
  • Product descriptionPanobinostat >98%
  • Packaging5mg
  • Price$173.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546003
  • Product descriptionPanobinostat >98%
  • Packaging25mg
  • Price$455.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181045
  • Product descriptionPanobinostat(LBH589) >98%
  • Packaging100mg
  • Price$606.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181045
  • Product descriptionPanobinostat(LBH589) >98%
  • Packaging250mg
  • Price$912.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181045
  • Product descriptionPanobinostat(LBH589) >98%
  • Packaging1g
  • Price$1802
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFH26749
  • Product descriptionPanobinostat
  • Packaging100mg
  • Price$150
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5746 LBH-589 10mg $142 2021-12-16 Buy
American Custom Chemicals Corporation API0045863 LBH-589 95.00% 500MG $4735.5 2021-12-16 Buy
ApexBio Technology A8178 Panobinostat(LBH589) 1unit $28 2021-12-16 Buy
ApexBio Technology A8178 Panobinostat(LBH589) 10mg $60 2021-12-16 Buy
ApexBio Technology A8178 Panobinostat(LBH589) 10mM(in 1mL DMSO) $60 2021-12-16 Buy
ApexBio Technology A8178 Panobinostat(LBH589) 50mg $120 2021-12-16 Buy
ApexBio Technology A8178 Panobinostat(LBH589) 200mg $270 2021-12-16 Buy
ApexBio Technology A8178 Panobinostat(LBH589) 500mg $440 2021-12-16 Buy
Arctom CFN60033 Panobinostat(LBH589) 10mg $118 2021-12-16 Buy
Axon Medchem Axon1548 LBH589-NVP-LBH589|Panobinostat 98% 10mg $104.5 2021-12-16 Buy
Biorbyt Ltd orb546003 Panobinostat >98% 5mg $173.4 2021-12-16 Buy
Biorbyt Ltd orb546003 Panobinostat >98% 25mg $455.6 2021-12-16 Buy
Biorbyt Ltd orb181045 Panobinostat(LBH589) >98% 100mg $606.9 2021-12-16 Buy
Biorbyt Ltd orb181045 Panobinostat(LBH589) >98% 250mg $912.9 2021-12-16 Buy
Biorbyt Ltd orb181045 Panobinostat(LBH589) >98% 1g $1802 2021-12-16 Buy
Biosynth Carbosynth FH26749 Panobinostat 100mg $150 2021-12-16 Buy

Properties

Melting point :114-117?C
Density :1.241±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under Inert Atmosphere
solubility :Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
form :solid
pka :8.71±0.23(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Panobinostat is a potent inhibitor of all histone deacetylases (HDACs), with Ki values ranging from 0.6 to 31 nM for HDAC1-11. Through this action, it leads to acetylation of a range of cellular proteins, resulting in cell cycle arrest and apoptosis in cancer cells. It has potential applications in several different forms of cancer as well as in spinal muscular atrophy and HIV therapy.