Chidamide
- $39 - $1290
- Product name: Chidamide
- CAS: 743420-02-2
- MF: C22H19FN4O2
- MW: 390.41
- EINECS:
- MDL Number:
- Synonyms:(E)-N-(2-amino-5-fluorophenyl)-4-((3-(pyridin-3-yl)acrylamido)methyl)benzamide Chidamide;Chidamide;(E)-N-(2-aMino-5-fluorophenyl)-4-((3-(pyridin-3-yl)acrylaMido)Methyl)benzaMide;N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propenyl]amino]methyl]benzamide;De-4-fluoro 5-Fluoro Chidamide;CHIDAMIDE;(E)-N-(2-AMINO-5-FLUOROPHENYL)-4-((3-(PYRIDIN-3-YL)ACRYLAMIDO)METHYL)BENZAMIDE;(E)-N-(2-AMINO-5-FLUOROPHENYL)-4-((3-(PYRIDIN-3-YL)ACRYLAMIDO)METHYL)BENZAMIDE CHIDAMIDE;N-(2-AMINO-5-FLUOROPHENYL)-4-[[[1-OXO-3-(3-PYRIDINYL)-2-PROPENYL]AMINO]METHYL;N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propenyl]amino]methyl;Chidamide D4
26 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- AvaChem
- Cayman Chemical
- Chemenu
- ChemScene
- TRC
- Usbiological
Package
- 10mM(in 1mL DMSO)
- 1MG
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- ManufacturerAK Scientific
- Product number1671AH
- Product descriptionChidamide
- Packaging25mg
- Price$395
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA186722
- Product descriptionChidamide 98+%
- Packaging5mg
- Price$163
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA186722
- Product descriptionChidamide 98+%
- Packaging10mg
- Price$276
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA186722
- Product descriptionChidamide 98+%
- Packaging25mg
- Price$469
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0105894
- Product descriptionN-(2-AMINO-5-FLUOROPHENYL)-4-(((1-OXO-3-(3-PYRIDINYL)-2-PROPEN-1-YL)AMINO)METHYL)-BENZAMIDE 95.00%
- Packaging1MG
- Price$153.3
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5916
- Product descriptionChidamide
- Packaging2mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5916
- Product descriptionChidamide
- Packaging5mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5916
- Product descriptionChidamide
- Packaging10mM(in 1mL DMSO)
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5916
- Product descriptionChidamide
- Packaging10mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5916
- Product descriptionChidamide
- Packaging50mg
- Price$960
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3007
- Product descriptionChidamide
- Packaging5mg
- Price$129
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3007
- Product descriptionChidamide
- Packaging25mg
- Price$449
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3007
- Product descriptionChidamide
- Packaging100mg
- Price$1290
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13686
- Product descriptionChidamide ≥98%
- Packaging1mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13686
- Product descriptionChidamide ≥98%
- Packaging5mg
- Price$166
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13686
- Product descriptionChidamide ≥98%
- Packaging10mg
- Price$293
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 1671AH | Chidamide | 25mg | $395 | 2021-12-16 | Buy |
Ambeed | A186722 | Chidamide 98+% | 5mg | $163 | 2021-12-16 | Buy |
Ambeed | A186722 | Chidamide 98+% | 10mg | $276 | 2021-12-16 | Buy |
Ambeed | A186722 | Chidamide 98+% | 25mg | $469 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | HCH0105894 | N-(2-AMINO-5-FLUOROPHENYL)-4-(((1-OXO-3-(3-PYRIDINYL)-2-PROPEN-1-YL)AMINO)METHYL)-BENZAMIDE 95.00% | 1MG | $153.3 | 2021-12-16 | Buy |
ApexBio Technology | B5916 | Chidamide | 2mg | $80 | 2021-12-16 | Buy |
ApexBio Technology | B5916 | Chidamide | 5mg | $140 | 2021-12-16 | Buy |
ApexBio Technology | B5916 | Chidamide | 10mM(in 1mL DMSO) | $170 | 2021-12-16 | Buy |
ApexBio Technology | B5916 | Chidamide | 10mg | $240 | 2021-12-16 | Buy |
ApexBio Technology | B5916 | Chidamide | 50mg | $960 | 2021-12-16 | Buy |
AvaChem | 3007 | Chidamide | 5mg | $129 | 2021-12-16 | Buy |
AvaChem | 3007 | Chidamide | 25mg | $449 | 2021-12-16 | Buy |
AvaChem | 3007 | Chidamide | 100mg | $1290 | 2021-12-16 | Buy |
Cayman Chemical | 13686 | Chidamide ≥98% | 1mg | $39 | 2021-12-16 | Buy |
Cayman Chemical | 13686 | Chidamide ≥98% | 5mg | $166 | 2021-12-16 | Buy |
Cayman Chemical | 13686 | Chidamide ≥98% | 10mg | $293 | 2021-12-16 | Buy |
Properties
Melting point :>145°C (dec.)
Boiling point :600.2±55.0 °C(Predicted)
Density :1.336±0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
form :Solid
pka :12.30±0.70(Predicted)
color :Off-White to Pale Beige
Boiling point :600.2±55.0 °C(Predicted)
Density :1.336±0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
form :Solid
pka :12.30±0.70(Predicted)
color :Off-White to Pale Beige
Safety Information
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Description
Chidamide is a histone deacetylase inhibitor that increases histone H3 acetylation levels in LoVo and HT-29 colon cancer cells at concentrations as low as 4 μM. Additionally, chidamide affects the activation of oncogenic signaling kinases by dose-dependently reducing phosphorylated Akt, mTOR, p70S6k, Raf, and Erk1/2 protein expression in colon cancer cells. Furthermore, chidamide treatment dose-dependently upregulates p21 protein expression, downregulates Cdk4, and induces cell cycle arrest at the G0/G1 phase.Related product price
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