Sivelestat sodium
- $45 - $3698
- Product name: Sivelestat sodium
- CAS: 201677-61-4
- MF: C20H25N2NaO8S
- MW: 476.48
- EINECS:
- MDL Number:MFCD01937969
- Synonyms:SIVELESTAT SODIUM HYDRATE;SIVELESTAT SODIUM TETRAHYDRATE;n-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(s)-glycine monosodium salt tetrahydrate;Sivelestat sodium;N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-Glycine monosodium salt tetrahydrate;Sivelestat(anhydrous);Glycine, N-[2-[[[4-(2,2-diMethyl-1-oxopropoxy)phenyl]sulfonyl]aMino]benzoyl]-, MonosodiuM salt, tetrahydrate;sodium,2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetate,tetrahydrate
29 prices
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Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Arctom
- Ark Pharm
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberJ98651
- Product descriptionSivelestatsodiumtetrahydrate
- Packaging50mg
- Price$249
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA274870
- Product descriptionSivelestatsodiumtetrahydrate 98+%
- Packaging5mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA274870
- Product descriptionSivelestatsodiumtetrahydrate 98+%
- Packaging10mg
- Price$86
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA274870
- Product descriptionSivelestatsodiumtetrahydrate 98+%
- Packaging50mg
- Price$287
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA274870
- Product descriptionSivelestatsodiumtetrahydrate 98+%
- Packaging100mg
- Price$435
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA274870
- Product descriptionSivelestatsodiumtetrahydrate 98+%
- Packaging1g
- Price$3698
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008936
- Product descriptionSIVELESTAT SODIUM HYDRATE 97.00%
- Packaging5MG
- Price$217.8
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008936
- Product descriptionSIVELESTAT SODIUM HYDRATE 97.00%
- Packaging1G
- Price$2073.23
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS503289
- Product descriptionSivelestatsodiumtetrahydrate ≥98%
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS503289
- Product descriptionSivelestatsodiumtetrahydrate ≥98%
- Packaging10mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS503289
- Product descriptionSivelestatsodiumtetrahydrate ≥98%
- Packaging50mg
- Price$284
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS503289
- Product descriptionSivelestatsodiumtetrahydrate ≥98%
- Packaging100mg
- Price$431
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberAK546607
- Product descriptionSivelestatsodiumtetrahydrate 98+%
- Packaging50mg
- Price$349
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17779
- Product descriptionSivelestat (sodium salt hydrate) ≥98%
- Packaging5mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17779
- Product descriptionSivelestat (sodium salt hydrate) ≥98%
- Packaging10mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17779
- Product descriptionSivelestat (sodium salt hydrate) ≥98%
- Packaging25mg
- Price$254
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | J98651 | Sivelestatsodiumtetrahydrate | 50mg | $249 | 2021-12-16 | Buy |
Ambeed | A274870 | Sivelestatsodiumtetrahydrate 98+% | 5mg | $51 | 2021-12-16 | Buy |
Ambeed | A274870 | Sivelestatsodiumtetrahydrate 98+% | 10mg | $86 | 2021-12-16 | Buy |
Ambeed | A274870 | Sivelestatsodiumtetrahydrate 98+% | 50mg | $287 | 2021-12-16 | Buy |
Ambeed | A274870 | Sivelestatsodiumtetrahydrate 98+% | 100mg | $435 | 2021-12-16 | Buy |
Ambeed | A274870 | Sivelestatsodiumtetrahydrate 98+% | 1g | $3698 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0008936 | SIVELESTAT SODIUM HYDRATE 97.00% | 5MG | $217.8 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0008936 | SIVELESTAT SODIUM HYDRATE 97.00% | 1G | $2073.23 | 2021-12-16 | Buy |
Arctom | AS503289 | Sivelestatsodiumtetrahydrate ≥98% | 5mg | $50 | 2021-12-16 | Buy |
Arctom | AS503289 | Sivelestatsodiumtetrahydrate ≥98% | 10mg | $85 | 2021-12-16 | Buy |
Arctom | AS503289 | Sivelestatsodiumtetrahydrate ≥98% | 50mg | $284 | 2021-12-16 | Buy |
Arctom | AS503289 | Sivelestatsodiumtetrahydrate ≥98% | 100mg | $431 | 2021-12-16 | Buy |
Ark Pharm | AK546607 | Sivelestatsodiumtetrahydrate 98+% | 50mg | $349 | 2021-12-16 | Buy |
Cayman Chemical | 17779 | Sivelestat (sodium salt hydrate) ≥98% | 5mg | $62 | 2024-03-01 | Buy |
Cayman Chemical | 17779 | Sivelestat (sodium salt hydrate) ≥98% | 10mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 17779 | Sivelestat (sodium salt hydrate) ≥98% | 25mg | $254 | 2024-03-01 | Buy |
Properties
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 20 mg/ml).
form :White solid.
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
CAS DataBase Reference :201677-61-4(CAS DataBase Reference)
solubility :Soluble in DMSO (up to 20 mg/ml).
form :White solid.
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
CAS DataBase Reference :201677-61-4(CAS DataBase Reference)
Safety Information
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Description
Sivelestat sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase (HNE) (IC50 = 44 nM, Ki = 0.2 M). Sivelestat sodium tetrahydrate also effectively inhibits leukocyte elastase derived from hamster, mouse, rabbit and rat (IC50 = 19 to 49 nM). Sivelestat sodium tetrahydrate, even at concentrations of 100 M, does not inhibit plasma kallikrein, plasmin, thrombin, trypsin, pancreas kallikrein, chymotrypsin and cathepsin G. In in-vivo studies, sivelestat sodium tetrahydrate suppressed lung hemorrhage in hamster (ID50 = 82 g/kg) by intratracheal administration and increased skin capillary permeability in guinea pigs (ID50 = 9.6 mg/kg) by intravenous administration, both of which were induced by human neutrophil elastase.More related product prices
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