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ChemicalBook >> CAS DataBase List >> Dacomitinib (PF299804)

Dacomitinib (PF299804)

Dacomitinib (PF299804) price.
  • $28 - $1703
  • Product name: Dacomitinib (PF299804)
  • CAS: 1110813-31-4
  • MF: C24H25ClFN5O2
  • MW: 469.94
  • EINECS:-0
  • MDL Number:MFCD19443734
  • Synonyms:PF-00299804-03;PF-00299804;DacoMitinib (PF-00299804);DacoMitinib,PF299804;DacoMitinib (PF299804,PF-00299804);PF299804;DACOMITINIB;DacoMitinib (PF299804, PF299);(E)-N-(4-((3-chloro-4-fluorophenyl)aMino)-7-Methoxyquizolin-6-yl)-4-(piperidin-1-yl)but-2-eMide
34 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • TCI Chemical
  • Tocris
  • TRC
Package
  • 1MG
  • 1unit
  • 5MG
  • 10mg
  • 50mg
  • 100mg
  • 200mg
  • 50
  • 500mg
  • 2g
  • 5g
  • 250mg
  • 1g
  • 10
  • 10mM(in 1mL DMSO)
  • 25g
  • ManufacturerAK Scientific
  • Product numberY0338
  • Product descriptionDacomitinib
  • Packaging25g
  • Price$1703
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000466
  • Product descriptionPF-00299804 95.00%
  • Packaging1MG
  • Price$148.05
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000466
  • Product descriptionPF-00299804 95.00%
  • Packaging5MG
  • Price$499.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8319
  • Product descriptionDacomitinib(PF299804,PF299)
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8319
  • Product descriptionDacomitinib(PF299804,PF299)
  • Packaging10mM(in 1mL DMSO)
  • Price$102
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60084
  • Product descriptionDacomitinib(PF-00299804) ≥98%
  • Packaging10mg
  • Price$118
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154623
  • Product descriptionPF-299804 (Dacomitinib,PF-00299804) >99%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154623
  • Product descriptionPF-299804 (Dacomitinib,PF-00299804) >99%
  • Packaging250mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154623
  • Product descriptionPF-299804 (Dacomitinib,PF-00299804) >99%
  • Packaging1g
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD64992
  • Product descriptionDacomitinib
  • Packaging10mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD64992
  • Product descriptionDacomitinib
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number9001879
  • Product descriptionPF-299804 ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number9001879
  • Product descriptionPF-299804 ≥98%
  • Packaging5mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number9001879
  • Product descriptionPF-299804 ≥98%
  • Packaging10mg
  • Price$341
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number9001879
  • Product descriptionPF-299804 ≥98%
  • Packaging50mg
  • Price$1062
  • Updated2024-03-01
  • Buy
  • ManufacturerChem-Impex
  • Product number37832
  • Product descriptionDacomitinib,98%(HPLC) 98%(HPLC)
  • Packaging50MG
  • Price$162.4
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0338 Dacomitinib 25g $1703 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000466 PF-00299804 95.00% 1MG $148.05 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000466 PF-00299804 95.00% 5MG $499.5 2021-12-16 Buy
ApexBio Technology A8319 Dacomitinib(PF299804,PF299) 1unit $28 2021-12-16 Buy
ApexBio Technology A8319 Dacomitinib(PF299804,PF299) 10mM(in 1mL DMSO) $102 2021-12-16 Buy
Arctom CFN60084 Dacomitinib(PF-00299804) ≥98% 10mg $118 2021-12-16 Buy
Biorbyt Ltd orb154623 PF-299804 (Dacomitinib,PF-00299804) >99% 100mg $510 2021-12-16 Buy
Biorbyt Ltd orb154623 PF-299804 (Dacomitinib,PF-00299804) >99% 250mg $765 2021-12-16 Buy
Biorbyt Ltd orb154623 PF-299804 (Dacomitinib,PF-00299804) >99% 1g $1504.5 2021-12-16 Buy
Biosynth Carbosynth FD64992 Dacomitinib 10mg $125 2021-12-16 Buy
Biosynth Carbosynth FD64992 Dacomitinib 50mg $250 2021-12-16 Buy
Cayman Chemical 9001879 PF-299804 ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 9001879 PF-299804 ≥98% 5mg $193 2024-03-01 Buy
Cayman Chemical 9001879 PF-299804 ≥98% 10mg $341 2024-03-01 Buy
Cayman Chemical 9001879 PF-299804 ≥98% 50mg $1062 2024-03-01 Buy
Chem-Impex 37832 Dacomitinib,98%(HPLC) 98%(HPLC) 50MG $162.4 2021-12-16 Buy

Properties

Melting point :184-187°C
Boiling point :665.7±55.0 °C(Predicted)
Density :1.344
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
form :White solid.
pka :12.05±0.43(Predicted)
color :White to Pale Yellow
InChIKey :LVXJQMNHJWSHET-AATRIKPKSA-N
SMILES :C(NC1C(OC)=CC2C(C=1)=C(NC1=CC=C(F)C(Cl)=C1)N=CN=2)(=O)/C=C/CN1CCCCC1
CAS DataBase Reference :1110813-31-4

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Dacomitinib is a selective and irreversible inhibitor of EGFR. It is a drug candidate for the treatment of non-small cell lung carcinoma. It is current under the Phase III clinical trials. It also shows potential for the treatment of HER-2 amplified breast cancer cells lines that are resistant to trastuzumab and lapatinib. 

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