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ChemicalBook >> CAS DataBase List >> Olmutinib

Olmutinib

Olmutinib price.
  • $32 - $850
  • Product name: Olmutinib
  • CAS: 1353550-13-6
  • MF: C26H26N6O2S
  • MW: 486.59
  • EINECS:-0
  • MDL Number:
  • Synonyms:HM71224;HM-71224;Olmutinib;Olmutinib, HM71224;N-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide dihydrochloride monohydrate;N-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide;N-[3-[[2-[[4-(4-Methyl-1-piperazinyl)phenyl]amino]thieno[3,2-d]pyrimidin-4-yl]oxy]phenyl]-2-propenamide;HM71224, Olmutinib
17 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number2858DM
  • Product descriptionOlmutinib
  • Packaging10mg
  • Price$370
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7813
  • Product descriptionOlmutinib(HM61713,BI1482694)
  • Packaging100mg
  • Price$780
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19481
  • Product descriptionHM71224 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19481
  • Product descriptionHM71224 ≥98%
  • Packaging5mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19481
  • Product descriptionHM71224 ≥98%
  • Packaging10mg
  • Price$243
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19481
  • Product descriptionHM71224 ≥98%
  • Packaging25mg
  • Price$533
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5413
  • Product descriptionOlmutinib 99.99%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5413
  • Product descriptionOlmutinib 99.99%
  • Packaging10mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5413
  • Product descriptionOlmutinib 99.99%
  • Packaging50mg
  • Price$216
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5413
  • Product descriptionOlmutinib 99.99%
  • Packaging100mg
  • Price$336
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5413
  • Product descriptionOlmutinib 99.99%
  • Packaging200mg
  • Price$540
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003771
  • Product descriptionOlmutinib 98+%
  • Packaging50mg
  • Price$393
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003771
  • Product descriptionOlmutinib 98+%
  • Packaging100mg
  • Price$539
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003771
  • Product descriptionOlmutinib 98+%
  • Packaging250mg
  • Price$850
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8819
  • Product descriptionHM-61713(BI-1482694) >98%
  • Packaging100mg
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number110630
  • Product descriptionOlmutinib
  • Packaging200mg
  • Price$490
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2858DM Olmutinib 10mg $370 2021-12-16 Buy
ApexBio Technology B7813 Olmutinib(HM61713,BI1482694) 100mg $780 2021-12-16 Buy
Cayman Chemical 19481 HM71224 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 19481 HM71224 ≥98% 5mg $139 2024-03-01 Buy
Cayman Chemical 19481 HM71224 ≥98% 10mg $243 2024-03-01 Buy
Cayman Chemical 19481 HM71224 ≥98% 25mg $533 2024-03-01 Buy
ChemScene CS-5413 Olmutinib 99.99% 5mg $60 2021-12-16 Buy
ChemScene CS-5413 Olmutinib 99.99% 10mg $96 2021-12-16 Buy
ChemScene CS-5413 Olmutinib 99.99% 50mg $216 2021-12-16 Buy
ChemScene CS-5413 Olmutinib 99.99% 100mg $336 2021-12-16 Buy
ChemScene CS-5413 Olmutinib 99.99% 200mg $540 2021-12-16 Buy
Crysdot CD31003771 Olmutinib 98+% 50mg $393 2021-12-16 Buy
Crysdot CD31003771 Olmutinib 98+% 100mg $539 2021-12-16 Buy
Crysdot CD31003771 Olmutinib 98+% 250mg $850 2021-12-16 Buy
DC Chemicals DC8819 HM-61713(BI-1482694) >98% 100mg $380 2021-12-16 Buy
Medical Isotopes, Inc. 110630 Olmutinib 200mg $490 2021-12-16 Buy

Properties

Density :1.336±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥9.11 mg/mL in EtOH with ultrasonic; ≥96.6 mg/mL in DMSO
form :crystalline solid
pka :12.87±0.70(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

HM71224 is an inhibitor of Bruton's tyrosine kinase (BTK; IC50 = 1.95 nM) that has been shown to prevent B cell activation and osteoclastogenesis. It additionally targets the related kinases BMX, Tec, and TXK (IC50s = 0.64, 4.57, and 4.62 nM, respectively), as well as EGFR (IC50 = 4.96 nM). In a mouse model of rheumatoid arthritis, 3-30 mg/kg HM71224 dose dependently reduced erosive bone changes and prevented bone loss.

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