5,7-Dihydroxy-3-p-methoxyphenyl-4H-chromen-4-on Chemische Eigenschaften,Einsatz,Produktion Methoden

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Beschreibung

Biochanin A is a natural isoflavone with diverse biological actions, most notably as a phytoestrogen. It can affect hormone levels by inhibiting 5α-reductase and 17β-hydroxysteroid dehydrogenase or altering aromatase (CYP19A1) activity. Also known as 4’-methyl genistein, biochanin A can be metabolized in vivo to genistein , another phytoestrogen with diverse effects. Biochanin A also intersects with signaling through peroxisome proliferator-activated receptors (PPARs), as it activates PPARγ (EC₅₀ = 19 μM) and has also been shown to activate a PPARα promoter. Moreover, it increases the expression of the PPARγ coactivator PGC-1α, promoting mitochondrial biogenesis. Biochanin A also inhibits fatty acid amide hydrolase (IC₅₀ = 2.4 μM) and acts as an agonist of the aryl hydrocarbon receptor (EC₅₀ = 0.25 μM).

Chemische Eigenschaften

Off-White Solid

Verwenden

An isoflavone with anticancer proliferation, differentiation and chemopreventitive properties. Inhibits metabolic activation of benzo[a]pyrene

Allgemeine Beschreibung

Biochanin A (BCA) is synthesized in vitro from phloroglucinol. A series of steps involving Friedel?Crafts reaction results in an intermediate product 1-(2,4,6-trihydroxyphenyl)-2-(4 methoxyphenyl) ethanone, which post cyclization leads to BCA. It is catabolized to isoflavone genistein post ingestion.

5,7-Dihydroxy-3-p-methoxyphenyl-4H-chromen-4-on Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

5,7-Dihydroxy-3-p-methoxyphenyl-4H-chromen-4-on Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shaanxi Dideu Medichem Co. Ltd	18192627656	1012@dideu.com	China	3003	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	18751	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
Nanjing Finetech Chemical Co., Ltd.	025-85710122 17714198479	sales@fine-chemtech.com	CHINA	885	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32956	60
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58
Shaanxi Yikanglong Biotechnology Co., Ltd.	17791478691	yklbiotech@163.com	CHINA	296	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3772	58

491-80-5(5,7-Dihydroxy-3-p-methoxyphenyl-4H-chromen-4-on)Verwandte Suche:

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• 5,7-DIHYDROXY-4''-METHOXYISOFLAVONE, 98% BIOCHANIN A
• 5,7-Dihydrox -4'-methoxyisoflavone
• Biochanin A, (5,7-Dihydroxy-4’-methoxyisoflavone)
• Biochanin A，Genistein 4'-methyl ether，5,7-Dihydrox -4'-methoxyisoflavone
• 3-(4-Methoxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
• 4'-Methylgenistein
• NSC 123538
• Biochanin A (4-Methylgenistein)
• Biochanin A,5,7-Dihydroxy-4′-methoxyisoflavone, Genistein 4′-methyl ether
• 5,7-dihydroxy-3-(4-methoxyphenyl)-4h-1-benzopyran-4-on
• 5,7-dihydroxy-3-(4-methoxyphenyl)-4H-1-Benzopyran-4-one
• APIGENIN 4-METHYL ETHER
• 5,7-DIHYDROXY-4'-METHOXYISOFLAVONE
• 5,7-DIHYDROXY-4-METHOXYISOFLAVONE
• 5,7-dihydroxy-3-p-methoxyphenyl-4H-chromen-4-one
• 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-methoxyphenyl)-
• 5,7-Dihydroxy-4'-methoxyisoflavone Genistein 4'-methyl ether 5,7-Dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one
• 5,7-Dihydrox -4'-methoxyisoflavone 491-80-5
• 7-hydroxy-3-(4-methoxyphenyl)-4-oxo-1-benzopyran-5-olate
• Biochanin A >
• Genistein Methyl Ether
• Chickpea bud A
• 5,7-Dihydroxy-4'-methoxyisoflavone (Biochanin A)
• TIANFUCHEM--High purity 491-80-5 5,7-Dihydrox -4'-methoxyisoflavone
• Biochani,Olmelin
• 5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one
• BIOCHANIN A (AHP)
• BIOCHANIN
• 5,7-Dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one
• Bilchanin A
• OlMelin
• Pratensol
• BIOCHANIN A
• Genistein 4′-methyl ether
• Chickpea sproutin A
• Chickpea A
• 5,7- Dihydroxy - 4'- methoxy Isoflovone (or) Biochanin-A
• Chickpea sprout extract
• Biochanin A 98%min
• Chickpea dentin A
• 5,7-Dihydrox -4'-methoxyisoflavone
• 4-Methylgenistein|||Olmelin
• Biochanin A(P) (AHP Verified)
• Biochanin A-RM
• 491-80-5
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• chemical reagent
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• phytochemical
• reference standards from Chinese medicinal herbs (TCM).