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Riboflavin-5'-(natriumhydrogenphosphat)

Riboflavin 5'-Monophosphate Sodium Salt Struktur
130-40-5
CAS-Nr.
130-40-5
Bezeichnung:
Riboflavin-5'-(natriumhydrogenphosphat)
Englisch Name:
Riboflavin 5'-Monophosphate Sodium Salt
Synonyma:
RIBOFLAVIN SODIUM PHOSPHATE;FLAVIN MONONUCLEOTIDE;RIBOFLAVIN-5-PHOSPHATE;Ribo;RIBOFLAVIN 5'-PHOSPHATE SODIUM;Tenofovir Impurity 155;SODIUM RIBOFLAVIN PHOSPHATE;Vitamin B2 Sodium Phosphate;RIBOFLAVINE SODIUM PHOSPHATE;Riboflavin Phosphate Sodium Salt
CBNumber:
CB4472478
Summenformel:
C17H22N4NaO9P
Molgewicht:
480.35
MOL-Datei:
130-40-5.mol

Riboflavin-5'-(natriumhydrogenphosphat) Eigenschaften

Schmelzpunkt:
>300°C
alpha 
[α]D20 +38~+43° (c=1.5, dil. HCl) (Calculated on dehydrous basis)
FEMA 
2976 | QUININE HYDROCHLORIDE
Brechungsindex
41 ° (C=1.5, 5mol/L HCl)
storage temp. 
2-8°C
L?slichkeit
H2O: soluble50mg/mL, clear, orange
Aggregatzustand
powder
Farbe
Yellow to Dark Orange
Optische Aktivit?t
[α]20/D +37 to +42°, c = 1.5 in 5 M HCl(lit.)
Wasserl?slichkeit
almost transparency
Merck 
14,8201
BRN 
4106529
Stabilit?t:
Stable. Incompatible with strong oxidizing agents, reducing agents, bases, calcium, metallic salts. Protect from light, air and moisture.
LogP
-2.193 (est)
CAS Datenbank
130-40-5(CAS DataBase Reference)
EPA chemische Informationen
Riboflavin 5'-(dihydrogen phosphate), monosodium salt (130-40-5)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/38
S-S?tze: 22-24/25-37/39-26
WGK Germany  3
3-8-10
HS Code  29362300
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P271 Nur im Freien oder in gut belüfteten R?umen verwenden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

Riboflavin-5'-(natriumhydrogenphosphat) Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/38:Reizt die Augen und die Haut.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Chemische Eigenschaften

Riboflavin 5'-Monophosphate Sodium Salt is a yellow toorange-yellow, crystalline hygroscopic powder. It is odorless, and has a slightly bitter taste.
Riboflavin 5'-Monophosphate Sodium Salt
It is soluble in water, and practically insoluble in ethanol(95), in chloroform and in diethyl ether.
It is decomposed on exposure to light.

Verwenden

One of the bioactive forms of Riboflavin. Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, leafy vegetables. Richest natural source is yeast. Minute amounts present in all plant and animal cells. Vitamin (enzyme cofactor).

Application

Riboflavin 5'-Monophosphate Sodium Salt is a coenzyme that is tightly bound to enzymes catalyzing substrate oxidations and reductions, enable an enormous range of chemical transformations in biosynthetic pathways. Riboflavin 5'-Monophosphate Sodium Salt can be used as:
(1) A stable isotope internal standard for the interpretation of data in specific biological samples.
(2) An effective NAD+ reducing agent.
(3) To study progressive keratitis, corneal ectasia and irregular astigmatism.

Biologische Funktion

Riboflavin 5'-Phosphate Sodium is the phosphate sodium salt form of riboflavin, a water-soluble and essential micronutrient that is the principal growth-promoting factor in naturally occurring vitamin B complexes. Riboflavin phosphate sodium is converted to 2 coenzymes, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which are necessary for energy production by aiding in the metabolism of fats, carbohydrates and proteins and are required for red blood cell formation and respiration, antibody production and for regulating human growth and reproduction. Riboflavin phosphate sodium is essential for healthy skin, nails and hair growth.

Allgemeine Beschreibung

Riboflavin 5′-monophosphate is also known as flavin mononucleotide (FMN). FMN is a water-soluble micronutrient. It is enzymatically produced from riboflavin (RF). Riboflavin 5′-monophosphate is one of the constituent of enzyme cofactor flavin-adenine dinucleotide.

IC 50

Cryptosporidium hominis TS-DHFR: IC50 = 55 μM; Dihydrofolate reductase: IC50 = 325 μM (human); Thymidylate synthase: IC50 >500 μM (human); Dihydrofolate reductase: IC50 >500 μM (Toxoplasma gondii)

l?uterung methode

Purify FMN by paper chromatography using tert-butanol/water, cutting out the main spot and eluting it with water. It can also be purified by adsorption onto an apo-flavodoxin column, followed by elution and freeze drying. It crystallises from aqueous acidic solution. [Mayhew & Strating Eur J Biochem 59 539 1976, Beilstein 26 III/IV 2555.]

Riboflavin-5'-(natriumhydrogenphosphat) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Riboflavin-5'-(natriumhydrogenphosphat) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 586)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Oxsyns Biotech
+86-86-18382622232 +8618382622232
yilin.fan@oxsyns.com China 9 58
TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD
+86-576-88902229;+86-0576-88902229 +8613968687450
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15202951039
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Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578
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+8618882027439
sales2@runyanpharma.com China 302 58
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+86-15532196582 +86-15373005021
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Wuhan Quanjinci New Material Co.,Ltd.
+86-15271838296; +8615271838296
kyra@quanjinci.com China 1512 58

130-40-5(Riboflavin-5'-(natriumhydrogenphosphat))Verwandte Suche:


  • RIBOFLAVIN-5'-PHOSPHATE MONOSODIUM SALT
  • RIBOFLAVIN-5'-PHOSPHATE NA-SALT
  • RIBOFLAVIN-5-PHOSPHATE, SODIUM
  • RIBOFLAVIN 5'-PHOSPHATE SODIUM SALT
  • RIBOFLAVIN-5-PHOSPHATE SODIUM SALT
  • RIBOFLAVINI NATRII PHOSPHAS
  • VITAMIN B2-PHOSPHATE
  • VITAMIN B2 PHOSPHATE SODIUM
  • VITAMIN B2 PHOSPHATE SODIUM SALT
  • flavinmononucleotidesodium
  • RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT(P)
  • riboflavin5’-(dihydrogenphosphate),monosodiumsalt
  • flavin mononucleotide sodium*electrophoresis reag
  • riboflavin 5-(sodium hydrogen phosphate)
  • RIBOFLAVIN 5-PHOSPHATE SODIUM USP
  • Riboflavine 5'-monophosphate Sodium salt, Ph Eur
  • FLAVIN MONONUCLEOTIDE SODIUM*ELECTROPHOR ESIS REAGEN
  • Riboflavin-5'-MonophosphateSodium
  • Vitamin B2 5'-phosphate monosodium salt
  • RIBOFLAVIN5-PHOSPHATESODIUM,DIHYDRATE,ELECTROPHORESISGRADE
  • RIBOFLAVIN5-PHOSPHATESODIUM,DIHYDRATE,FCC
  • Alloxazine mononucleotide sodium salt
  • Benzo[g]pteridine, riboflavin 5'-(dihydrogen phosphate) deriv.
  • Coflavinase
  • Cytoflav
  • Flamotide
  • Hyryl
  • Riboflavin 5'-(dihydrogen phosphate), monosodium salt (9CI)
  • Riboflavin 5'-phosphate ester monosodium salt
  • Riboflavin 5′-monophosphate sodium salt
  • Riboflavin 5'-phosphate sodiuM, USP grade
  • 7,8-DiMethyl-10-ribitylisoalloxazine Phosphate SodiuM
  • Flavin Mononucleotide Lactoflavin Phosphate Sodium Salt Vitamin B2 Phosphate Sodium Salt
  • RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT(SH)
  • Riboflavin 5'-Monophosphate SodiuM Salt, 73.0 - 79.0% fluoriMetric
  • Riboflavine-5'
  • Riboflavin 5'-monophosphate sodium salt Riboflavini natrii phosphas Flavin Mononucleotide Lactoflavin Phosphate Sodium Salt Vitamin B2 Phosphate Sodium Salt
  • LACTOFLAVINE PHOSPHATE SODIUM SALT
  • LACTOFLAVIN-5'-PHOSPHATE SODIUM SALT
  • FLAVIN MONONUCLEOTIDE SODIUM SALT
  • FMN SODIUM SALT
  • ALLOXAZIN MONONUCLEOTIDE
  • RIBOFLAVINE 5'-MONOPHOSPHATE SODIUM SALT
  • RIBOFLAVINE 5-MONOPHOSPHATE SODIUM SALT
  • Riboflavin-5-phosphoric acid monosodium salt
  • Riboflavine 5'-(dihydrogen phosphate), monosodium salt (6CI, 8CI)
  • Riboflavine monosodium 5'-phosphate
  • Riboflavine, 5'-phosphate, sodium salt (7CI)
  • Sodium FMN
  • SODIUMRIBOFLAVIN5PHOSPHATE
  • RIBOFLAVINACIDSODIUMESTER
  • Riboflavin monophosphate monosodium salt
  • Flavin mononucleotide sodium salt dihydrate, FMN sodium salt dihydrate
  • Riboflavin 5'-phosphate sodium salt dihydrate, USP grade
  • Lactoflavin Phosphate Sodium Salt
  • Riboflavum -5 -dihydrophosphate monosodium salt
  • Ribofavin-5'-phosphate sodium salt dihydrate
  • Riboflavin 5′-monophosphate sodium salt,Riboflavin Sodium phosphate, Riboflavini natrii phosphas
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