2-Hexanon Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
FARBLOSE FLüSSIGKEIT MIT CHARAKTERISTISCHEM GERUCH.
CHEMISCHE GEFAHREN
Reagiert sehr heftig mit Oxidationsmitteln. Feuer- und Explosionsgefahr. Greift Kunststoffe an.
ARBEITSPLATZGRENZWERTE
TLV: 5 ppm (als TWA); 10 ppm (als STEL); Hautresorption; BEI vorhanden; (ACGIH 2005).
MAK: 5 ppm, 21 mg/m? Spitzenbegrenzung: überschreitungsfaktor II(8); Hautresorption; (DFG 2006).
AUFNAHMEWEGE
Aufnahme in den K?rper durch Inhalation und über die Haut.
INHALATIONSGEFAHREN
Beim Verdampfen bei 20°C kann schnell eine gesundheitssch?dliche Kontamination der Luft eintreten; viel schneller jedoch beim Versprühen oder Dispergieren.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION: Die Substanz reizt die Augen und die Atemwege. M?glich sind Auswirkungen auf das Nervensystem. Exposition weit oberhalb der Arbeitsplatzgrenzwerte kann zu Bewusstlosigkeit führen.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
Wiederholter oder andauernder Hautkontakt kann Dermatitis hervorrufen. M?glich sind Auswirkungen auf das Nervensystem.
LECKAGE
Ausgelaufene Flüssigkeit m?glichst in abdichtbaren Beh?ltern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen. Pers?nliche Schutzausrüstung: Umgebungsluftunabh?ngiges Atemschutzger?t.
R-S?tze Betriebsanweisung:
R10:Entzündlich.
R48/23:Giftig: Gefahr ernster Gesundheitssch?den bei l?ngerer Exposition durch Einatmen.
R62:Kann m?glicherweise die Fortpflanzungsf?higkeit beeintr?chtigen.
R67:D?mpfe k?nnen Schl?frigkeit und Benommenheit verursachen.
R39/23/24/25:Giftig: ernste Gefahr irreversiblen Schadens durch Einatmen, Berührung mit der Haut und durch Verschlucken.
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
R11:Leichtentzündlich.
S-S?tze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S16:Von Zündquellen fernhalten - Nicht rauchen.
S7:Beh?lter dicht geschlossen halten.
Beschreibung
2-Hexanone has been used as a solvent for both cellulose- and
resin-based coating systems. In the early 1970s, a number of
workers in the print department of a coated fabrics plant
developed severe peripheral neuropathy from an unknown
cause. In search of an etiological agent, and in the absence of
other neurotoxicants, 2-hexanone was implicated as it was
recently substituted for methyl isobutyl ketone in the
manufacturing process. Similar observations in workers
exposed to 2-hexanone may have resulted in the decline in
production and use in the United States.
Chemische Eigenschaften
2-Hexanone is a colorless to pale yellow liquid with a sharp odor. It dissolves very easily in
water and is miscible in ethanol, methanol, and benzene. 2-Hexanone evaporates easily into
the air as a vapor. It is stable, flammable, and incompatible with oxidizing agents, strong bases,
and reducing agents. 2-Hexanone is a waste product of wood pulping, coal gasifi cation, and
oil shale operations. Formerly, 2-hexanone was in use as a paint and paint thinner with other
chemical substances, and to dissolve oils and waxes.and is used as a solvent and organic syn-
thesis intermediates. However, the industrial uses of 2-hexanone is now very much restricted.
Physikalische Eigenschaften
Clear, colorless to pale yellow, flammable liquid with an odor resembling acetone and 2-butanone.
Nagata and Takeuchi (1990) reported an odor threshold concentration of 24 ppb
v. Amoore and
Hautala (1983) reported odor threshold concentrations of 250 μg/L and 76 ppb
v in water and air,
respectively.
Verwenden
2-Hexanone is used in various organic chemical syntheses. It is used in the synthesis of (+/-)-monomorine. It is also used in the preparation of alcohols by transfer hydrogenation of ketones.
Vorbereitung Methode
MnBK can be produced by a reaction between acetic acid and ethylene under pressure MnBK can be produced by a reaction between acetic acid and ethylene under pressure.
Allgemeine Beschreibung
A clear colorless liquid. Flash point 95°F. Less dense than water. Vapors heavier than air.
Air & Water Reaktionen
Highly flammable. Slightly soluble in water.
Reaktivit?t anzeigen
2-Hexanone is incompatible with oxidizing agents. 2-Hexanone may also react with strong bases and reducing agents.
Hazard
Flammable, moderate fire risk, explosive limits 1.2–8% in air. Irritant to eyes and
mucous membranes, narcotic in high concentration,
absorbed by skin. Causes peripheral neuropathy and
testicular damage.
Health Hazard
Inhalation of high concentrations of vapor may result in narcosis; peripheral neuropathy may develop. Ingestion of large amounts may cause some systemic injury. Contact with eyes causes mild to moderate irritation. Liquid irritates skin; prolonged or repeated contact may cause defatting of the skin with resultant dermatitis.
Brandgefahr
2-Hexanone is flammable.
m?gliche Exposition
The material is used as a solvent
Environmental Fate
Biological. Using the BOD technique to measure biodegradation, the mean 5-d BOD value (mM
BOD/mM 2-hexanone) and ThOD were 5.22 and 61.4%, respectively (Vaishnav et al., 1987).
Photolytic. A second-order photooxidation rate constant of 8.97 x 10
-12 cm
3/molecule?sec for the
reaction of 2-hexanone and OH radicals in the atmosphere at 299 K was reported by Atkinson
(1985).
Chemical/Physical. 2-Hexanone will not hydrolyze because it has no hydrolyzable functional
group (Kollig, 1995).
Lager
2-Hexanone should be kept stored in a tightly closed container, in a cool, dry place, away
from sources of ignition.
Versand/Shipping
UN1224 Ketones, liquid, n.o.s., Hazard Class: 3;
Labels: 3-Flammable liquid, Technical Name Required
Waste disposal
Dissolve or mix the
material with a combustible solvent and burn in a chemical
incinerator equipped with an afterburner and scrubber.
All federal, state, and local environmental regulations
must be observed.
Vorsichtsma?nahmen
Occupational workers should be careful when using and handling 2-hexanone. Workers
should wash thoroughly after handling the chemical substance. Workers should avoid contact of 2-hexanone with the eyes, skin, and clothing and also avoid contact with heat,
sparks, and flame.
2-Hexanon Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
