6384-92-5
中文名稱
N-甲基-D-天冬氨酸
英文名稱
N-Methyl-D-aspartic acid
CAS
6384-92-5
EINECS 編號
227-012-0
分子式
C5H9NO4
MDL 編號
MFCD06795789
分子量
147.13
MOL 文件
6384-92-5.mol
更新日期
2024/12/20 09:15:53
6384-92-5 結(jié)構(gòu)式
基本信息
中文別名
(R)-2-(甲基氨基)丁二酸N-甲基-D-天冬氨酸
N-甲基-D-天門冬胺基乙酸
N-甲基-D-天(門)冬氨酸
英文別名
H-D-MEASP-OHH-D-MEASP-OH HCL
N-ALPHA-METHYL-D-ASPARTIC ACID
N-ALPHA-METHYL-D-ASPARTIC ACID HYDROCHLORIDE
NMDA
N-ME-D-ASPARTIC ACID
N-ME-D-ASP-OH
N-ME-D-ASP-OH HCL
N-METHYL-D-ASPARAGINIC ACID
N-METHYL-D-ASPARTIC ACID
N-METHYL-D-ASPARTIC ACID HYDROCHLORIDE
[R]-2-[METHYLAMINO]SUCCINIC ACID
n-methylaspartate
n-methyl-d-aspartate
n-methyl-d-asparticaci
N-Methyl D-artic acid.
(2R)-2-methylaminobutanedioic acid
(R)-2-(Methylamino)succinic acid, NMDA
(R)-2-(Methylamino)butanedioic acid
N-Methyl-D-Asp-OH
所屬類別
生物化工：天冬氨酸類衍生物物理化學(xué)性質(zhì)
熔點(diǎn)187-192 °C
熔點(diǎn)187-192 °C
比旋光度-28 º (c=1, HCl 6N)
沸點(diǎn)267.21°C (rough estimate)
密度1.4285 (rough estimate)
折射率-15 ° (C=2, H2O)
儲存條件Sealed in dry,Room Temperature
儲存條件Store at RT.
溶解度可溶于酸性水溶液（少許）、DMSO（少許）、水（少許）
酸度系數(shù)(pKa)2.21±0.23(Predicted)
形態(tài)solid
顏色white
水溶解性微溶
敏感性吸濕性
Merck14,6662
Merck6662
BRN1724431
LogP1.390 (est)
CAS 數(shù)據(jù)庫6384-92-5(CAS DataBase Reference)
安全數(shù)據(jù)
警示詞危險(xiǎn)
危險(xiǎn)性描述H319-H400-H372
安全說明22-24/25
安全說明S22-S24/25
WGK Germany3
WGK Germany3
RTECS號CI9457000
F10
海關(guān)編碼29225090
知名試劑公司產(chǎn)品信息
Acros Organics
N-甲基-D-天門冬氨酸N-Methyl-D-aspartic acid, 98%(6384-92-5)
Sigma Aldrich
6384-92-5(sigmaaldrich)N-甲基-D-天冬氨酸價(jià)格(試劑級)
| 報(bào)價(jià)日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價(jià)格 |
| 2024/11/08 | 32919 | N-甲基-D-天冬氨酸 1GR N-Methyl-D-aspartic acid, 98%, Thermo Scientific Chemicals | 6384-92-5 | 50mg | 1071元 |
| 2024/11/08 | 32919 | N-甲基-D-天冬氨酸 1GR N-Methyl-D-aspartic acid, 98%, Thermo Scientific Chemicals | 6384-92-5 | 250mg | 5081元 |
| 2024/11/08 | M1360 | N-甲基-D-天冬氨酸 N-Methyl-D-aspartic Acid | 6384-92-5 | 100MG | 90元 |
常見問題列表
生物活性
NMDA (N-Methyl-D-aspartic acid)是一種特異性NMDA受體激動劑，通常作為受體，模擬神經(jīng)遞質(zhì)谷氨酸的活性。Phase 4。靶點(diǎn)
| Target | Value |
| NMDA receptor |
體外研究
NMDA是興奮性氨基酸神經(jīng)遞質(zhì)，只與NMDA受體結(jié)合，而不會影響其他谷氨酸受體（如AMPA和Kainate)。NMDA特異性與NMDA受體的NR2亞基結(jié)合，刺激非特異性陽離子通道的打開，使Ca
體內(nèi)研究
NMDA (0.2 nM) shows significant effects on MF, IF, IL, and EL, respectively, decreasing the mount and intromission frequencies, and shortening the intromission and ejaculation latencies. NMDA and AP-5 significantly, respectively, facilitates and inhibits the ejaculatory behavior during the copulation testing 30 min. Bilateral microinjection of NMDA into PVN significantly increases the baseline LSNA, the peaking increment of LSNA occurred within 5 min from the time of NMDA microinjected into PVN.