54-92-2
中文名稱
異丙煙肼
英文名稱
iproniazid
CAS
54-92-2
分子式
C9H13N3O
分子量
179.222
MOL 文件
54-92-2.mol
更新日期
2024/12/18 13:15:42
54-92-2 結(jié)構(gòu)式
基本信息
中文別名
異丙煙肼異煙酰異丙肼
N'-異丙基異煙肼
英文別名
IPRAZIDiproniazid
N'-Isopropylpyridine-4-Carbohydrazide
N'-propan-2-ylpyridine-4-carbohydrazide
物理化學(xué)性質(zhì)
熔點(diǎn)112.5-113.5°
沸點(diǎn)311.75°C (rough estimate)
密度1.1305 (rough estimate)
折射率1.5100 (estimate)
儲(chǔ)存條件Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
溶解度可溶于DMSO（少許）、甲醇（少許）
酸度系數(shù)(pKa)11.28±0.23(Predicted)
形態(tài)固體
顏色淺米色
CAS 數(shù)據(jù)庫54-92-2
安全數(shù)據(jù)
警示詞警告
危險(xiǎn)性描述H302
海關(guān)編碼2933399990
毒性An isopropyl derivative of isoniazid that was
found to have mood-elevating effects in tuberculosis patients.
It was later found to be a monoamine oxidase (MAO) inhibitor
and, although not currently approved for clinical use as an
antidepressant due to its propensity to cause liver damage it
led to the development of other MAO inhibitors currently in
use. In addition to hepatotoxic effects, iproniazid is a hypotensive
agent and can cause potentially hazardous reactions with
other drugs and amine-rich foods.