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1989-52-2

中文名稱 膽甾烯基豆蔻酸酯
英文名稱 Cholesteryl myristate
CAS 1989-52-2
EINECS 編號 217-867-8
分子式 C41H72O2
MDL 編號 MFCD00014256
分子量 597.01
MOL 文件 1989-52-2.mol
更新日期 2023/03/20 15:41:19
1989-52-2 結(jié)構(gòu)式 1989-52-2 結(jié)構(gòu)式

基本信息

中文別名
膽甾醇豆蔻酸酯
膽甾烯基豆蔻酸酯
肉豆蔻酸膽固醇
膽固醇肉豆蔻酸酯,液晶
肉豆蔻酸膽固醇酯
英文別名
3BETA-HYDROXY-5-CHOLESTENE 3-TETRADECANOATE
[(3s,8s,9s,10r,13r,14s,17r)-10,13-dimethyl-17-[(2r)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3-yl] tetradecanoate
5-CHOLESTEN-3BETA-OL 3-TETRADECANOATE
5-CHOLESTEN-3-BETA-OL MYRISTATE
Cholest-5-en-3beta-yl myristate
CHOLESTEROL MYRISTATE
CHOLESTERYL MYRISTATE
CHOLESTERYL TETRADECANOATE
CHOLESTERYL TETRADODEDECANOATE
MYRISTIC ACID CHOLESTEROL ESTER
(3β)-cholest-5-en-3-yltetradecanoate
3β-tetradecanoyloxycholest-5-ene
Cholest-5-en-3-ol (3beta)-, tetradecanoate
Cholest-5-en-3-yl myristate
Cholestryl myristate
CM
tetradecanoate
CHOLESTERYL MYRISTATE (TETRADECANOATE)
CHOLESTERYL MYRISTATE, LIQUID CRYSTAL 99%
Cholesteryl myristate, liquid crystal, 97%
所屬類別
有機(jī)原料:羧酸類化合物及衍生物

物理化學(xué)性質(zhì)

熔點(diǎn)84 °C
沸點(diǎn)589.77°C (rough estimate)
密度0.9309 (rough estimate)
折射率1.5250 (estimate)
儲存條件−20°C
溶解度氯仿(微溶)、己烷(微溶)
形態(tài)結(jié)晶固體
顏色White to off-white
LogP16.656 (est)
CAS 數(shù)據(jù)庫1989-52-2(CAS DataBase Reference)
NIST化學(xué)物質(zhì)信息Cholesteryl myristate(1989-52-2)

安全數(shù)據(jù)

危險(xiǎn)性符號(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險(xiǎn)性描述H302
危險(xiǎn)品標(biāo)志Xi
危險(xiǎn)類別碼36/37/38
安全說明26-36
WGK Germany3

知名試劑公司產(chǎn)品信息

常見問題列表

生物活性
Cholesterol myristate 是中藥中天然類固醇。Cholesterol myristate 與多種離子通道結(jié)合,例如 nAChR,GABAA receptor 和內(nèi)向整流鉀離子通道 (potassium ion channel)。
靶點(diǎn)

Human Endogenous Metabolite

體外研究

Mesenchymal stem cells (MSCs) transfected by the Id1 promoter reporter construct, cholesterol myristate increases the activity of Id1 promoter. Cholesterol myristate inhibits the apoptosis of MSCs induced by serum-free. Cholesterol myristate increases the expression of Id1 and its target gene bcl-x/l in MSCs treated with serum-free. Moreover, noggin, a BMP antagonist, reduces the anti-apoptotic effects of cholesterol myristate. Cholesterol myristate inhibits the apoptosis of PC12 cells induced in serum-free condition. Cholesterol myristate significantly increases the expression of BMP4, BMPRIA, p-Smad1/5/8, Id1 and its antiapoptotic target gene Bcl-xL in PC12 cells treated in serum-free condition.

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