129-43-1
中文名稱
1-羥基蒽醌
英文名稱
1-Hydroxy anthraquinone
CAS
129-43-1
EINECS 編號
204-946-7
分子式
C14H8O3
MDL 編號
MFCD00058946
分子量
224.21
MOL 文件
129-43-1.mol
更新日期
2024/12/25 20:56:37
129-43-1 結(jié)構(gòu)式
基本信息
中文別名
1-羥基蒽醌1-羥基-9,10-蒽二酮
α-羥基蒽醌
1-羥蒽醌
英文別名
1-hydroxy-9,10-anthracenedione1-HYDROXYANTHRAQUINONE
4-HYDROXYANTHRAQUINONE
10-Anthracenedione,1-hydroxy-9
1-hydroxy-10-anthracenedione
1-Hydroxy-9,10-anthraquinone
1-Hydroxyanthra-9,10-quinone
1-Hydroxyanthrachinon
1-hydroxy-anthraquinon
alpha-Hydroxyanthraquinone
Anthraquinone, 1-hydroxy-
I-0syanthrachinon
1-hydroxyanthracene-9,10-dione
NISTC129431
erythroxyanthraquinone
所屬類別
有機原料：醌類化合物物理化學(xué)性質(zhì)
外觀橘黃色粉末。
熔點194°C
沸點325.61°C (rough estimate)
密度1.2337 (rough estimate)
折射率1.5400 (estimate)
儲存條件Inert atmosphere,Room Temperature
溶解度Chloroform: 30 mg/ml
酸度系數(shù)(pKa)7.15±0.20(Predicted)
形態(tài)粉末晶體
顏色淺黃色至棕色
CAS 數(shù)據(jù)庫129-43-1(CAS DataBase Reference)
(IARC)致癌物分類2B (Vol. 82) 2002
NIST化學(xué)物質(zhì)信息9,10-Anthracenedione, 1-hydroxy-(129-43-1)
EPA化學(xué)物質(zhì)信息9,10-Anthracenedione, 1-hydroxy- (129-43-1)
安全數(shù)據(jù)
警示詞警告
危險性描述H320-H351
危險品標志Xn
危險類別碼R36/37/38
安全說明S26-S36/37/39
RTECS號CB7178000
包裝等級III
Class6.1
UN編號2811
海關(guān)編碼2914.69.9000
毒害物質(zhì)數(shù)據(jù)129-43-1(Hazardous Substances Data)
知名試劑公司產(chǎn)品信息
Sigma Aldrich
129-43-1(sigmaaldrich)TCI Shanghai
1-羥基蒽醌1-Hydroxyanthraquinone,>95.0%(T)(129-43-1)
1-羥基蒽醌價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/11/08 | H0354 | 1-羥基蒽醌 1-Hydroxyanthraquinone | 129-43-1 | 5g | 170元 |
| 2024/11/08 | HY-W000838 | 1-羥基蒽醌 1-Hydroxyanthraquinone | 129-43-1 | 500mg | 500元 |
| 2024/11/08 | HY-W000838 | 1-羥基蒽醌 1-Hydroxyanthraquinone | 129-43-1 | 10mM * 1mLin DMSO | 550元 |
常見問題列表
生物活性
1-Hydroxyanthraquinone 是具有口服活性的天然產(chǎn)物，可來源于一些植物如 Tabebuia avellanedae，具有致癌作用。體內(nèi)研究
1-Hydroxyanthraquinone (HA) generates strong DNA repair response and is carcinogenic in rats.
| Animal Model: | Thirty rats. |
| Dosage: | 1% HA in diet. |
| Administration: | Diet. |
| Result: |
Associated with decreased weight gain which was particularly marked towards the termination of experiment.
One of the 30 rats in group 1 (experimental group) died of pneumonia 243 days after the start of experiment. A second rat died in an unnourished state at day 280, demonstrating a large tumor in the colon. Seven animals of the group died spontaneously or were sacrificed upon becoming moribund between 335 and 462 days. A total of 21 rats of group 1 survived until the end of experiment (mean value of total intake of HA/rat was 76.8 g). |