Identification | More | [Name]
Cefteram pivoxil | [CAS]
82547-58-8 | [Synonyms]
CEFTERAM 2,2-Dimethylpropanoyloxymethyl (6R,7R)-7-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetylamino]-3-(5-methyl-2H-tetrazol-2-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Cefteram pivoxil (+)-(6R,7R)-7-[(Z)-2-(2-Amincr4-thiazolyl)-2-(methoxyimino)acetami-do]-3-[(5-methyl-2H-tetrazol-2-y1)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Ceftetrame Ro-19-5247 T-2525 Tomimn (6R,6β)-7α-[[(2-Amino-4-thiazolyl)[(Z)-methoxyimino]acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid [6R,7R,(+)]-7α-[[2-(2-Aminothiazol-4-yl)-2-[(Z)-methoxyimino]acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Antibiotic Ro-19-5247 | [Molecular Formula]
C16H17N9O5S2 | [MDL Number]
MFCD00864913 | [Molecular Weight]
479.49 | [MOL File]
82547-58-8.mol |
Chemical Properties | Back Directory | [Melting point ]
>175°C (dec.) | [density ]
1.95±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
DMF (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
2.62±0.50(Predicted) | [color ]
White to Pale Yellow | [InChIKey]
XSPUSVIQHBDITA-RKYNPMAHSA-N | [SMILES]
N12[C@@]([H])([C@H](NC(/C(/C3=CSC(N)=N3)=N\OC)=O)C1=O)SCC(CN1N=NC(C)=N1)=C2C(O)=O | [CAS DataBase Reference]
82547-58-8(CAS DataBase Reference) |
Hazard Information | Back Directory | [Description]
Cefteram pivoxil is an orally-active cephalosponn antibiotic with a broad spectrum of
activity. It is reportedly effective against Cirrobacrer, indole-positive Proreus and
Enrerobacrer species resistant to cefaclor, cephalexin and amoxicillin. Cefteram pivoxil is
indicated primarily for urinary tract infections. | [Chemical Properties]
Pale Yellow Solid | [Originator]
Toyama (Japan) | [Uses]
Orally active cephalosporin antibiotic, antibacterial. | [Definition]
ChEBI: Cefteram is a cephalosporin compound having (5-methyl-2H-tetrazol-2-yl)methyl and [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side-groups; a third-generation cephalosporin antibiotic. | [Brand name]
Tomiron | [Antimicrobial activity]
A semisynthetic cephalosporin formulated for oral administration
as the prodrug ester, cefteram pivoxil. Activity is similar
to that of cefixime, but with slightly better activity against
staphylococci and some Gram-negative rods.
Available in Japan. |
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