| Identification | More | [Name]
DL-Serine | [CAS]
302-84-1 | [Synonyms]
(+/-)-2-AMINO-3-HYDROXYPROPIONIC ACID
2-AMINO-3-HYDROXY-PROPIONIC ACID
DL-2-AMINO-3-HYDROXYPROPANOIC ACID
DL-2-AMINO-3-HYDROXYPROPIONIC ACID
DL-BETA-HYDROXYALANINE
DL-SER
DL-SERINE
H-DL-SER-OH
SERINE
(R,S)-2-Amino-3-hydroxy-propionicacid
L-HOCH2CH(NH2)COOH
Serine, dl-
DL-SERINE CELL CULTURE TESTED
DL-SERINE 99+%
Dl-SerinePuriss99+%
Dl-SerinePuriss
DL-SERINE FOR BIOCHEMISTRY
(n)-2-amino-3-hydroxypropionic acid
DL-SERINE,FCC
DL-Serin | [EINECS(EC#)]
206-130-6 | [Molecular Formula]
C3H7NO3 | [MDL Number]
MFCD00064223 | [Molecular Weight]
105.09 | [MOL File]
302-84-1.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystalline powder | [Melting point ]
240 °C (dec.) (lit.) | [Boiling point ]
197.09°C (rough estimate) | [density ]
1.53
| [refractive index ]
1.4368 (estimate) | [storage temp. ]
Store at RT. | [solubility ]
H2O: soluble | [form ]
Crystalline Powder | [pka]
2.19(at 25℃) | [color ]
White | [Odor]
Odorless | [Water Solubility ]
50.23 g/L (25 ºC) | [Merck ]
14,8460 | [BRN ]
1721402 | [LogP]
-3.460 | [Uses]
serine is a hydrophilic amino acid. Serine helps retain the skin’s moisture balance. | [CAS DataBase Reference]
302-84-1(CAS DataBase Reference) | [NIST Chemistry Reference]
DL-Serine(302-84-1) | [EPA Substance Registry System]
302-84-1(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [RTECS ]
VT8100000 | [TSCA ]
Yes | [HS Code ]
29225000 | [Safety Profile]
When heated to decomposition emits toxic fumes of NOx. |
| Hazard Information | Back Directory | [Description]
DL-Serine is a kind of neutral aliphatic amino acids containing hydroxyl groups with polarity but being uncharged, and belongs to nonessential amino acids for human body. It has a high content in sericin silk protein and fibroin protein. It can be formed from the methyl transfer reaction of glycine. It can also be converted to pyruvate or hydroxy pyruvate through deamination. It is also an important raw material for in vivo synthesis of choline and cysteine. | [Chemical Properties]
DL-Serine is a kind of colorless monoclinic columnar or lamellae crystal. It is soluble in water (at 20℃, the water solubility is 380g/L), insoluble in ether and ethanol; Decomposition point: 246℃. | [Application]
Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2.
DL-Serine is used in the synthesis of novel tryptoline derivatives as IDO (indoleamine 2,3-Deoxygenase) inhibitors, for potential use in Alzheimer?s treatment. | [Definition]
ChEBI: An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group. | [Preparation]
DL-serine is obtained by complexing glycine under the catalysis of copper ions and then combining with formaldehyde under alkaline conditions, followed by acidification, ion exchange, and crystallization in ethanol.? | [Synthesis Reference(s)]
Canadian Journal of Chemistry, 33, p. 1119, 1955 DOI: 10.1139/v55-131
The Journal of Organic Chemistry, 35, p. 1505, 1970 DOI: 10.1021/jo00830a054 | [Biochem/physiol Actions]
NMDA agonist acting at the glycine site; precursor of glycine by serine hydroxymethyltransferase | [in vitro]
DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV).
Subcutaneous injection of DL-serine increases the number and size of renal tubular cell tumors in male W rats treated with 500 or 1,000 ppm N-ethyl-N-hydroxyethylnitrosamine. |
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