Identification | More | [Name]
3-Aminopyridine | [CAS]
462-08-8 | [Synonyms]
3-AMINOPYRIDINE 3APY 3-pyridinamine 3-PYRIDYLAMINE AKOS 90977 AMINOPYRIDINE, 3- BETA-AMINOPYRIDINE B-PYRIDYLAMINE m-Aminopyridine PYRIDIN-3-YLAMINE TIMTEC-BB SBB004395 3-amino-pyridin Amino-3 pyridine amino-3pyridine Pyridine, 3-amino- 3-AMINOPYRIDINE PESTANAL 3-AMINOPYRIDINE 99+% AMINOPYRIDINE, 2-(PRIMARY STANDARD) 3-AMINO PYRIDINE FOR SYNTHESIS pyridin-3-amine | [EINECS(EC#)]
207-322-2 | [Molecular Formula]
C5H6N2 | [MDL Number]
MFCD00006400 | [Molecular Weight]
94.11 | [MOL File]
462-08-8.mol |
Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
60-63 °C(lit.)
| [Boiling point ]
248 °C(lit.)
| [density ]
1.0308 (estimate) | [refractive index ]
1.5560 (estimate) | [Fp ]
124 °C
| [storage temp. ]
Poison room | [solubility ]
>1000g/l | [form ]
Liquid | [pka]
6.04(at 25℃) | [color ]
Clear colorless to yellow | [PH]
10 (100g/l, H2O, 20℃) | [Water Solubility ]
It is soluble in water as well as soluble in alcohol, benzene. | [Sensitive ]
Air Sensitive & Hygroscopic | [Detection Methods]
GC,NMR | [Merck ]
14,473 | [BRN ]
105692 | [InChIKey]
CUYKNJBYIJFRCU-UHFFFAOYSA-N | [LogP]
0.110 | [CAS DataBase Reference]
462-08-8(CAS DataBase Reference) | [NIST Chemistry Reference]
3-Pyridinamine(462-08-8) | [EPA Substance Registry System]
462-08-8(EPA Substance) |
Safety Data | Back Directory | [Hazard Codes ]
T,Xi | [Risk Statements ]
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed . R33:Danger of cumulative effects. R36/37/38:Irritating to eyes, respiratory system and skin . R25:Toxic if swallowed. | [Safety Statements ]
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . S37/39:Wear suitable gloves and eye/face protection . S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
UN 2671 6.1/PG 2
| [WGK Germany ]
3
| [RTECS ]
US1650000
| [F ]
3-8-9-23 | [Hazard Note ]
Toxic/Irritant | [TSCA ]
T | [HazardClass ]
6.1 | [PackingGroup ]
II | [HS Code ]
29333999 | [Safety Profile]
Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NOx,. | [Toxicity]
LD50 ipr-mus: 28 mg/kg JMCMAR 8,296,65 |
Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powder | [Uses]
3-Aminopyridine is a monosubstituted pyridine that shows convulsive effects on cortical Neurons. 3-Aminopyridine is used in the synthesis of of organic ligand 3-Pyridylnicotinamide. 3-Aminopyridine al
ong with other aminopyridines have been shown to reversibly block voltage-dependent potassium channels, | [Uses]
manufacture of pharmaceuticals and dyes. | [Synthesis Reference(s)]
Tetrahedron Letters, 39, p. 1313, 1998 DOI: 10.1016/S0040-4039(97)10877-2 The Journal of Organic Chemistry, 57, p. 5254, 1992 DOI: 10.1021/jo00045a047 | [Purification Methods]
It crystallises from *benzene, CHCl3/pet ether (b 60-70o), or *benzene/pet ether (4:1). [Beilstein 22/9 V 3.] |
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