![144391-74-2](/CAS/20150408/GIF/CB52665486.gif)
SalMeterol iMpurity synthesis
- Product Name:SalMeterol iMpurity
- CAS Number:144391-74-2
- Molecular formula:C25H37NO4
- Molecular Weight:415.5656
![Methanone, phenyl(2-phenyl-1-pyrrolidinyl)-](/CAS/20210305/GIF/98528-33-7.gif)
98528-33-7
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![SalMeterol iMpurity](/CAS/20150408/GIF/CB52665486.gif)
144391-74-2
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Yield:144391-74-2 84 %
Reaction Conditions:
Stage #1: phenyl(2-phenylpyrrolidin-1-yl)methanonewith tris(pentafluorophenyl)borate;phenylsilane at 120;Sealed tube;
Stage #2: with hydrogenchloride in diethyl ether at 20;regioselective reaction;
References:
Peng, Yi;Oestreich, Martin [Chemistry - A European Journal,2023,vol. 29,# 13,art. no. E202203721] Location in patent:supporting information
![Pyrrolidine, 2-phenyl-1-(phenylmethyl)-](/CAS/20200515/GIF/1025-56-5.gif)
1025-56-5
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![SalMeterol iMpurity](/CAS/20150408/GIF/CB52665486.gif)
144391-74-2
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![5-PHENYL-2-PYROLLIDINONE](/CAS/GIF/22050-10-8.gif)
22050-10-8
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![SalMeterol iMpurity](/CAS/20150408/GIF/CB52665486.gif)
144391-74-2
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![2-Phenylpyrrolidine](/CAS/GIF/1006-64-0.gif)
1006-64-0
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$16.00/500mg
![Benzyl bromide](/CAS/GIF/100-39-0.gif)
100-39-0
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$10.00/10g
![SalMeterol iMpurity](/CAS/20150408/GIF/CB52665486.gif)
144391-74-2
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![2-Phenylpyrrolidine](/CAS/GIF/1006-64-0.gif)
1006-64-0
183 suppliers
$16.00/500mg
![Benzoyl chloride](/CAS/GIF/98-88-4.gif)
98-88-4
583 suppliers
$10.00/5g
![SalMeterol iMpurity](/CAS/20150408/GIF/CB52665486.gif)
144391-74-2
23 suppliers
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