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ChemicalBook CAS DataBase List Ethyl Succinyl Chloride
14794-31-1

Ethyl Succinyl Chloride synthesis

4synthesis methods
-

Yield:14794-31-1 95%

Reaction Conditions:

with thionyl chloride in dichloromethane;N,N-dimethyl-formamide at 38; for 5 h;Inert atmosphere;

Steps:

1
Compound II (116.8g, 0 . 8mol), dichloromethane (300 ml) and thionyl chloride (104g, 0.88mol) are added to a reaction flask, N 2 adding N under protection, N-dimethyl formamide (0.8g), 38 °C heating reflux stirring for 5 hours, the reaction is complete, to obtain compound III concentration of methylene chloride (124g, yield: 95%).

References:

Chengdu Baiyuzhi Pharmaceutical co., LTD;WEI, NONG NONG;CHEN, MAO PING;YANG, YING LANG;XIONG, WU CN104326922, 2016, B Location in patent:Paragraph 0038; 0040

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