3,5-Dimethoxytoluene synthesis
- Product Name:3,5-Dimethoxytoluene
- CAS Number:4179-19-5
- Molecular formula:C9H12O2
- Molecular Weight:152.19
504-15-4
393 suppliers
$7.00/100mg
4179-19-5
160 suppliers
$6.00/1g
Yield:4179-19-5 82%
Reaction Conditions:
with potassium carbonate;dimethyl sulfate in acetonitrile
Steps:
44 Example 44
Example 44 (Reference Example) 3,5-dimethoxy toluene Commercially available orcinol (5.77 g) was dissolved in acetonitrile (200 ml), dimethyl sulfate (8.47 ml) and potassium carbonate (12.3 g) were added, and the admixture was refluxed for 2.5 hours. The reaction mixture was poured into ice water and partitioned with chloroform, and the chloroform layer was dried with anhydrous magnesium sulfate. The solvent was removed by reduced-pressure distillation, and the resulting residue was purified by column chromatography on silica gel eluding with hexane/ethyl acetate (5/1) to obtain 5.04 g of the title compound (yield: 82%). 1 H-NMR (CDCl3, 500 MHz): δ 2.30 (s, 3H), 3.76 (s, 6H), 6.30 (s, 1H), 6.37 (s, 2H)
References:
Kirin Beer Kabushiki Kaisha US6143764, 2000, A
7311-34-4
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$10.00/1g
4179-19-5
160 suppliers
$6.00/1g
504-15-4
393 suppliers
$7.00/100mg
77-78-1
303 suppliers
$19.69/1ml
4179-19-5
160 suppliers
$6.00/1g
877-88-3
227 suppliers
$5.00/250mg
4179-19-5
160 suppliers
$6.00/1g
7051-16-3
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$10.00/1g
75-16-1
269 suppliers
$12.00/10ml
4179-19-5
160 suppliers
$6.00/1g