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ChemicalBook >> CAS DataBase List >> Tandutinib

Tandutinib

Tandutinib price.
  • $45 - $2500
  • Product name: Tandutinib
  • CAS: 387867-13-2
  • MF: C31H42N6O4
  • MW: 562.7
  • EINECS:
  • MDL Number:MFCD09954147
  • Synonyms:Tandutinib;1-Piperazinecarboxamide, 4-(6-methoxy-7-(3-(1-piperidinyl)propoxy)-4-quinazolinyl)-N-(4-(1-methylethoxy)phenyl)-;4-(6-Methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl)piperazine-1-carboxylic acid (4-isopropoxyphenyl)amide;Unii-E1io3icj9a;Tandutinib(CT 53518);Tandutinib (MLN518);CT53518; MLN518;Tandutinib(TINIBS)
31 prices
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Brand
  • Adipogen Life Sciences
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 2.5mg
  • 5mg
  • 10mg
  • 10mM(in 1mL DMSO)
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1088-M010
  • Product descriptionTandutinib ≥95%
  • Packaging10mg
  • Price$81
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1526
  • Product descriptionTandutinib(MLN518)
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7853
  • Product descriptionTandutinib(MLN518)HCl
  • Packaging200mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60446
  • Product descriptionTandutinib(MLN518)
  • Packaging20mg
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2203
  • Product descriptionTandutinib
  • Packaging25mg
  • Price$129
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2203
  • Product descriptionTandutinib
  • Packaging100mg
  • Price$269
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2203
  • Product descriptionTandutinib
  • Packaging1g
  • Price$890
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT28001
  • Product descriptionTandutinib
  • Packaging10mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT28001
  • Product descriptionTandutinib
  • Packaging50mg
  • Price$158
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number12098
  • Product descriptionTandutinib ≥95%
  • Packaging25mg
  • Price$56
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number12098
  • Product descriptionTandutinib ≥95%
  • Packaging50mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number12098
  • Product descriptionTandutinib ≥95%
  • Packaging100mg
  • Price$140
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number12098
  • Product descriptionTandutinib ≥95%
  • Packaging250mg
  • Price$311
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0128
  • Product descriptionTandutinib 99.48%
  • Packaging50mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0128
  • Product descriptionTandutinib 99.48%
  • Packaging100mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0128
  • Product descriptionTandutinib 99.48%
  • Packaging200mg
  • Price$168
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1088-M010 Tandutinib ≥95% 10mg $81 2021-12-16 Buy
ApexBio Technology B1526 Tandutinib(MLN518) 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B7853 Tandutinib(MLN518)HCl 200mg $140 2021-12-16 Buy
Arctom CFN60446 Tandutinib(MLN518) 20mg $98 2021-12-16 Buy
AvaChem 2203 Tandutinib 25mg $129 2021-12-16 Buy
AvaChem 2203 Tandutinib 100mg $269 2021-12-16 Buy
AvaChem 2203 Tandutinib 1g $890 2021-12-16 Buy
Biosynth Carbosynth FT28001 Tandutinib 10mg $45 2021-12-16 Buy
Biosynth Carbosynth FT28001 Tandutinib 50mg $158 2021-12-16 Buy
Cayman Chemical 12098 Tandutinib ≥95% 25mg $56 2024-03-01 Buy
Cayman Chemical 12098 Tandutinib ≥95% 50mg $93 2024-03-01 Buy
Cayman Chemical 12098 Tandutinib ≥95% 100mg $140 2024-03-01 Buy
Cayman Chemical 12098 Tandutinib ≥95% 250mg $311 2024-03-01 Buy
ChemScene CS-0128 Tandutinib 99.48% 50mg $60 2021-12-16 Buy
ChemScene CS-0128 Tandutinib 99.48% 100mg $96 2021-12-16 Buy
ChemScene CS-0128 Tandutinib 99.48% 200mg $168 2021-12-16 Buy

Properties

Melting point :177-178°C
Boiling point :769.5±60.0 °C(Predicted)
Density :1.213±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :13.39±0.70(Predicted)
form :Solid
color :White to Off-White
CAS DataBase Reference :387867-13-2(CAS DataBase Reference)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Tandutinib is a potent antagonist of platelet-derived growth factor receptor β (PDGFRβ), FLT3, and c-Kit (IC50 = 200, 220, and 170 nM, respectively). It less potently inhibits macrophage colony-stimulating factor 1 receptor (IC50 = 3.4 μM) and does not significantly inhibit other tyrosine or serine/threonine kinases. Tandutinib blocks the growth of cells expressing an internal tandem duplication within the juxtamembrane domain of the FLT3 receptor, found in some acute myelogenous leukemia cells. It also impairs the growth of colon cancer cells through its actions on the c-Kit receptor. Tandutinib reverses multidrug resistance in vitro by impairing the efflux activity of the multidrug resistance protein 7.

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