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ChemicalBook >> CAS DataBase List >> Masitinib

Masitinib

Masitinib price.
  • $29 - $1440
  • Product name: Masitinib
  • CAS: 790299-79-5
  • MF: C28H30N6OS
  • MW: 498.64
  • EINECS:226-164-5
  • MDL Number:MFCD09954132
  • Synonyms:MASITINIB;4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide;4-((4-Methylpiperazin-1-yl)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)-1,3-thiazol-2-yl)amino)phenyl)benzamide;Ab 1010;Ab1010;Ab-1010;Mastinib;Masitinib(AB1010)
31 prices
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Brand
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • TRC
Package
  • 10mg
  • 20mg
  • 25mg
  • 50MG
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 1000mg
  • 2g
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1053-M010
  • Product descriptionMasatinib ≥95%
  • Packaging10mg
  • Price$97
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberA821
  • Product descriptionMasitinib
  • Packaging100mg
  • Price$161
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0025916
  • Product descriptionMASITINIB 95.00%
  • Packaging50MG
  • Price$808.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0025916
  • Product descriptionMASITINIB 95.00%
  • Packaging10MG
  • Price$216.3
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2942
  • Product descriptionMasitinib(AB1010)
  • Packaging25mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60373
  • Product descriptionMasitinib(AB1010) ≥98%
  • Packaging20mg
  • Price$188
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2645
  • Product descriptionMasitinib
  • Packaging10mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2645
  • Product descriptionMasitinib
  • Packaging25mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2645
  • Product descriptionMasitinib
  • Packaging100mg
  • Price$109
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2645
  • Product descriptionMasitinib
  • Packaging1g
  • Price$395
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181285
  • Product descriptionMastinib >98%
  • Packaging1000mg
  • Price$912.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181285
  • Product descriptionMastinib >98%
  • Packaging250mg
  • Price$606.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181285
  • Product descriptionMastinib >98%
  • Packaging100mg
  • Price$397.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM65073
  • Product descriptionMasitinib
  • Packaging50mg
  • Price$194
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM65073
  • Product descriptionMasitinib
  • Packaging10mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13105
  • Product descriptionMasitinib ≥98%
  • Packaging10mg
  • Price$68
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1053-M010 Masatinib ≥95% 10mg $97 2021-12-16 Buy
AK Scientific A821 Masitinib 100mg $161 2021-12-16 Buy
American Custom Chemicals Corporation API0025916 MASITINIB 95.00% 50MG $808.5 2021-12-16 Buy
American Custom Chemicals Corporation API0025916 MASITINIB 95.00% 10MG $216.3 2021-12-16 Buy
ApexBio Technology A2942 Masitinib(AB1010) 25mg $100 2021-12-16 Buy
Arctom CFN60373 Masitinib(AB1010) ≥98% 20mg $188 2021-12-16 Buy
AvaChem 2645 Masitinib 10mg $29 2021-12-16 Buy
AvaChem 2645 Masitinib 25mg $59 2021-12-16 Buy
AvaChem 2645 Masitinib 100mg $109 2021-12-16 Buy
AvaChem 2645 Masitinib 1g $395 2021-12-16 Buy
Biorbyt Ltd orb181285 Mastinib >98% 1000mg $912.9 2021-12-16 Buy
Biorbyt Ltd orb181285 Mastinib >98% 250mg $606.9 2021-12-16 Buy
Biorbyt Ltd orb181285 Mastinib >98% 100mg $397.8 2021-12-16 Buy
Biosynth Carbosynth FM65073 Masitinib 50mg $194 2021-12-16 Buy
Biosynth Carbosynth FM65073 Masitinib 10mg $55 2021-12-16 Buy
Cayman Chemical 13105 Masitinib ≥98% 10mg $68 2024-03-01 Buy

Properties

Melting point :90-95°C
Density :1.280±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :13.24±0.70(Predicted)
color :Off-White to Pale Beige

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P314 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Masitinib is a tyrosine kinase, c-Kit, PDGFR, FGFR3, and FAK pathway inhibitor with IC50 of 150 ± 80, 200 ± 40 nM for KIT tyrosine phosphorylation and the recombinant wild-type KIT. Masitinib can enhance the antiproliferative effects of gemcitabine (GEM) in pancreatic cancer cells. Masitinib potently inhibits KIT with activating mutations in the juxtamembrane domain.

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