ML234
- $32 - $593
- Product name: ML234
- CAS: 1222800-79-4
- MF: C21H23N3O2
- MW: 349.43
- EINECS:
- MDL Number:MFCD28053518
- Synonyms:ML234;ML324;N-[3-(Dimethylamino)propyl]-4-(8-hydroxy-6-quinolinyl)benzamide;NCGC00183808-01;ML324(CID-44143209);CS-2198;ML-324;ML324;ML 324;Benzamide, N-[3-(dimethylamino)propyl]-4-(8-hydroxy-6-quinolinyl)-
23 prices
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Brand
- AK Scientific
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 200mg
- 10mM(in 1mL DMSO)
- 100mg
- ManufacturerAK Scientific
- Product number3882AH
- Product descriptionN-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide
- Packaging10mg
- Price$168
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3882AH
- Product descriptionN-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide
- Packaging50mg
- Price$404
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4891
- Product descriptionML324
- Packaging10mM(in 1mL DMSO)
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4891
- Product descriptionML324
- Packaging10mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4891
- Product descriptionML324
- Packaging50mg
- Price$222
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4891
- Product descriptionML324
- Packaging200mg
- Price$593
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545907
- Product descriptionML-324 >98%
- Packaging5mg
- Price$154.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545907
- Product descriptionML-324 >98%
- Packaging25mg
- Price$357
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17472
- Product descriptionML-324 ≥95%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17472
- Product descriptionML-324 ≥95%
- Packaging5mg
- Price$70
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17472
- Product descriptionML-324 ≥95%
- Packaging10mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17472
- Product descriptionML-324 ≥95%
- Packaging25mg
- Price$230
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM248314
- Product descriptionN-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide 98%
- Packaging100mg
- Price$404
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3993
- Product descriptionML324 98.60%
- Packaging10mg
- Price$94
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3993
- Product descriptionML324 98.60%
- Packaging50mg
- Price$306
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3993
- Product descriptionML324 98.60%
- Packaging100mg
- Price$540
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 3882AH | N-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide | 10mg | $168 | 2021-12-16 | Buy |
AK Scientific | 3882AH | N-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide | 50mg | $404 | 2021-12-16 | Buy |
ApexBio Technology | B4891 | ML324 | 10mM(in 1mL DMSO) | $60 | 2021-12-16 | Buy |
ApexBio Technology | B4891 | ML324 | 10mg | $68 | 2021-12-16 | Buy |
ApexBio Technology | B4891 | ML324 | 50mg | $222 | 2021-12-16 | Buy |
ApexBio Technology | B4891 | ML324 | 200mg | $593 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545907 | ML-324 >98% | 5mg | $154.7 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545907 | ML-324 >98% | 25mg | $357 | 2021-12-16 | Buy |
Cayman Chemical | 17472 | ML-324 ≥95% | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 17472 | ML-324 ≥95% | 5mg | $70 | 2024-03-01 | Buy |
Cayman Chemical | 17472 | ML-324 ≥95% | 10mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 17472 | ML-324 ≥95% | 25mg | $230 | 2024-03-01 | Buy |
Chemenu | CM248314 | N-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide 98% | 100mg | $404 | 2021-12-16 | Buy |
ChemScene | CS-3993 | ML324 98.60% | 10mg | $94 | 2021-12-16 | Buy |
ChemScene | CS-3993 | ML324 98.60% | 50mg | $306 | 2021-12-16 | Buy |
ChemScene | CS-3993 | ML324 98.60% | 100mg | $540 | 2021-12-16 | Buy |
Properties
Melting point :>187oC (dec.)
Boiling point :590.1±50.0 °C(Predicted)
Density :1.188±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :4.71±0.40(Predicted)
form :powder
color :white to light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Boiling point :590.1±50.0 °C(Predicted)
Density :1.188±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :4.71±0.40(Predicted)
form :powder
color :white to light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Safety Information
Symbol(GHS): | |||||||||||||||
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Signal word: | Warning | ||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
The family of Jumonji domain containing histone demethylases 2 (JMJD2s, also known as KDM4s) demethylates lysines 9 and 36 on histone 3, resulting in the repression of specific mammalian and viral genes. ML-324 is a cell-permeable inhibitor of JMJD2E (KDM4DL; IC50 = 920 nM) that is inactive against lysine-specific demethylase, LSD1. It reduces the expression of immediate early genes of Herpes simplex virus (IC50 = ~10 μM) and human cytomegalovirus, blocks viral infection, and suppresses the level of viral reactivation in a ganglia explant model of latently infected mice. The effects of ML-324 are reversible, as viral replication resumes after drug withdrawal.Related product price
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