ML216
|
- $32 - $2250
- Product name: ML216
- CAS: 1430213-30-1
- MF: C15H9F4N5OS
- MW: 383.32
- EINECS:
- MDL Number:MFCD24849400
- Synonyms:ML216;1-(4-Fluoro-3-(trifluoromethyl)phenyl)-3-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)urea;N-[4-Fluoro-3-(trifluoromethyl)phenyl]-N'-[5-(4-pyridinyl)-1,3,4-thiadiazol-2-yl]urea;CID 49852229;CID49852229;CID-49852229;ML 216; ML-216; CID-49852229; CID49852229; CID 49852229;CS-1561
25 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 1mg
- 25mg
- 250mg
- 1g
- 10mM(in 1mL DMSO)
- 5mg
- 10mg
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product numberSYN5288
- Product descriptionML216
- Packaging50mg
- Price$406
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5288
- Product descriptionML216
- Packaging100mg
- Price$688
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA522753
- Product descriptionML216 98+%
- Packaging5mg
- Price$52
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA522753
- Product descriptionML216 98+%
- Packaging10mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB8015
- Product descriptionML216
- Packaging5mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB8015
- Product descriptionML216
- Packaging10mM(in 1mL DMSO)
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB8015
- Product descriptionML216
- Packaging10mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15186
- Product descriptionML-216 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15186
- Product descriptionML-216 ≥98%
- Packaging5mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15186
- Product descriptionML-216 ≥98%
- Packaging10mg
- Price$120
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15186
- Product descriptionML-216 ≥98%
- Packaging25mg
- Price$267
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-3352
- Product descriptionML216 99.77%
- Packaging5mg
- Price$66
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3352
- Product descriptionML216 99.77%
- Packaging10mg
- Price$114
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3352
- Product descriptionML216 99.77%
- Packaging25mg
- Price$228
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3352
- Product descriptionML216 99.77%
- Packaging50mg
- Price$336
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003516
- Product descriptionML216 98+%
- Packaging50mg
- Price$210
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5288 | ML216 | 50mg | $406 | 2021-12-16 | Buy |
| AK Scientific | SYN5288 | ML216 | 100mg | $688 | 2021-12-16 | Buy |
| Ambeed | A522753 | ML216 98+% | 5mg | $52 | 2021-12-16 | Buy |
| Ambeed | A522753 | ML216 98+% | 10mg | $95 | 2021-12-16 | Buy |
| ApexBio Technology | B8015 | ML216 | 5mg | $55 | 2021-12-16 | Buy |
| ApexBio Technology | B8015 | ML216 | 10mM(in 1mL DMSO) | $70 | 2021-12-16 | Buy |
| ApexBio Technology | B8015 | ML216 | 10mg | $95 | 2021-12-16 | Buy |
| Cayman Chemical | 15186 | ML-216 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 15186 | ML-216 ≥98% | 5mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 15186 | ML-216 ≥98% | 10mg | $120 | 2024-03-01 | Buy |
| Cayman Chemical | 15186 | ML-216 ≥98% | 25mg | $267 | 2024-03-01 | Buy |
| ChemScene | CS-3352 | ML216 99.77% | 5mg | $66 | 2021-12-16 | Buy |
| ChemScene | CS-3352 | ML216 99.77% | 10mg | $114 | 2021-12-16 | Buy |
| ChemScene | CS-3352 | ML216 99.77% | 25mg | $228 | 2021-12-16 | Buy |
| ChemScene | CS-3352 | ML216 99.77% | 50mg | $336 | 2021-12-16 | Buy |
| Crysdot | CD31003516 | ML216 98+% | 50mg | $210 | 2021-12-16 | Buy |
Properties
Density :1.583±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO:29.0(Max Conc. mg/mL);75.65(Max Conc. mM)
pka :6.40±0.50(Predicted)
form :powder
color :light orange to dark orange
storage temp. :2-8°C
solubility :DMSO:29.0(Max Conc. mg/mL);75.65(Max Conc. mM)
pka :6.40±0.50(Predicted)
form :powder
color :light orange to dark orange
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Bloom (BLM) helicase is a DNA unwinding enzyme important for DNA repair in the homologous recombination pathway. Mutations of the BLM gene result in reduced BLM helicase activity that is associated with the rare genetic disorder, Bloom’s Syndrome, and a predisposition to developing cancer. ML-216 is the first identified small molecule inhibitor of BLM helicase (IC50 = 1.8 μM) that is 28-fold selective against the related helicases RECQ1, RECQ5, and E. coli UvrD (IC50s ≥ 50 μM). At 25-50 μM, ML-216 has been shown to dose-dependently inhibit the proliferation of BLM-expressing PSNF5 fibroblast cells but not BLM-deficient PSNG13 fibroblast cells.Related product price
- N-METHYLBENZAMIDE
$7-1158.18 - N-Methyl pyrrole
$5-4137.09 - 2-Methylaminoethanol
$10-1166.55
