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ChemicalBook >> CAS DataBase List >> Letrozole

Letrozole

Letrozole price.
  • $43 - $1290
  • Product name: Letrozole
  • CAS: 112809-51-5
  • MF: C17H11N5
  • MW: 285.3
  • EINECS:675-034-8
  • MDL Number:MFCD00866241
  • Synonyms:Letrozole99%;CGS-20267, Femara;letrozolex;Lelrozol;1-[BIS(4-CYANOPHENYL)METHYL]-1,2,4-TRIAZOLE;4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile;4,4'-(1H-1,2,4-Triazole-1-ylmethylene)bisbenzonitrile;4,4'-[(1H-1,2,4-Triazole-1-yl)methylene]dibenzonitrile
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  • 10
  • 10mM(in 1mL DMSO)
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  • ManufacturerAbosyn
  • Product number30-1150
  • Product descriptionLetrozole 95%-98%
  • Packaging1g
  • Price$310
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1284
  • Product descriptionLetrozole 98%
  • Packaging0.5g
  • Price$620
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH020
  • Product descriptionLetrozole
  • Packaging1g
  • Price$241
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1307
  • Product descriptionLetrozole
  • Packaging10mM(in 1mL DMSO)
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1307
  • Product descriptionLetrozole
  • Packaging100mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60262
  • Product descriptionLetrozole
  • Packaging20mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2033
  • Product descriptionLetrozole
  • Packaging100mg
  • Price$49
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number2033
  • Product descriptionLetrozole
  • Packaging1g
  • Price$129
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number2033
  • Product descriptionLetrozole
  • Packaging10g
  • Price$690
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2033
  • Product descriptionLetrozole
  • Packaging25g
  • Price$1290
  • Updated2021-12-16
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  • ManufacturerAxon Medchem
  • Product numberAxon3257
  • Product descriptionLetrozole-CGS20267 99%
  • Packaging50mg
  • Price$66
  • Updated2021-12-16
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  • ManufacturerAxon Medchem
  • Product numberAxon3257
  • Product descriptionLetrozole-CGS20267 99%
  • Packaging2x50mg
  • Price$110
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb134719
  • Product descriptionLetrozole >99%
  • Packaging100mg
  • Price$397.8
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb134719
  • Product descriptionLetrozole >99%
  • Packaging250mg
  • Price$510
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb134719
  • Product descriptionLetrozole >99%
  • Packaging1g
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBL164620
  • Product descriptionLetrozole
  • Packaging50mg
  • Price$43
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Abosyn 30-1150 Letrozole 95%-98% 1g $310 2021-12-16 Buy
AHH API-1284 Letrozole 98% 0.5g $620 2021-12-16 Buy
AK Scientific H020 Letrozole 1g $241 2021-12-16 Buy
ApexBio Technology A1307 Letrozole 10mM(in 1mL DMSO) $80 2021-12-16 Buy
ApexBio Technology A1307 Letrozole 100mg $100 2021-12-16 Buy
Arctom CFN60262 Letrozole 20mg $70 2021-12-16 Buy
AvaChem 2033 Letrozole 100mg $49 2021-12-16 Buy
AvaChem 2033 Letrozole 1g $129 2021-12-16 Buy
AvaChem 2033 Letrozole 10g $690 2021-12-16 Buy
AvaChem 2033 Letrozole 25g $1290 2021-12-16 Buy
Axon Medchem Axon3257 Letrozole-CGS20267 99% 50mg $66 2021-12-16 Buy
Axon Medchem Axon3257 Letrozole-CGS20267 99% 2x50mg $110 2021-12-16 Buy
Biorbyt Ltd orb134719 Letrozole >99% 100mg $397.8 2021-12-16 Buy
Biorbyt Ltd orb134719 Letrozole >99% 250mg $510 2021-12-16 Buy
Biorbyt Ltd orb134719 Letrozole >99% 1g $765 2021-12-16 Buy
Biosynth Carbosynth BL164620 Letrozole 50mg $43 2021-12-16 Buy

Properties

Melting point :181-183°C
Boiling point :563.5±60.0 °C(Predicted)
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >50mg/mL
pka :1.52±0.11(Predicted)
form :White powder
color :white to off-white
Merck :14,5450
InChI :InChI=1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H
InChIKey :HPJKCIUCZWXJDR-UHFFFAOYSA-N
SMILES :C(C1=CC=C(C=C1)C#N)(C1=CC=C(C=C1)C#N)N1C=NC=N1
CAS DataBase Reference :112809-51-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Letrozole (trade name: Femara) is an orally active nonsteroidal aromatase inhibitor. As a competitive inhibitor of the aromatase, Letrozole inhibits the conversion of androgens to estrogen (estrogen stimulates breast tissues and breast cancer reoccurrence) and gonadal steroidogenesis. It can be used for the treatment of breast cancer that is hormonally-responsive or has an unknown receptor status in postmenopausal women. Besides this, Letrozole also has some off-label use such as ovarian stimulation, pretreatment of termination of pregnancy, treatment of gynecomastia, treatment of endometriosis, and promoting spermatogenesis for male patients of nonobstructive azoospermia.

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