Letrozole NEW
Price | $25 |
Package | 1box |
Min. Order: | 1box |
Supply Ability: | 10000box |
Update Time: | 2024-05-15 |
Product Details
Product Name: Letrozole | CAS No.: 112809-51-5 |
EC-No.: 1806241-263-5 | Min. Order: 1box |
Purity: 99% | Supply Ability: 10000box |
Release date: 2024/05/15 |
Chinese name: Letrozole
English name: Letrozole
CAS: 112809-51-5
Molecular formula: C17H11N5
MDL number: MFCD00866241
Molecular weight: 285.3
Appearance: White or white powder
Appearance: Melting point 181 ~ 183℃
Melting point: 181-183°C
Boiling point: 563.5±60.0 °C(Predicted)
Density: 1.21± 0.1g /cm3(Predicted)
Storage conditions: 2-8°C
Solubility: dimethyl sulfoxide: >50mg/mL
Acidity coefficient (pKa) : 1.52±0.11(Predicted)
Form: White powder
Color: White to off-white
Merck: 14,5450
InChI: InChI = 1 s/C17H11N5 / c18-9-13-1-5-15 17 (22-12-20-22-12-20) (6-2-13) 16-7-3-14 (10-19)/h1-4-8-16 8, 11-12 H
InChIKey: HPJKCIUCZWXJDR-UHFFFAOYSA-N
SMILES: C (C1 = CC = C (C = C1) C # N) (C1 = CC = C (C = C1) C # N) N1C = NC = N1
Use 1
Pyrrole aromatization enzyme inhibitors. Used to treat breast cancer.
Preparation method
4-bromomethyl benzonitrile (I) reacts with triazole in chloroforme-acetonitrile, and the resulting product (II) reacts with 4-fluoronitrile in dimethylformamide in the presence of potassium tert-butanol to obtain letrozole.
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- Since: 2024-01-19
- Address: Hong Kong