Bardoxolone methyl
|
- $30 - $1802
- Product name: Bardoxolone methyl
- CAS: 218600-53-4
- MF: C32H43NO4
- MW: 505.69
- EINECS:606-850-4
- MDL Number:MFCD11983137
- Synonyms:NSC 713200;Bardoxolone Me ester;Bardoxolone Methyl (RTA 402);Oleana-1,9(11)-dien-28-oic acid, 2-cyano-3,12-dioxo-, methyl ester;TP-155;Methyl 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid methyl ester;2-Cyano-3,12-dioxoolean-1,9(11)-dien-28-oic acid methyl ester;(4aS,6aR,6bS,8aR,12aS,14aR,14bS)-methyl 11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicene-4a-carboxylate
30 prices
Selected condition：
Brand
- Abosyn
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 5MG
- 2x5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 50
- 10
- 1g
- ManufacturerAbosyn
- Product number61-5874
- Product description(4aS,6aR,6bS,8aR,12aS,14bS)-methyl11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicene-4a-carboxylate 95+%
- Packaging1g
- Price$700
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007311
- Product descriptionBARDOXOLONE METHYL 95.00%
- Packaging5MG
- Price$501.12
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3221
- Product descriptionBardoxolonemethyl
- Packaging500mg
- Price$657
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1772
- Product descriptionCDDO-Me-Bardoxolonemethyl|RTA402 98%
- Packaging2x5mg
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146173
- Product descriptionBardoxolone methyl >99%
- Packaging100mg
- Price$569.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146173
- Product descriptionBardoxolone methyl >99%
- Packaging250mg
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146173
- Product descriptionBardoxolone methyl >99%
- Packaging1g
- Price$1802
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB15804
- Product descriptionBardoxolone methyl
- Packaging10mg
- Price$69
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB15804
- Product descriptionBardoxolone methyl
- Packaging25mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB15804
- Product descriptionBardoxolone methyl
- Packaging50mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB15804
- Product descriptionBardoxolone methyl
- Packaging100mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB15804
- Product descriptionBardoxolone methyl
- Packaging250mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11883
- Product descriptionCDDO methyl ester ≥98%
- Packaging1mg
- Price$30
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number11883
- Product descriptionCDDO methyl ester ≥98%
- Packaging5mg
- Price$58
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11883
- Product descriptionCDDO methyl ester ≥98%
- Packaging10mg
- Price$99
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11883
- Product descriptionCDDO methyl ester ≥98%
- Packaging50mg
- Price$319
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Abosyn | 61-5874 | (4aS,6aR,6bS,8aR,12aS,14bS)-methyl11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicene-4a-carboxylate 95+% | 1g | $700 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007311 | BARDOXOLONE METHYL 95.00% | 5MG | $501.12 | 2021-12-16 | Buy |
| ApexBio Technology | A3221 | Bardoxolonemethyl | 500mg | $657 | 2021-12-16 | Buy |
| Axon Medchem | Axon1772 | CDDO-Me-Bardoxolonemethyl|RTA402 98% | 2x5mg | $132 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146173 | Bardoxolone methyl >99% | 100mg | $569.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146173 | Bardoxolone methyl >99% | 250mg | $765 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146173 | Bardoxolone methyl >99% | 1g | $1802 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB15804 | Bardoxolone methyl | 10mg | $69 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB15804 | Bardoxolone methyl | 25mg | $125 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB15804 | Bardoxolone methyl | 50mg | $190 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB15804 | Bardoxolone methyl | 100mg | $280 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB15804 | Bardoxolone methyl | 250mg | $500 | 2021-12-16 | Buy |
| Cayman Chemical | 11883 | CDDO methyl ester ≥98% | 1mg | $30 | 2023-06-20 | Buy |
| Cayman Chemical | 11883 | CDDO methyl ester ≥98% | 5mg | $58 | 2024-03-01 | Buy |
| Cayman Chemical | 11883 | CDDO methyl ester ≥98% | 10mg | $99 | 2024-03-01 | Buy |
| Cayman Chemical | 11883 | CDDO methyl ester ≥98% | 50mg | $319 | 2024-03-01 | Buy |
Properties
Melting point :215-223°C
Boiling point :600.8±55.0 °C(Predicted)
Density :1.15
storage temp. :Refrigerator
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
color :White to Light Brown
InChIKey :WPTTVJLTNAWYAO-KPOXMGGZSA-N
SMILES :C1(=O)[C@@]([C@]2([C@](C)(C=C1C#N)C1[C@@]([C@]3([C@@](C(=O)C=1)([H])[C@]1([C@@](CC[C@](C1)(C)C)(C(OC)=O)CC3)[H])C)(C)CC2)[H])(C)C
CAS DataBase Reference :218600-53-4
Boiling point :600.8±55.0 °C(Predicted)
Density :1.15
storage temp. :Refrigerator
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
color :White to Light Brown
InChIKey :WPTTVJLTNAWYAO-KPOXMGGZSA-N
SMILES :C1(=O)[C@@]([C@]2([C@](C)(C=C1C#N)C1[C@@]([C@]3([C@@](C(=O)C=1)([H])[C@]1([C@@](CC[C@](C1)(C)C)(C(OC)=O)CC3)[H])C)(C)CC2)[H])(C)C
CAS DataBase Reference :218600-53-4
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
The synthetic oleanane triterpenoid CDDO is a Nrf2 activator that inhibits proliferation and induces differentiation and apoptosis in various cancer cells. The C-28 methyl ester of CDDO (CDDO methyl ester) blocks the cellular synthesis of inducible nitric oxide synthase (iNOS) and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.11 nM. It induces apoptosis, induces differentiation, and inhibits the inflammatory response in various tumor cells through inhibition of IκBα kinase/NF-κB signaling. CDDO methyl ester has potent antidiabetic activity, reducing proinflammatory cytokine expression in high fat diet-fed type 2 diabetic mice and in Leprdb/db mice and triggering AMP-activated protein kinase and LKB1 activation in muscle and liver.Related product price
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