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ChemicalBook >> CAS DataBase List >> Volasertib (BI 6727)

Volasertib (BI 6727)

Volasertib (BI 6727) price.
  • $24 - $2245.7
  • Product name: Volasertib (BI 6727)
  • CAS: 755038-65-4
  • MF: C34H50N8O3
  • MW: 618.81
  • EINECS:813-258-1
  • MDL Number:MFCD20926414
  • Synonyms:N-[trans-4-[4-(Cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-4-[[(7R)-7-ethyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6-oxo-2-pteridinyl]amino]-3-methoxybenzamide;N-(Trans-4-(4-(cyclopropylMethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-Methyl-6-oxo-5,6,7;VOLASERTIB (BI 6727);BI 6727;BI-6727;BI6727;BI6727 (Volasertib);N-[trans-4-[4-(CyclopropylMethyl)-1-piperazinyl]cyclohexyl]-4-[[(7R)-7-ethyl-5,6,7,8-tetrahydro-5-Me;N-((1r,4R)-4-(4-(cyclopropylMethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-Methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)aMino)-3-MethoxybenzaMide;Volasertib (BI 6727);N-(Trans-4-(4-(cyclopropylMethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-Methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)aMino)-3-MethoxybenzaMide
30 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberX7437
  • Product descriptionVolasertib
  • Packaging2mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA232139
  • Product descriptionN-(trans-4-(4-(Cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamide 98%
  • Packaging1mg
  • Price$24
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA232139
  • Product descriptionN-(trans-4-(4-(Cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamide 98%
  • Packaging5mg
  • Price$41
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA232139
  • Product descriptionN-(trans-4-(4-(Cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamide 98%
  • Packaging10mg
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA232139
  • Product descriptionN-(trans-4-(4-(Cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamide 98%
  • Packaging50mg
  • Price$89
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA232139
  • Product descriptionN-(trans-4-(4-(Cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamide 98%
  • Packaging100mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA232139
  • Product descriptionN-(trans-4-(4-(Cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamide 98%
  • Packaging250mg
  • Price$232
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA232139
  • Product descriptionN-(trans-4-(4-(Cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamide 98%
  • Packaging1g
  • Price$581
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000713
  • Product descriptionBI-6727 95.00%
  • Packaging5MG
  • Price$498.92
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8558
  • Product descriptionBI6727(Volasertib)
  • Packaging5mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8558
  • Product descriptionBI6727(Volasertib)
  • Packaging10mM(in 1mL DMSO)
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8558
  • Product descriptionBI6727(Volasertib)
  • Packaging10mg
  • Price$158
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8558
  • Product descriptionBI6727(Volasertib)
  • Packaging50mg
  • Price$484
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8558
  • Product descriptionBI6727(Volasertib)
  • Packaging100mg
  • Price$792
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60201
  • Product descriptionVolasertib(BI6727)
  • Packaging10mg
  • Price$338
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1473
  • Product descriptionBI6727-Volasertib 99%
  • Packaging5mg
  • Price$137.5
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X7437 Volasertib 2mg $116 2021-12-16 Buy
Ambeed A232139 N-(trans-4-(4-(Cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamide 98% 1mg $24 2021-12-16 Buy
Ambeed A232139 N-(trans-4-(4-(Cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamide 98% 5mg $41 2021-12-16 Buy
Ambeed A232139 N-(trans-4-(4-(Cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamide 98% 10mg $53 2021-12-16 Buy
Ambeed A232139 N-(trans-4-(4-(Cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamide 98% 50mg $89 2021-12-16 Buy
Ambeed A232139 N-(trans-4-(4-(Cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamide 98% 100mg $116 2021-12-16 Buy
Ambeed A232139 N-(trans-4-(4-(Cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamide 98% 250mg $232 2021-12-16 Buy
Ambeed A232139 N-(trans-4-(4-(Cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-(((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzamide 98% 1g $581 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000713 BI-6727 95.00% 5MG $498.92 2021-12-16 Buy
ApexBio Technology A8558 BI6727(Volasertib) 5mg $88 2021-12-16 Buy
ApexBio Technology A8558 BI6727(Volasertib) 10mM(in 1mL DMSO) $140 2021-12-16 Buy
ApexBio Technology A8558 BI6727(Volasertib) 10mg $158 2021-12-16 Buy
ApexBio Technology A8558 BI6727(Volasertib) 50mg $484 2021-12-16 Buy
ApexBio Technology A8558 BI6727(Volasertib) 100mg $792 2021-12-16 Buy
Arctom CFN60201 Volasertib(BI6727) 10mg $338 2021-12-16 Buy
Axon Medchem Axon1473 BI6727-Volasertib 99% 5mg $137.5 2021-12-16 Buy

Properties

Melting point :86 - 87*C
Density :1.26
storage temp. :-20°
solubility :Soluble in DMSO (up to at least 25 mg/ml).
form :solid
pka :14.26±0.40(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
CAS DataBase Reference :755038-65-4

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Volasertib (BI 6727) is a highly potent Plk1 inhibitor with IC50 of 0.87 nM in a cell-free assay. It shows 6-and 65-fold greater selectivity against Plk2 and Plk3. Phase 3.