5-Azacytidine
- $7 - $1767.15
- Product name: 5-Azacytidine
- CAS: 320-67-2
- MF: C8H12N4O5
- MW: 244.2
- EINECS:206-280-2
- MDL Number:MFCD00006539
- Synonyms:Antibiotic U 18496-15N4;Azacitidine-15N4;Azacytidine-15N4;LadakaMycin-15N4;LedakaMycin-15N4;Mylosar-15N4;NSC 102816-15N4;NSC 103-627-15N4
63 prices
Selected condition:
Brand
- Abosyn
- Adipogen Life Sciences
- AK Scientific
- Alfa Aesar
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- CSNpharm
- DC Chemicals
- JR MediChem
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 5MG
- 20mg
- 50mg
- 100mg
- 150mg
- 250mg
- 300mg
- 2g
- 5g
- 1g
- 50
- 10mM(in 1mL DMSO)
- 10g
- 25g
- 50g
- 1vial
- 100G
- ManufacturerAbosyn
- Product number61-11867
- Product description4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one 95-98%
- Packaging1g
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-A0271-G001
- Product description5-Azacytidine ≥98%(HPLC)
- Packaging1g
- Price$171
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ10124
- Product description5-Azacytidine
- Packaging1g
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64159
- Product description5-Azacytidine, 98%
- Packaging1g
- Price$63.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64159
- Product description5-Azacytidine, 98%
- Packaging5g
- Price$245.65
- Updated2024-03-01
- Buy
- ManufacturerAmbeed
- Product numberA386837
- Product description5-Azacytidine 95+%
- Packaging100mg
- Price$7
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA386837
- Product description5-Azacytidine 95+%
- Packaging250mg
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA386837
- Product description5-Azacytidine 95+%
- Packaging1g
- Price$23
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA386837
- Product description5-Azacytidine 95+%
- Packaging5g
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA386837
- Product description5-Azacytidine 95+%
- Packaging25g
- Price$324
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003444
- Product descriptionMYLOSAR 95.00%
- Packaging5MG
- Price$514
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003444
- Product descriptionMYLOSAR 95.00%
- Packaging1G
- Price$825
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003444
- Product descriptionMYLOSAR 95.00%
- Packaging5G
- Price$1767.15
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1907
- Product description5-Azacytidine
- Packaging250mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1907
- Product description5-Azacytidine
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1907
- Product description5-Azacytidine
- Packaging1g
- Price$175
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Abosyn | 61-11867 | 4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one 95-98% | 1g | $75 | 2021-12-16 | Buy |
Adipogen Life Sciences | CDX-A0271-G001 | 5-Azacytidine ≥98%(HPLC) | 1g | $171 | 2021-12-16 | Buy |
AK Scientific | J10124 | 5-Azacytidine | 1g | $80 | 2021-12-16 | Buy |
Alfa Aesar | J64159 | 5-Azacytidine, 98% | 1g | $63.65 | 2024-03-01 | Buy |
Alfa Aesar | J64159 | 5-Azacytidine, 98% | 5g | $245.65 | 2024-03-01 | Buy |
Ambeed | A386837 | 5-Azacytidine 95+% | 100mg | $7 | 2021-12-16 | Buy |
Ambeed | A386837 | 5-Azacytidine 95+% | 250mg | $10 | 2021-12-16 | Buy |
Ambeed | A386837 | 5-Azacytidine 95+% | 1g | $23 | 2021-12-16 | Buy |
Ambeed | A386837 | 5-Azacytidine 95+% | 5g | $90 | 2021-12-16 | Buy |
Ambeed | A386837 | 5-Azacytidine 95+% | 25g | $324 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0003444 | MYLOSAR 95.00% | 5MG | $514 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0003444 | MYLOSAR 95.00% | 1G | $825 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0003444 | MYLOSAR 95.00% | 5G | $1767.15 | 2021-12-16 | Buy |
ApexBio Technology | A1907 | 5-Azacytidine | 250mg | $55 | 2021-12-16 | Buy |
ApexBio Technology | A1907 | 5-Azacytidine | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
ApexBio Technology | A1907 | 5-Azacytidine | 1g | $175 | 2021-12-16 | Buy |
Properties
Melting point :226-232 °C (dec.)(lit.)
alpha :40 º (C=1, H2O 22 ºC)
Boiling point :387.12°C (rough estimate)
Density :1.4287 (rough estimate)
refractive index :1.6590 (estimate)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml), or in Water (up to 12 mg/ml).
pka :13.46±0.70(Predicted)
form :lyophilized powder
color :White to Off-white
Water Solubility :0.5-1.0 g/100 mL at 21 ºC
Merck :14,887
BRN :620461
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
InChIKey :NMUSYJAQQFHJEW-WGDKFINWSA-N
LogP :-2.191 (est)
CAS DataBase Reference :320-67-2(CAS DataBase Reference)
IARC :2A (Vol. 50) 1990
EPA Substance Registry System :Azacitidine (320-67-2)
alpha :40 º (C=1, H2O 22 ºC)
Boiling point :387.12°C (rough estimate)
Density :1.4287 (rough estimate)
refractive index :1.6590 (estimate)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml), or in Water (up to 12 mg/ml).
pka :13.46±0.70(Predicted)
form :lyophilized powder
color :White to Off-white
Water Solubility :0.5-1.0 g/100 mL at 21 ºC
Merck :14,887
BRN :620461
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
InChIKey :NMUSYJAQQFHJEW-WGDKFINWSA-N
LogP :-2.191 (est)
CAS DataBase Reference :320-67-2(CAS DataBase Reference)
IARC :2A (Vol. 50) 1990
EPA Substance Registry System :Azacitidine (320-67-2)
Safety Information
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Description
5-Azacytidine, a chemical analogue of the DNA and RNA nucleoside cytidine, is an inhibitor of DNA methyltransferases, potentially serving to reverse epigenetic changes. It reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes (IC50s = 2.4 and 2.6 μM for in vitro anti-myeloma activity) and cancer (IC50s ~ 0.4 μM for inhibiting proliferation of various cancer cell lines). 5-Azacytidine has a reported half-life of 17 hours and is considerably cytotoxic; it must be incorporated into DNA to covalently trap DNA methyltransferases.More related product prices
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Suppliers and manufacturers
Wuhu Nuowei chemistry Co., Ltd.
Capot Chemical Co.,Ltd.
Shanghai Daken Advanced Materials Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.