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ChemicalBook >> CAS DataBase List >> AZD-8055

AZD-8055

AZD-8055 price.
  • $26 - $2395.3
  • Product name: AZD-8055
  • CAS: 1009298-09-2
  • MF: C25H31N5O4
  • MW: 465.54
  • EINECS:-0
  • MDL Number:MFCD16660191
  • Synonyms:AZD 8055 [5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol;AZD8055, >=98%;Propanoic acid, 2,2-dimethyl-, [5-(2,4-dichloropyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl]methyl ester;(5-{2,4-dichloropyrido[2,3-d]pyriMidin-7-yl}-2-Methoxyphenyl)Methyl 2,2-diMethylpropanoate;[5-[2,4-Bis((3S)-3-MethylMorpholin-4-yl)pyrido[;5-[2,4-Bis[(3S)-3-Methyl-4-Morpholinyl]pyrido[2,3-d]pyriMidin-7-yl]-2-MethoxybenzeneMethanol;CCG 168;AZD8055,AZD-8055
37 prices
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Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 20mg
  • 2x25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1166-M050
  • Product descriptionAZD-8055 ≥95%
  • Packaging50mg
  • Price$346
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX7420
  • Product descriptionAZD8055
  • Packaging50mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA224432
  • Product description(5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+%
  • Packaging5mg
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA224432
  • Product description(5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+%
  • Packaging10mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA224432
  • Product description(5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+%
  • Packaging50mg
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA224432
  • Product description(5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+%
  • Packaging100mg
  • Price$188
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA224432
  • Product description(5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+%
  • Packaging250mg
  • Price$371
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA224432
  • Product description(5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+%
  • Packaging1g
  • Price$927
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000924
  • Product descriptionAZD-8055 95.00%
  • Packaging10MG
  • Price$779.63
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000924
  • Product descriptionAZD-8055 95.00%
  • Packaging100MG
  • Price$2194.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8214
  • Product descriptionAZD8055
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60002
  • Product descriptionAZD8055 ≥98%
  • Packaging20mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1561
  • Product descriptionAZD8055 99%
  • Packaging2x25mg
  • Price$396
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546257
  • Product descriptionAZD8055 >98%
  • Packaging50mg
  • Price$314.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546257
  • Product descriptionAZD8055 >98%
  • Packaging10mg
  • Price$146.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154690
  • Product descriptionAZD-8055 >98%
  • Packaging100mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1166-M050 AZD-8055 ≥95% 50mg $346 2021-12-16 Buy
AK Scientific X7420 AZD8055 50mg $132 2021-12-16 Buy
Ambeed A224432 (5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+% 5mg $26 2021-12-16 Buy
Ambeed A224432 (5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+% 10mg $45 2021-12-16 Buy
Ambeed A224432 (5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+% 50mg $98 2021-12-16 Buy
Ambeed A224432 (5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+% 100mg $188 2021-12-16 Buy
Ambeed A224432 (5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+% 250mg $371 2021-12-16 Buy
Ambeed A224432 (5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 98+% 1g $927 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000924 AZD-8055 95.00% 10MG $779.63 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000924 AZD-8055 95.00% 100MG $2194.5 2021-12-16 Buy
ApexBio Technology A8214 AZD8055 10mg $50 2021-12-16 Buy
Arctom CFN60002 AZD8055 ≥98% 20mg $198 2021-12-16 Buy
Axon Medchem Axon1561 AZD8055 99% 2x25mg $396 2021-12-16 Buy
Biorbyt Ltd orb546257 AZD8055 >98% 50mg $314.5 2021-12-16 Buy
Biorbyt Ltd orb546257 AZD8055 >98% 10mg $146.2 2021-12-16 Buy
Biorbyt Ltd orb154690 AZD-8055 >98% 100mg $615.4 2021-12-16 Buy

Properties

Melting point :204 - 207°C
Boiling point :694.3±65.0 °C(Predicted)
Density :1.248
storage temp. :-20°C
solubility :Soluble in DMSO (up to 30 mg/ml)
form :Yellow powder.
pka :14.20±0.10(Predicted)
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

AZD 8055 is a potent, selective ATP-competitive inhibitor of mTOR, exhibiting an IC50 value of 0.8 nM. It is ~1,000-fold selective for mTOR over all PI3K isoforms and exhibits no activity against a panel of 260 kinases at concentrations up to 10 μM. AZD 8055 inhibits proliferation of A549 and H838 cells with IC50 values of 53 and 20 nM, respectively. It inhibits growth of a variety of human tumor xenografts by at least 65% in mice at daily oral doses of 20 mg/kg.

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