MK-2206 2HCl
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- $10 - $5132
- Product name: MK-2206 2HCl
- CAS: 1032350-13-2
- MF: C25H22ClN5O
- MW: 443.94
- EINECS:
- MDL Number:MFCD14584463
- Synonyms:MK-2206 Dihydrochloride;8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride;8-[4-(1-AMinocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one Hydrochloride;8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one;8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride MK-2206;MK-2206 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride;MK 2206 (hydrochloride);MK-2206 dihydrochloride, >=98%
46 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
- Usbiological
Package
- 500ug
- 1mg
- 1unit
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1g
- 1000mg
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1162-M100
- Product descriptionMK-2206dihydrochloride ≥95%
- Packaging100mg
- Price$1010
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2181AH
- Product descriptionMK-2206dihydrochloride
- Packaging5mg
- Price$126
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2181AH
- Product descriptionMK-2206dihydrochloride
- Packaging25mg
- Price$193
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2181AH
- Product descriptionMK-2206dihydrochloride
- Packaging1g
- Price$1369
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA145592
- Product description8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-onedihydrochloride 98+%
- Packaging1mg
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA145592
- Product description8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-onedihydrochloride 98+%
- Packaging5mg
- Price$22
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA145592
- Product description8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-onedihydrochloride 98+%
- Packaging10mg
- Price$33
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA145592
- Product description8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-onedihydrochloride 98+%
- Packaging50mg
- Price$83
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA145592
- Product description8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-onedihydrochloride 98+%
- Packaging100mg
- Price$124
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA145592
- Product description8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-onedihydrochloride 98+%
- Packaging250mg
- Price$211
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA145592
- Product description8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-onedihydrochloride 98+%
- Packaging1g
- Price$533
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010054
- Product descriptionMK-2206 DIHYDROCHLORIDE SALT 99.00%
- Packaging1MG
- Price$191.1
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010054
- Product descriptionMK-2206 DIHYDROCHLORIDE SALT 99.00%
- Packaging5MG
- Price$816.75
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010054
- Product descriptionMK-2206 DIHYDROCHLORIDE SALT 99.00%
- Packaging50MG
- Price$2194.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3010
- Product descriptionMK-2206dihydrochloride
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0108
- Product descriptionMK-2206 dihydrochloride
- Packaging10mg
- Price$129
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-1162-M100 | MK-2206dihydrochloride ≥95% | 100mg | $1010 | 2021-12-16 | Buy |
| AK Scientific | 2181AH | MK-2206dihydrochloride | 5mg | $126 | 2021-12-16 | Buy |
| AK Scientific | 2181AH | MK-2206dihydrochloride | 25mg | $193 | 2021-12-16 | Buy |
| AK Scientific | 2181AH | MK-2206dihydrochloride | 1g | $1369 | 2021-12-16 | Buy |
| Ambeed | A145592 | 8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-onedihydrochloride 98+% | 1mg | $10 | 2021-12-16 | Buy |
| Ambeed | A145592 | 8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-onedihydrochloride 98+% | 5mg | $22 | 2021-12-16 | Buy |
| Ambeed | A145592 | 8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-onedihydrochloride 98+% | 10mg | $33 | 2021-12-16 | Buy |
| Ambeed | A145592 | 8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-onedihydrochloride 98+% | 50mg | $83 | 2021-12-16 | Buy |
| Ambeed | A145592 | 8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-onedihydrochloride 98+% | 100mg | $124 | 2021-12-16 | Buy |
| Ambeed | A145592 | 8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-onedihydrochloride 98+% | 250mg | $211 | 2021-12-16 | Buy |
| Ambeed | A145592 | 8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-onedihydrochloride 98+% | 1g | $533 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010054 | MK-2206 DIHYDROCHLORIDE SALT 99.00% | 1MG | $191.1 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010054 | MK-2206 DIHYDROCHLORIDE SALT 99.00% | 5MG | $816.75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010054 | MK-2206 DIHYDROCHLORIDE SALT 99.00% | 50MG | $2194.5 | 2021-12-16 | Buy |
| ApexBio Technology | A3010 | MK-2206dihydrochloride | 1unit | $28 | 2021-12-16 | Buy |
| Apolloscientific | BISN0108 | MK-2206 dihydrochloride | 10mg | $129 | 2021-12-16 | Buy |
Properties
Melting point :>255°C (dec.)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 10 mg/ml with warming)
form :Yellow powder.
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
storage temp. :-20°C
solubility :Soluble in DMSO (up to 10 mg/ml with warming)
form :Yellow powder.
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKBα, β, γ) modulate cell proliferation, metabolism, and survival as well as angiogenesis. MK-2206 is an orally active, allosteric Akt inhibitor that is equally potent toward purified human recombinant Akt1 and Akt2 (IC50s = 5 and 12 nM, respectively) and approximately 5-fold less potent against human Akt3 (IC50 = 65 nM). In combination with other anticancer agents including topoisomerase inhibitors, antimetabolites, antimicrotubule agents, DNA cross-linkers or growth factor inhibitors, MK-2206 has been shown to synergistically inhibit cell proliferation of human cancer cell lines. At 5 μM, MK-2206 significantly enhances apoptosis in hematopoietic cells treated with chemotherapeutics.Related product price
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