6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-1-CARBOXAMIDE
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- $32 - $1949.9
- Product name: 6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-1-CARBOXAMIDE
- CAS: 49843-98-3
- MF: C13H13ClN2O
- MW: 248.71
- EINECS:
- MDL Number:MFCD03009471
- Synonyms:6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-1-CARBOXAMIDE;6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-1-CARBOXAMIDE, >95%;(S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide;SEN0014196;6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide EX-527 Selisistat;EX 527, >=98%;EX 527 (Selisistat);Selisistat 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxaMide
47 prices
Selected condition：
Brand
- Abosyn
- AK Scientific
- Alfa Aesar
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 20mg
- 100mg
- 250mg
- 1g
- 1000mg
- 10mM(in 1mL DMSO)
- 1MG
- 5MG
- 10mg
- 25MG
- 50mg
- ManufacturerAbosyn
- Product number61-11391
- Product description6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide 95-98%
- Packaging1g
- Price$882
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7534
- Product descriptionEX 527
- Packaging1g
- Price$1665
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64753
- Product descriptionEX 527
- Packaging10mg
- Price$126.65
- Updated2024-03-01
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0003768
- Product descriptionEX 527 95.00%
- Packaging1MG
- Price$565.14
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0003768
- Product descriptionEX 527 95.00%
- Packaging5MG
- Price$663.2
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0003768
- Product descriptionEX 527 95.00%
- Packaging25MG
- Price$885.31
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4181
- Product descriptionEX527(SEN0014196)
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4181
- Product descriptionEX527(SEN0014196)
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4181
- Product descriptionEX527(SEN0014196)
- Packaging25mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0099
- Product descriptionEX 527
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0099
- Product descriptionEX 527
- Packaging10mg
- Price$124
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0099
- Product descriptionEX 527
- Packaging25mg
- Price$153
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS045971
- Product description6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide ≥98%
- Packaging5mg
- Price$32
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS045971
- Product description6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide ≥98%
- Packaging10mg
- Price$41
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS045971
- Product description6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide ≥98%
- Packaging25mg
- Price$79
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60035
- Product descriptionSelisistat(EX527) ≥98%
- Packaging20mg
- Price$168
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Abosyn | 61-11391 | 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide 95-98% | 1g | $882 | 2021-12-16 | Buy |
| AK Scientific | X7534 | EX 527 | 1g | $1665 | 2021-12-16 | Buy |
| Alfa Aesar | J64753 | EX 527 | 10mg | $126.65 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | INB0003768 | EX 527 95.00% | 1MG | $565.14 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0003768 | EX 527 95.00% | 5MG | $663.2 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0003768 | EX 527 95.00% | 25MG | $885.31 | 2021-12-16 | Buy |
| ApexBio Technology | A4181 | EX527(SEN0014196) | 10mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A4181 | EX527(SEN0014196) | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A4181 | EX527(SEN0014196) | 25mg | $110 | 2021-12-16 | Buy |
| Apolloscientific | BISN0099 | EX 527 | 5mg | $80 | 2021-12-16 | Buy |
| Apolloscientific | BISN0099 | EX 527 | 10mg | $124 | 2021-12-16 | Buy |
| Apolloscientific | BISN0099 | EX 527 | 25mg | $153 | 2021-12-16 | Buy |
| Arctom | AS045971 | 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide ≥98% | 5mg | $32 | 2021-12-16 | Buy |
| Arctom | AS045971 | 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide ≥98% | 10mg | $41 | 2021-12-16 | Buy |
| Arctom | AS045971 | 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide ≥98% | 25mg | $79 | 2021-12-16 | Buy |
| Arctom | CFN60035 | Selisistat(EX527) ≥98% | 20mg | $168 | 2021-12-16 | Buy |
Properties
Melting point :179.0 to 183.0 °C
Boiling point :531.7±38.0 °C(Predicted)
Density :1.388
storage temp. :2-8°C
solubility :Soluble in dimethyl sulfoxide, ethanol and dimethyl formamide.
form :powder
pka :16.12±0.40(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
Boiling point :531.7±38.0 °C(Predicted)
Density :1.388
storage temp. :2-8°C
solubility :Soluble in dimethyl sulfoxide, ethanol and dimethyl formamide.
form :powder
pka :16.12±0.40(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | ||||||||||||||||||||||||||||
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Description
EX-527 is a potent and selective sirtuin 1 (SIRT1) inhibitor (IC50 38 nM) identified from a high throughput screen. EX-527 is more selective (200-500-fold) for SIRT1 than for SIRT2 or SIRT3 and has been shown to be a potent SIRT6 inhibitor using H3K56 deacetylation site based substrate. EX-527 does not inhibit class I/II HDAC activity at concentrations up to 100uM. Enhances p53 acetylation in response to DNA damaging agents. EX-527 is racemic; the active isomer (EX-243) gives similar results and potency whereas the other isomer (designated EX-242) is inactive.More related product prices
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