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ChemicalBook >> CAS DataBase List >> 9-Cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8H-purin-8-one

9-Cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8H-purin-8-one

9-Cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8H-purin-8-one price.
  • $5 - $2597
  • Product name: 9-Cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8H-purin-8-one
  • CAS: 1124329-14-1
  • MF: C24H32N6O3
  • MW: 452.55
  • EINECS:
  • MDL Number:MFCD18384959
  • Synonyms:9-Cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8H-purin-8-one;AZ 3146;9-cyclopentyl-2-(2-Methoxy-4-(1-Methylpiperidin-4-yloxy)phenylaMino)-7-Methyl-7H-purin-8(9H)-one;9-Cyclopentyl-7,9-dihydro-2-[[2-methoxy-4-[(1-methyl-4-piperidinyl)oxy]phenyl]amino]-7-methyl-8H-purin-8-one;9-Cyclopentyl-7,9-dihydro-2-[[2-methoxy-4-[(1-methyl-4-piperidinyl)oxy]phenyl]amino]-7-methyl-8H-purin-8-one AZ3146;9-Cyclopentyl-2-((2-methoxy-4-((1-methylpiperidin-4-yl)oxy)phenyl)amino)-7-methyl-7H-purin-8(9;AZ 3146; AZ-3146;CS-511
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  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Ark Pharm
  • Axon Medchem
  • Biorbyt Ltd
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  • Cayman Chemical
  • Chemenu
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  • ManufacturerAK Scientific
  • Product numberSYN5485
  • Product descriptionAZ3146
  • Packaging100mg
  • Price$810
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0290
  • Product descriptionAZ3146
  • Packaging1g
  • Price$2597
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA174095
  • Product description9-Cyclopentyl-2-((2-methoxy-4-((1-methylpiperidin-4-yl)oxy)phenyl)amino)-7-methyl-7H-purin-8(9H)-one 98+%
  • Packaging1mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA174095
  • Product description9-Cyclopentyl-2-((2-methoxy-4-((1-methylpiperidin-4-yl)oxy)phenyl)amino)-7-methyl-7H-purin-8(9H)-one 98+%
  • Packaging5mg
  • Price$7
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA174095
  • Product description9-Cyclopentyl-2-((2-methoxy-4-((1-methylpiperidin-4-yl)oxy)phenyl)amino)-7-methyl-7H-purin-8(9H)-one 98+%
  • Packaging10mg
  • Price$9
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA174095
  • Product description9-Cyclopentyl-2-((2-methoxy-4-((1-methylpiperidin-4-yl)oxy)phenyl)amino)-7-methyl-7H-purin-8(9H)-one 98+%
  • Packaging50mg
  • Price$15
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA174095
  • Product description9-Cyclopentyl-2-((2-methoxy-4-((1-methylpiperidin-4-yl)oxy)phenyl)amino)-7-methyl-7H-purin-8(9H)-one 98+%
  • Packaging100mg
  • Price$26
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA174095
  • Product description9-Cyclopentyl-2-((2-methoxy-4-((1-methylpiperidin-4-yl)oxy)phenyl)amino)-7-methyl-7H-purin-8(9H)-one 98+%
  • Packaging250mg
  • Price$48
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000889
  • Product descriptionAZ-3146 95.00%
  • Packaging5MG
  • Price$249.7
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8372
  • Product descriptionAZ3146
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8372
  • Product descriptionAZ3146
  • Packaging10mM(in 1mL Ethanol)
  • Price$94
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8372
  • Product descriptionAZ3146
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8372
  • Product descriptionAZ3146
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000532853
  • Product descriptionAZ3146 98+%
  • Packaging5mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000532853
  • Product descriptionAZ3146 98+%
  • Packaging10mg
  • Price$161
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000532853
  • Product descriptionAZ3146 98+%
  • Packaging50mg
  • Price$504
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5485 AZ3146 100mg $810 2021-12-16 Buy
AK Scientific Y0290 AZ3146 1g $2597 2021-12-16 Buy
Ambeed A174095 9-Cyclopentyl-2-((2-methoxy-4-((1-methylpiperidin-4-yl)oxy)phenyl)amino)-7-methyl-7H-purin-8(9H)-one 98+% 1mg $5 2021-12-16 Buy
Ambeed A174095 9-Cyclopentyl-2-((2-methoxy-4-((1-methylpiperidin-4-yl)oxy)phenyl)amino)-7-methyl-7H-purin-8(9H)-one 98+% 5mg $7 2021-12-16 Buy
Ambeed A174095 9-Cyclopentyl-2-((2-methoxy-4-((1-methylpiperidin-4-yl)oxy)phenyl)amino)-7-methyl-7H-purin-8(9H)-one 98+% 10mg $9 2021-12-16 Buy
Ambeed A174095 9-Cyclopentyl-2-((2-methoxy-4-((1-methylpiperidin-4-yl)oxy)phenyl)amino)-7-methyl-7H-purin-8(9H)-one 98+% 50mg $15 2021-12-16 Buy
Ambeed A174095 9-Cyclopentyl-2-((2-methoxy-4-((1-methylpiperidin-4-yl)oxy)phenyl)amino)-7-methyl-7H-purin-8(9H)-one 98+% 100mg $26 2021-12-16 Buy
Ambeed A174095 9-Cyclopentyl-2-((2-methoxy-4-((1-methylpiperidin-4-yl)oxy)phenyl)amino)-7-methyl-7H-purin-8(9H)-one 98+% 250mg $48 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000889 AZ-3146 95.00% 5MG $249.7 2021-12-16 Buy
ApexBio Technology A8372 AZ3146 10mg $85 2021-12-16 Buy
ApexBio Technology A8372 AZ3146 10mM(in 1mL Ethanol) $94 2021-12-16 Buy
ApexBio Technology A8372 AZ3146 50mg $250 2021-12-16 Buy
ApexBio Technology A8372 AZ3146 100mg $450 2021-12-16 Buy
Ark Pharm P000532853 AZ3146 98+% 5mg $95 2021-12-16 Buy
Ark Pharm P000532853 AZ3146 98+% 10mg $161 2021-12-16 Buy
Ark Pharm P000532853 AZ3146 98+% 50mg $504 2021-12-16 Buy

Properties

Boiling point :621.0±65.0 °C(Predicted)
Density :1.279
storage temp. :Store at +4°C
solubility :Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to at least 25 mg/ml)
form :solid
pka :8.29±0.10(Predicted)
color :Off-white
Stability :Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

AZ3146 (1124329-14-1) is a potent (IC50?= 35 nM) and selective monopolar spindle 1 (Mps1/TTK) kinase inhibitor.1?Mps1 has an essential role in the spindle assembly checkpoint, an inhibitory network that restrains anaphase until all kinetochores are stably attached to spindle microtubules during mitosis. AZ3146 decreased hepatocellular carcinoma growth in vitro (SMMC-7721 and BEL-7404 cells).2

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