成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

ChemicalBook--->CAS DataBase List--->1124329-14-1

1124329-14-1

1124329-14-1 Structure

1124329-14-1 Structure
IdentificationBack Directory
[Name]

9-Cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8H-purin-8-one
[CAS]

1124329-14-1
[Synonyms]

CS-511
AZ 3146
1124329-14-1
AZ 3146; AZ-3146
AZ3146 >=98% (HPLC)
AZ3146; AZ 3146; AZ-3146
AZ3146 Mps1 Inhibitor III AZ-3146
9-Cyclopentyl-2-({2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]phenyl}amino)-7-methylpurin-8-one
9-Cyclopentyl-2-((2-methoxy-4-((1-methylpiperidin-4-yl)oxy)phenyl)amino)-7-methyl-7H-purin-8(9
9-cyclopentyl-2-(2-Methoxy-4-(1-Methylpiperidin-4-yloxy)phenylaMino)-7-Methyl-7H-purin-8(9H)-one
9-Cyclopentyl-7,9-dihydro-2-[[2-methoxy-4-[(1-methyl-4-piperidinyl)oxy]phenyl]amino]-7-methyl-8H-purin-8-one
9-Cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8H-purin-8-one
8H-Purin-8-one, 9-cyclopentyl-7,9-dihydro-2-[[2-methoxy-4-[(1-methyl-4-piperidinyl)oxy]phenyl]amino]-7-methyl-
9-Cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8H-purin-8-one USP/EP/BP
9-Cyclopentyl-7,9-dihydro-2-[[2-methoxy-4-[(1-methyl-4-piperidinyl)oxy]phenyl]amino]-7-methyl-8H-purin-8-one AZ3146
[Molecular Formula]

C24H32N6O3
[MDL Number]

MFCD18384959
[MOL File]

1124329-14-1.mol
[Molecular Weight]

453
Chemical PropertiesBack Directory
[Boiling point ]

621.0±65.0 °C(Predicted)
[density ]

1.279
[storage temp. ]

Store at +4°C
[solubility ]

Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to at least 25 mg/ml)
[form ]

solid
[pka]

8.29±0.10(Predicted)
[color ]

Off-white
[Stability:]

Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Hazard InformationBack Directory
[Description]

AZ3146 (1124329-14-1) is a potent (IC50?= 35 nM) and selective monopolar spindle 1 (Mps1/TTK) kinase inhibitor.1?Mps1 has an essential role in the spindle assembly checkpoint, an inhibitory network that restrains anaphase until all kinetochores are stably attached to spindle microtubules during mitosis. AZ3146 decreased hepatocellular carcinoma growth in vitro (SMMC-7721 and BEL-7404 cells).2
[Uses]

AZ 3146 is a protein kinase Mps1 inhibitor.
[Enzyme inhibitor]

This selective inhibitor (FW = 452.55 g/mL; CAS 1124329-14-1; Solubility: 28 mg/mL DMSO; <1 mg/mL Water), also known as 9- cyclopentyl-2- (2-methoxy-4- (1-methylpiperidin-4-yloxy) phenylamino) -7- methyl-7H-purin-8 (9H) -one, inhibits MPS1 protein kinases (IC50 = 35 nM), which are found widely, but not ubiquitously, in eukaryotes and regulate kinetochore in both the chromosome attachment and the spindle checkpoints. MPS1 kinases also regulate centrosome function.
[storage]

Store at +4°C
[References]

1) Hewitt?et al. (2010)?Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex; J. Cell Biol.?190?25 2) Liu?et al.?(2015)?TTK activates Akt and promotes proliferation and migration of hepatocellular carcinoma cells; Oncotarget?6?34309
1124329-14-1 suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Website: www.atkchemical.com
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 18871490254
Website: www.hubeijusheng.com
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +8613203830695 , +8613203830695
Website: www.coreychem.com/
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250 , +86-15129568250
Website: https://www.dideu.com
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471 , +1-2135480471
Website: https://www.sarms4muscle.com
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105 , +1-13798911105
Website: https://www.invivochem.com/
Company Name: LEAP CHEM CO., LTD.
Tel: +86-852-30606658
Website: www.leapchem.com
Company Name: ShenZhen Trendseen Biological Technology Co.,Ltd.
Tel: 13417589054 , 13417589054
Website: m.is0513.com/ShowSupplierProductsList1962465/0.htm
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Website: www.aladdinsci.com/
Company Name: Amadis Chemical Company Limited
Tel: 571-89925085
Website: http://www.amadischem.com
Company Name: Shanghai Boyle Chemical Co., Ltd.  
Tel:
Website: www.boylechem.com
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801 18930552037
Website: http://m.is0513.com/ShowSupplierProductsList13285/0.htm
Company Name: WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.  
Tel: 17702719238 17702719238
Website: http://www.sun-shinechem.com/
Company Name: Jinan Trio PharmaTech Co., Ltd.  
Tel: +86 (531) 88811783
Website: www.trio-pharmatech.com
Company Name: Dalian Meilun Biotech Co., Ltd.  
Tel: 0411-62910999 13889544652
Website: http://www.meilune.com/
Company Name: Hangzhou Sage Chemical Co., Ltd.  
Tel: +86057186818502 13588463833
Website: www.sagechem.com
Company Name: Chengdu NoVi Biotechnology Co., Ltd.  
Tel: 028-81458053
Website: m.is0513.com/ShowSupplierProductsList15717/0.htm
Tags:1124329-14-1 Related Product Information
923978-27-2 1420477-60-6 57226-68-3 955365-80-7 1257044-40-8 1246529-32-7 1255517-76-0 1088965-37-0 936091-26-8