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ChemicalBook >> CAS DataBase List >> PF-4708671

PF-4708671

PF-4708671 price.
  • $15 - $2691.1
  • Product name: PF-4708671
  • CAS: 1255517-76-0
  • MF: C19H21F3N6
  • MW: 390.41
  • EINECS:
  • MDL Number:MFCD18086922
  • Synonyms:2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzo[d]imidazole;PF 4708671;PF4708671/PF-4708671;2-[[4-(5-ethyl-4-pyriMidinyl)-1-piperazinyl]Methyl]-6-(trifluoroMethyl)-1H-benziMidazole;PF-04708671;1H-Benzimidazole, 2-[[4-(5-ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-;2-[[4-(5-Ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-1H-benzimidazole PF-4708671;2-[[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-6-(trifluoromethyl)-1H-benzimidazole
35 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Apolloscientific
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 25
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 1000mg
  • ManufacturerAK Scientific
  • Product number2644AH
  • Product description2-((4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-6-(trifluoromethyl)-1H-benzo[d]imidazole
  • Packaging5mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130606
  • Product descriptionPF-4708671 98+%
  • Packaging1mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130606
  • Product descriptionPF-4708671 98+%
  • Packaging5mg
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130606
  • Product descriptionPF-4708671 98+%
  • Packaging10mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130606
  • Product descriptionPF-4708671 98+%
  • Packaging50mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130606
  • Product descriptionPF-4708671 98+%
  • Packaging100mg
  • Price$212
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130606
  • Product descriptionPF-4708671 98+%
  • Packaging250mg
  • Price$318
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2228
  • Product descriptionPF-4708671
  • Packaging25mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0176
  • Product descriptionPF-4708671
  • Packaging50mg
  • Price$276
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBISN0176
  • Product descriptionPF-4708671
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBISN0176
  • Product descriptionPF-4708671
  • Packaging5mg
  • Price$58
  • Updated2021-12-16
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  • ManufacturerAxon Medchem
  • Product numberAxon1602
  • Product descriptionPF4708671-PF04708671 99%
  • Packaging10mg
  • Price$121
  • Updated2021-12-16
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  • ManufacturerAxon Medchem
  • Product numberAxon1602
  • Product descriptionPF4708671-PF04708671 99%
  • Packaging50mg
  • Price$418
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181084
  • Product descriptionPF-4708671 >98%
  • Packaging100mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181084
  • Product descriptionPF-4708671 >98%
  • Packaging250mg
  • Price$1356.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181084
  • Product descriptionPF-4708671 >98%
  • Packaging1000mg
  • Price$2691.1
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2644AH 2-((4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-6-(trifluoromethyl)-1H-benzo[d]imidazole 5mg $116 2021-12-16 Buy
Ambeed A130606 PF-4708671 98+% 1mg $15 2021-12-16 Buy
Ambeed A130606 PF-4708671 98+% 5mg $37 2021-12-16 Buy
Ambeed A130606 PF-4708671 98+% 10mg $55 2021-12-16 Buy
Ambeed A130606 PF-4708671 98+% 50mg $145 2021-12-16 Buy
Ambeed A130606 PF-4708671 98+% 100mg $212 2021-12-16 Buy
Ambeed A130606 PF-4708671 98+% 250mg $318 2021-12-16 Buy
ApexBio Technology B2228 PF-4708671 25mg $110 2021-12-16 Buy
Apolloscientific BISN0176 PF-4708671 50mg $276 2021-12-16 Buy
Apolloscientific BISN0176 PF-4708671 10mg $95 2021-12-16 Buy
Apolloscientific BISN0176 PF-4708671 5mg $58 2021-12-16 Buy
Axon Medchem Axon1602 PF4708671-PF04708671 99% 10mg $121 2021-12-16 Buy
Axon Medchem Axon1602 PF4708671-PF04708671 99% 50mg $418 2021-12-16 Buy
Biorbyt Ltd orb181084 PF-4708671 >98% 100mg $690.2 2021-12-16 Buy
Biorbyt Ltd orb181084 PF-4708671 >98% 250mg $1356.6 2021-12-16 Buy
Biorbyt Ltd orb181084 PF-4708671 >98% 1000mg $2691.1 2021-12-16 Buy

Properties

Boiling point :572.8±50.0 °C(Predicted)
Density :1.348±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥20mg/mL
form :powder
pka :10.20±0.10(Predicted)
color :off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

P70 ribosomal S6 kinase (S6K1) is a serine/threonine kinase which is activated by insulin and growth factors through PI3K and mTORC1 signaling pathways. PF-04708671 is a specific, cell-permeable inhibitor of S6K1 (IC50 = 160 nM). It does not inhibit S6K2, MSK, or RSK, or many other unrelated kinases, under conditions in which it inhibits S6K1 activity. It is useful in evaluating the role of S6K1 and, indirectly, mTORC1, in cell signaling.

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