Rabbit Anti-VEGFA Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:VEGFA
IR:Immunogen Range:301-393/393
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7422
Swiss Prot:P15692
Source:KLH conjugated synthetic peptide derived from human VEGFA:301-393/393
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Sheep
Guinea Pig
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： VEGFA;Vascuoar endothelial;VEGF A;MGC70609;MVCD1;VEGF;VPF;VEGFA_HUMAN;
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