127-31-1
中文名稱
氟氫可的松
英文名稱
Fludrocortisone
CAS
127-31-1
EINECS 編號
204-833-2
分子式
C21H27FO5
MDL 編號
MFCD00083333
分子量
378.43
MOL 文件
127-31-1.mol
更新日期
2024/07/22 17:33:48
127-31-1 結(jié)構(gòu)式
基本信息
中文別名
氟氫可的松 英文別名
4-PREGNEN-9-ALPHA-FLUORO-11-BETA, 17,21-TRIOL-3,20-DIONE4-PREGNEN-9ALPHA-FLUORO-11BETA, 17ALPHA, 21-TRIOL-3, 20-DIONE
4-PREGNENE-9-ALPHA-FLUORO-11-BETA,17-ALPHA,21-TRIOL-3,20-DIONE
9a-fluoro-11b,17a,21-trihydroxy-4-pregnene-3,20-dione
9a-fluoro-17-hydroxycorticosterone
9-ALPHA-FLUORO-11-BETA,17-ALPHA,21-TRIHYDROXY-4-PREGNENE-3,20-DIONE
9-ALPHA-FLUOROHYDROCORTISONE
9-FLUOROCORTISOL
FLUDROCORTISONE
FLUOROCORTISONE
17,21-trihydroxy-20-dion(11beta)-pregn-4-ene-9-fluoro-11
9alpha-fludrocortisone
9-alpha-fluoro-17-hydroxycorticosterone
9alpha-fluoro-17-hydroxycorticosterone
9-alpha-fluorocortisol
9alpha-fluorocortisol
9-fluoro-11-beta,17,21-trihydroxy-pregn-4-ene-20-dione
9-fluoro-11beta,17,21-trihydroxy-pregn-4-ene-20-dione
9-fluoro-11-beta,17,21-trihydroxypregn-4-ene-3,20-dione
9-fluorohydrocortisone
所屬類別
原料藥：腎上腺皮質(zhì)激素類藥物理化學(xué)性質(zhì)
熔點208-212°C
比旋光度D23 +139° (c = 0.55 in 95% ethanol)
沸點564.7±50.0 °C(Predicted)
密度1.1176 (estimate)
儲存條件Refrigerator
溶解度可溶于DMSO（輕微）、乙醇（輕微、加熱）、甲醇（輕微、超聲處理）
酸度系數(shù)(pKa)12.11±0.70(Predicted)
形態(tài)固體
顏色白色至灰白色
水溶解性111mg/L(25 ºC)
CAS 數(shù)據(jù)庫127-31-1(CAS DataBase Reference)
EPA化學(xué)物質(zhì)信息Hydrocortisone-9.alpha.-fluoro (127-31-1)
安全數(shù)據(jù)
警示詞警告
危險性描述H302-H312-H361-H332
危險品標志Xn
危險類別碼63
安全說明22-26-36
毒害物質(zhì)數(shù)據(jù)127-31-1(Hazardous Substances Data)
毒性LD50 intraperitoneal in mouse: 170mg/kg