Methyl 3-O-methylgallate (M3OMG) 具有抗氧化作用,能保護(hù)神經(jīng)元細(xì)胞免受氧化損傷。
Methyl 3-O-methylgallate (M3OMG; 10 and 20 mg/kg, i.p., ) treatment mitigated the NaF-induced oxidative stress through normalization of the level of TBARS, reduced levels of glutathione and by the restoration of the diminished antioxidant enzyme activities.
Animal Model:
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Fifty male Wistar rats (8-12 , 7-days old, 200-250 g).
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Dosage:
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10 and 20 mg/kg.
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Administration:
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I.P. for 1 week.
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Result:
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Mitigated the NaF-induced oxidative stress through normalization of the level of TBARS, reduced levels of glutathione and by the restoration of the diminished antioxidant enzyme activities.
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用途
聯(lián)苯雙酯的中間體。
生產(chǎn)方法
用沒食子酸以甲醇在硫酸參與下酯化,生成3,4,5-三羥基苯甲酸甲酯,然后以硫酸二甲酯醚化制得該品。