N,N'-二乙酰-L-胱氨酸
| 中文名稱 | N,N'-二乙酰-L-胱氨酸 |
|---|---|
| 中文同義詞 | N,N'-二乙酰-L-胱氨酸;N,N'-二乙酰基-L-胱氨酸;乙酰半胱氨酸EP雜質(zhì)C;雙乙?；?L-胱氨酸;N-乙酰半胱氨酸雜質(zhì)C(EP) 標(biāo)準(zhǔn)品;N,N'-二乙酰胱氨酸;乙酰半胱氨酸雜質(zhì)01;S - [2 - (乙酰氨基)乙基] 羧酸 ;N,N'-二乙酰-L-胱氨酸 |
| 英文名稱 | (AC-CYS-OH)2 |
| 英文同義詞 | (Ac-L-Cys-OH)2;(Ac-L-Cys-OH)2(Disulfide bond)≥ 99.5% (GC, Chiral purity);3,3'-Dithiobis[(R)-2-acetylaminopropionic acid];NSC 203780;L-Cystine, N,N'-diacetyl-;Acetylcysteine EP IMpurity C;N-ACETYL CYSTINE;N-ALPHA-ACETYL-L-CYSTINE |
| CAS號(hào) | 5545-17-5 |
| 分子式 | C10H16N2O6S2 |
| 分子量 | 324.37 |
| EINECS號(hào) | 226-911-5 |
| 相關(guān)類別 | 對(duì)照品-雜質(zhì)對(duì)照品;雜質(zhì)對(duì)照品;有機(jī)化工原料;Pharmaceuticals;Amino Acids & Derivatives;Intermediates & Fine Chemicals |
| Mol文件 | 5545-17-5.mol |
| 結(jié)構(gòu)式 |  |
N,N'-二乙酰-L-胱氨酸 性質(zhì)
| 熔點(diǎn) | 55-72°C |
|---|---|
| 儲(chǔ)存條件 | Sealed in dry,2-8°C |
| 溶解度 | 甲醇（微溶）、水（微溶） |
| 形態(tài) | 固體 |
| 顏色 | 白色至淺米色 |
| 穩(wěn)定性 | 濕氣敏感 |
| InChIKey | YTPQSLLEROSACP-YUMQZZPRSA-N |
| CAS 數(shù)據(jù)庫(kù) | 5545-17-5 |
N,N'-diacetyl-L-cystine (DiNAC) 是一種具有免疫調(diào)節(jié)特性的 N-乙?；腚装彼岬亩蚨垠w。N,N'-diacetyl-L-cystine 是嚙齒類動(dòng)物中接觸敏感/遲發(fā)型超敏反應(yīng)的有效口服活性調(diào)節(jié)劑。N,N'-diacetyl-L-cystine 在高脂血癥兔 (WHHL) 中也具有抗動(dòng)脈粥樣硬化的作用。
Immunomodulator
N,N'-Diacetyl-L-cystine (DiNAC; 0-973.11 μg/kg; oral administration; daily; for 12 weeks; WHHL rabbits) treatment reduces by 50% thoracic aorta atherosclerosis, without affecting plasma lipid levels.
| Animal Model: | Male heritable hyperlipidemic rabbit (WHHL) rabbits (10-22 weeks) |
| Dosage: | 0 μg/kg, 9.73 μg/kg, or 973.11 μg/kg |
| Administration: | Oral administration; daily; for 12 weeks |
| Result: | Reduced by 50% thoracic aorta atherosclerosis, without affecting plasma lipid levels. |
安全信息
| 海關(guān)編碼 | 29225090 |
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