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ChemicalBook >> CAS DataBase List >> Mitotan

Mitotan

Mitotan price.
  • $20 - $1504.5
  • Product name: Mitotan
  • CAS: 53-19-0
  • MF: C14H10Cl4
  • MW: 320.04
  • EINECS:200-166-6
  • MDL Number:MFCD00000850
  • Synonyms:2,4’-dichlorophenyldichlorethane ;2,4'-Dichlorophenyldichlorethane;Benzene, 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-;Ethane, 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)-;Ethane, 2-(o-chlorophenyl)-2-(p-chlorophenyl)-1,1-dichloro-;ethane,2,2-dichloro-1-(2-chlorophenyl)-1-(4-chlorophenyl)- ;Khlodithan;NCI-C04933
33 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • Chem-Impex
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 2g
  • 2.5G
  • 5g
  • 10mM(in 1mL DMSO)
  • 25g
  • 50g
  • ManufacturerAHH
  • Product numberMT-19139
  • Product descriptionMitotan 99%
  • Packaging50g
  • Price$325
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberC599
  • Product description1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane
  • Packaging250mg
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA817688
  • Product description1-Chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)benzene 99+%
  • Packaging1g
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA817688
  • Product description1-Chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)benzene 99+%
  • Packaging5g
  • Price$64
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA817688
  • Product description1-Chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)benzene 99+%
  • Packaging25g
  • Price$212
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003407
  • Product descriptionMITOTANE 95.00%
  • Packaging1G
  • Price$619.7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003407
  • Product descriptionMITOTANE 95.00%
  • Packaging2.5G
  • Price$796.77
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003407
  • Product descriptionMITOTANE 95.00%
  • Packaging5G
  • Price$912.29
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8475
  • Product descriptionMitotane(Lsodren)
  • Packaging100mg
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8475
  • Product descriptionMitotane(Lsodren)
  • Packaging10mM(in 1mL DMSO)
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8475
  • Product descriptionMitotane(Lsodren)
  • Packaging500mg
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134539
  • Product descriptionMitotane (Lysodren) >99%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134539
  • Product descriptionMitotane (Lysodren) >99%
  • Packaging250mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134539
  • Product descriptionMitotane (Lysodren) >99%
  • Packaging1g
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18651
  • Product descriptionMitotane ≥98%
  • Packaging100mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18651
  • Product descriptionMitotane ≥98%
  • Packaging250mg
  • Price$56
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-19139 Mitotan 99% 50g $325 2021-12-16 Buy
AK Scientific C599 1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane 250mg $49 2021-12-16 Buy
Ambeed A817688 1-Chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)benzene 99+% 1g $20 2021-12-16 Buy
Ambeed A817688 1-Chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)benzene 99+% 5g $64 2021-12-16 Buy
Ambeed A817688 1-Chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)benzene 99+% 25g $212 2021-12-16 Buy
American Custom Chemicals Corporation API0003407 MITOTANE 95.00% 1G $619.7 2021-12-16 Buy
American Custom Chemicals Corporation API0003407 MITOTANE 95.00% 2.5G $796.77 2021-12-16 Buy
American Custom Chemicals Corporation API0003407 MITOTANE 95.00% 5G $912.29 2021-12-16 Buy
ApexBio Technology A8475 Mitotane(Lsodren) 100mg $56 2021-12-16 Buy
ApexBio Technology A8475 Mitotane(Lsodren) 10mM(in 1mL DMSO) $80 2021-12-16 Buy
ApexBio Technology A8475 Mitotane(Lsodren) 500mg $112 2021-12-16 Buy
Biorbyt Ltd orb134539 Mitotane (Lysodren) >99% 100mg $510 2021-12-16 Buy
Biorbyt Ltd orb134539 Mitotane (Lysodren) >99% 250mg $765 2021-12-16 Buy
Biorbyt Ltd orb134539 Mitotane (Lysodren) >99% 1g $1504.5 2021-12-16 Buy
Cayman Chemical 18651 Mitotane ≥98% 100mg $32 2024-03-01 Buy
Cayman Chemical 18651 Mitotane ≥98% 250mg $56 2024-03-01 Buy

Properties

Melting point :77-78 °C(lit.)
Boiling point :405.59°C (rough estimate)
Density :1.3118 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO: soluble20mg/mL, clear
form :powder
color :white to beige
Water Solubility :<0.1 g/100 mL at 24 ºC
Merck :13,6237 / 13,6237
BRN :2056007
InChI :InChI=1S/C14H10Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8,13-14H
InChIKey :JWBOIMRXGHLCPP-UHFFFAOYSA-N
SMILES :C1(Cl)=CC=CC=C1C(C1=CC=C(Cl)C=C1)C(Cl)Cl
CAS DataBase Reference :53-19-0(CAS DataBase Reference)
NIST Chemistry Reference :Mitotane(53-19-0)
EPA Substance Registry System :

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Mitotane is an inhibitor of steroidogenesis that suppresses the growth of adrenocortical cells. It blocks the expression of several genes that encode proteins involved in steroidogenesis and disrupts mitochondrial respiratory chain activity in human adrenocortical cells. Mitotane has anti-neoplastic actions, alone or in combination with other compounds, and suppresses cortisol synthesis, although it also has significant toxicity in the gastrointestinal tract and nervous system. It is effective against adrenocortical carcinoma and Cushing’s Syndrome in clinical trials.

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