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ChemicalBook >> CAS DataBase List >> Mitoxantrone hydrochloride

Mitoxantrone hydrochloride

Mitoxantrone hydrochloride price.
  • $17 - $1900
  • Product name: Mitoxantrone hydrochloride
  • CAS: 70476-82-3
  • MF: C22H30Cl2N4O6
  • MW: 517.4028
  • EINECS:274-619-1
  • MDL Number:MFCD00242943
  • Synonyms:1,4-dihydroxy-5,8-bis(2-(2-hydroxyethylamino)ethylamino)anthracene-9,10-dione dihydrochloride;Mitoxantrone hydrochloride 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinone dihydrochloride;Mitoxantrone dihydrochloride, >=99%;MITOXANTRONE HYDROCHLORIDE;MITOXANTRONE HYDROCHLORIDE SALT;MITOXANTHRONE HCL;mitozantrone hydrochloride;DHAQ DIHYDROCHLORIDE
53 prices
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Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • Arctom
  • AstaTech
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
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  • m2305000
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  • 0.25G
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  • 1g
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  • 5G
  • 0.25/ G
  • 1/ G
  • 5/ G
  • ManufacturerAHH
  • Product numberAPI-1293
  • Product descriptionMitoxantrone hydrochloride 98%
  • Packaging1g
  • Price$610
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ98398
  • Product descriptionMitoxantrone Dihydrochloride
  • Packaging250mg
  • Price$158
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH492
  • Product descriptionMitoxantrone Dihydrochloride
  • Packaging500mg
  • Price$375
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ66341
  • Product descriptionMitoxantrone dihydrochloride
  • Packaging50mg
  • Price$152
  • Updated2023-06-20
  • Buy
  • ManufacturerAmbeed
  • Product numberA166750
  • Product description1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dionedihydrochloride 98+%
  • Packaging10mg
  • Price$17
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA166750
  • Product description1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dionedihydrochloride 98+%
  • Packaging50mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA166750
  • Product description1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dionedihydrochloride 98+%
  • Packaging100mg
  • Price$63
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA166750
  • Product description1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dionedihydrochloride 98+%
  • Packaging250mg
  • Price$92
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA166750
  • Product description1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dionedihydrochloride 98+%
  • Packaging1g
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0028666
  • Product descriptionMITOXANTRONE HYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$451.38
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60368
  • Product descriptionMitoxantrone2HCl ≥98%
  • Packaging20mg
  • Price$50
  • Updated2021-12-16
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  • ManufacturerAstaTech
  • Product number41800
  • Product descriptionMITOXANTRONE2HCL
  • Packaging0.25G
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerAstaTech
  • Product number41800
  • Product descriptionMITOXANTRONE2HCL 97%
  • Packaging0.25/ G
  • Price$158
  • Updated2021-12-16
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  • ManufacturerAstaTech
  • Product number41800
  • Product descriptionMITOXANTRONE2HCL
  • Packaging1G
  • Price$345
  • Updated2021-12-16
  • Buy
  • ManufacturerAstaTech
  • Product number41800
  • Product descriptionMITOXANTRONE2HCL 97%
  • Packaging1/ G
  • Price$395
  • Updated2021-12-16
  • Buy
  • ManufacturerAstaTech
  • Product number41800
  • Product descriptionMITOXANTRONE2HCL
  • Packaging5G
  • Price$1145
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1293 Mitoxantrone hydrochloride 98% 1g $610 2021-12-16 Buy
AK Scientific J98398 Mitoxantrone Dihydrochloride 250mg $158 2021-12-16 Buy
AK Scientific H492 Mitoxantrone Dihydrochloride 500mg $375 2021-12-16 Buy
Alfa Aesar J66341 Mitoxantrone dihydrochloride 50mg $152 2023-06-20 Buy
Ambeed A166750 1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dionedihydrochloride 98+% 10mg $17 2021-12-16 Buy
Ambeed A166750 1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dionedihydrochloride 98+% 50mg $35 2021-12-16 Buy
Ambeed A166750 1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dionedihydrochloride 98+% 100mg $63 2021-12-16 Buy
Ambeed A166750 1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dionedihydrochloride 98+% 250mg $92 2021-12-16 Buy
Ambeed A166750 1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dionedihydrochloride 98+% 1g $230 2021-12-16 Buy
American Custom Chemicals Corporation API0028666 MITOXANTRONE HYDROCHLORIDE 95.00% 5MG $451.38 2021-12-16 Buy
Arctom CFN60368 Mitoxantrone2HCl ≥98% 20mg $50 2021-12-16 Buy
AstaTech 41800 MITOXANTRONE2HCL 0.25G $99 2021-12-16 Buy
AstaTech 41800 MITOXANTRONE2HCL 97% 0.25/ G $158 2021-12-16 Buy
AstaTech 41800 MITOXANTRONE2HCL 1G $345 2021-12-16 Buy
AstaTech 41800 MITOXANTRONE2HCL 97% 1/ G $395 2021-12-16 Buy
AstaTech 41800 MITOXANTRONE2HCL 5G $1145 2021-12-16 Buy

Properties

Melting point :203-205 C
storage temp. :2-8°C
solubility :Sparingly soluble in water, slightly soluble in methanol, practically insoluble in acetone.
form :Solid
color :Dark Blue to Black
Water Solubility :Soluble to 5 mM in water and to 75 mM in DMSO
InChI :InChI=1S/C22H28N4O6.2ClH/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32;;/h1-4,23-30H,5-12H2;2*1H
InChIKey :ZAHQPTJLOCWVPG-UHFFFAOYSA-N
SMILES :C1(O)=C2C(C(=O)C3=C(C2=O)C(NCCNCCO)=CC=C3NCCNCCO)=C(O)C=C1.[H]Cl.[H]Cl
CAS DataBase Reference :70476-82-3(CAS DataBase Reference)
EPA Substance Registry System :Mitoxantrone hydrochloride (70476-82-3)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger GHS hazard pictograms
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Mitoxantrone is an anthraquinone that intercalates in DNA and inhibits topoisomerase II (IC50 = 5.3 μM), thus inhibiting cell proliferation. It also inhibits HIV-1 integrase (IC50 = 3.8 μM). Mitoxantrone is exported from cells in an ATP- and glutathione-dependent manner by multidrug resistance protein -1. This compound has found use in various forms of cancer and in multiple sclerosis.

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