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ChemicalBook >> CAS DataBase List >> α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile

α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile

α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile price.
  • $32 - $2839
  • Product name: α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile
  • CAS: 218136-59-5
  • MF: C27H29N5
  • MW: 423.55
  • EINECS:
  • MDL Number:MFCD11226148
  • Synonyms:SC 26196;α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile;alpha,alpha-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile;α,α-Diphenyl-4-[(3-pyridinylMethylene)aMino]-1-piperazine;2,2-diphenyl-5-{4-[(E)-(pyridin-3-ylMethylidene)aMino]piperazin-1-yl}pentanenitrile;PF-o6341724;(E)-2,2-diphenyl-5-(4-((pyridin-3-ylMethylene)aMino)piperazin-1-yl)pentanenitrile;2,2-diphenyl-5-(4-[[(1 E)-pyridin-3-yl-methylidene]amino]piperazin-1-yl)pentanenitrile
23 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 5MG
  • 10MG
  • 25mg
  • 50
  • 50mg
  • 100MG
  • 250mg
  • 1g
  • 1000mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010312
  • Product descriptionALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00%
  • Packaging100MG
  • Price$1686.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010312
  • Product descriptionALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00%
  • Packaging10MG
  • Price$716.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010312
  • Product descriptionALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00%
  • Packaging5MG
  • Price$242
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7608
  • Product descriptionSC26196
  • Packaging10mg
  • Price$202
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7608
  • Product descriptionSC26196
  • Packaging50mg
  • Price$852
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2112
  • Product descriptionSC26196-PF06341724 99%
  • Packaging25mg
  • Price$313.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180842
  • Product descriptionSC-26196 >98%
  • Packaging100mg
  • Price$838.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180842
  • Product descriptionSC-26196 >98%
  • Packaging250mg
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180842
  • Product descriptionSC-26196 >98%
  • Packaging1000mg
  • Price$2839
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10792
  • Product descriptionSC 26196 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10792
  • Product descriptionSC 26196 ≥98%
  • Packaging5mg
  • Price$122
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10792
  • Product descriptionSC 26196 ≥98%
  • Packaging10mg
  • Price$169
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10792
  • Product descriptionSC 26196 ≥98%
  • Packaging25mg
  • Price$381
  • Updated2024-03-01
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN26132
  • Product descriptionSC-26196
  • Packaging50mg
  • Price$656
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7029
  • Product descriptionSC-26196 >98%
  • Packaging1g
  • Price$1900
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7029
  • Product descriptionSC-26196 >98%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0010312 ALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00% 100MG $1686.3 2021-12-16 Buy
American Custom Chemicals Corporation API0010312 ALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00% 10MG $716.1 2021-12-16 Buy
American Custom Chemicals Corporation API0010312 ALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00% 5MG $242 2021-12-16 Buy
ApexBio Technology B7608 SC26196 10mg $202 2021-12-16 Buy
ApexBio Technology B7608 SC26196 50mg $852 2021-12-16 Buy
Axon Medchem Axon2112 SC26196-PF06341724 99% 25mg $313.5 2021-12-16 Buy
Biorbyt Ltd orb180842 SC-26196 >98% 100mg $838.1 2021-12-16 Buy
Biorbyt Ltd orb180842 SC-26196 >98% 250mg $1504.5 2021-12-16 Buy
Biorbyt Ltd orb180842 SC-26196 >98% 1000mg $2839 2021-12-16 Buy
Cayman Chemical 10792 SC 26196 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 10792 SC 26196 ≥98% 5mg $122 2024-03-01 Buy
Cayman Chemical 10792 SC 26196 ≥98% 10mg $169 2024-03-01 Buy
Cayman Chemical 10792 SC 26196 ≥98% 25mg $381 2024-03-01 Buy
CSNpharm CSN26132 SC-26196 50mg $656 2021-12-16 Buy
DC Chemicals DC7029 SC-26196 >98% 1g $1900 2021-12-16 Buy
DC Chemicals DC7029 SC-26196 >98% 100mg $550 2021-12-16 Buy

Properties

storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
form :powder
color :white to tan

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SC 26196 is an inhibitor of Δ6 desaturase (IC50 = 0.2 μM in a rat liver microsomal assay) that completely blocks the conversion of linoleic acid to arachidonic acid (AA). It is selective for Δ6 desaturase, as IC50 values for Δ5 and Δ9 desaturases exceed 200 μM and it has no effect on the conversion of dihomo-γ-linolenic acid to AA. SC 26196 is orally active in vivo, decreasing edema in the carrageenan paw edema model in mice. It also blocks aging-related increases in AA in myocardial cardiolipin in mice, attenuating contractile dysfunction without impacting mitochondrial oxidative stress.

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